2. Academic Validation
  3. Antibacterial compounds from Zanthoxylum rhetsa

Antibacterial compounds from Zanthoxylum rhetsa

  • Arch Pharm Res. 2012 Jul;35(7):1139-42. doi: 10.1007/s12272-012-0703-9.
Cholpisut Tantapakul 1,  Wong Phakhodee,  Thunwadee Ritthiwigrom,  Kulsiri Yossathera,  Suwanna Deachathai,  Surat Laphookhieo
Affiliations

Affiliation

  • 1 Natural Products Research Laboratory, School of Science, Mae Fah Luang University, Tasud, Muang, Chiang Rai 57100, Thailand.
PMID: 22864735 DOI: 10.1007/s12272-012-0703-9
Abstract

A new amide, zanthorhetsamide (1), along with nine known compounds (2-10) was isolated from the roots and stem barks of Zanthoxylum rhetsa. The structure was characterized by spectroscopic methods. In addition, the Antibacterial activity of the isolates was evaluated. Dihydrochelerythrine (4) exhibited strong activity against methicillin-resistant Staphylococcus aureus SK1 and moderate activity against Escherichia coli TISTR 780 with MIC values of 8 and 16 μg/mL, respectively.

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