1. Academic Validation
  2. Polyhydroxylated steroidal glycosides from Paris polyphylla

Polyhydroxylated steroidal glycosides from Paris polyphylla

  • J Nat Prod. 2012 Jun 22;75(6):1201-5. doi: 10.1021/np300045g.
Li-Ping Kang 1 Yi-Xun Liu Tolga Eichhorn Else Dapat He-shui Yu Yang Zhao Cheng-Qi Xiong Chao Liu Thomas Efferth Bai-Ping Ma
Affiliations

Affiliation

  • 1 Beijing Institute of Radiation Medicine, Beijing 100850, People's Republic of China.
Abstract

Three new steroidal saponins, parisyunnanosides G-I (1-3), one new C(21) steroidal glycoside, parisyunnanoside J (4), and three known compounds, padelaoside B (5), pinnatasterone (6), and 20-hydroxyecdyson (7), were isolated from the rhizomes of Paris polyphylla Smith var. yunnanensis. Compounds 1 and 3 have unique trisdesmoside structures that include a C-21 β-d-galactopyranose moiety. All compounds were evaluated for their cytotoxicity against human CCRF leukemia cells.

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