1. Academic Validation
  2. A new sesquiterpene from Kalimeris integrifolia

A new sesquiterpene from Kalimeris integrifolia

  • Nat Prod Res. 2018 May;32(9):1004-1009. doi: 10.1080/14786419.2017.1375917.
Guo-Kai Wang 1 2 Zheng Wang 1 Yang Yu 1 Nan Zhang 1 Zhong-Yu Zhou 3 Gang Wang 1 2 Jin-Song Liu 1 2
Affiliations

Affiliations

  • 1 a Anhui Key Laboratory of Modern Chinese Materia Medica, School of Pharmacy , Anhui University of Chinese Medicine , Hefei , China.
  • 2 b Synergetic Innovation Center of Anhui Authentic Chinese Medicine Quality Improvement , Hefei , P.R. China.
  • 3 c Guang dong Provincial Key Laboratory of Applied Botany, South China Botanical Garden , Chinese Academy of Sciences , Guangzhou , China.
Abstract

A new sesquiterpene kalinturoside A (1), and 17 known compounds friedelan-3-ol (2), 24-ethyl-5a-cholesta-7, 22(E)-dien-3-one (3), friedelin (4), syringaresinol (5), α-spinasterol (6), ciwujiatone (7), syringic acid (8), scopoletin (9), apocynin (10), 1-(3-hydroxy-4, 5-dimethoxyphenyl)ethan-1-one (11), apigenin (12), 5-hydroxymethylfurfural (13), stigmasterol-3-O-β-d-glucopy-ranoside (14), bidenoside C (15), citrusin (16), irioresinol A (17) and syringaresinol-4-O-β-d-glucopyranoside (18) were isolated from the herbs of Kalimeris integrifolia. The structures of these compounds were elucidated using spectroscopic techniques such as NMR and MS. All of the compounds were isolated from this genus for the first time.

Keywords

Kalimeris integrifolia; cytotoxic activity; kalinturoside A; sesquiterpene.

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