1. Academic Validation
  2. Essential Oils and Supercritical CO2 Extracts of Arctic Angelica ( Angelica archangelica L.), Marsh Labrador Tea ( Rhododendron tomentosum) and Common Tansy ( Tanacetum vulgare)-Chemical Compositions and Antimicrobial Activities

Essential Oils and Supercritical CO2 Extracts of Arctic Angelica ( Angelica archangelica L.), Marsh Labrador Tea ( Rhododendron tomentosum) and Common Tansy ( Tanacetum vulgare)-Chemical Compositions and Antimicrobial Activities

  • Molecules. 2021 Nov 25;26(23):7121. doi: 10.3390/molecules26237121.
Risto I Korpinen 1 2 Anna-Liisa Välimaa 3 Jaana Liimatainen 1 Susan Kunnas 4
Affiliations

Affiliations

  • 1 Production Systems, Natural Resources Institute Finland, Tietotie 2, 02150 Espoo, Finland.
  • 2 Separation Science, LUT School of Engineering Science, LUT University, Yliopistonkatu 34, 53850 Lappeenranta, Finland.
  • 3 Production Systems, Natural Resources Institute Finland, Paavo Havaksentie 3, 90570 Oulu, Finland.
  • 4 Production Systems, Natural Resources Institute Finland, Ounasjoentie 6, 96200 Rovaniemi, Finland.
Abstract

Traditionally, arctic Finnish Angelica (Angelica archangelica L.), marsh Labrador tea (Rhododendron tomentosum, syn. Ledum palustre) and common tansy (Tanacetum vulgare) have been used as medicinal herbs in folklore medicine. However, these underutilised Plants are a source of, e.g., oil-based compounds, which could benefit many modern applications implemented by the green chemistry extraction methods, as well. We extracted Angelica, marsh Labrador tea and common tansy by non-toxic and recyclable extraction methods, i.e., hydrodistillation and supercritical carbon dioxide (scCO2) extraction; characterised the essential oils (EOs) and scCO2 extracts by combination of gas chromatography and mass spectrometry (GC-MS), and in addition, analysed the antimicrobial properties. As expected for Angelica root and common tansy inflorescence, the scCO2 extraction method produced less amount of volatile compounds compared to hydrodistillation. On the other hand, more Coumarins, alkanes, fatty alcohols and fatty acids were obtained. Additionally, sesquiterpenoids palustrol and ledol were predominant compounds in both marsh Labrador tea EO and scCO2 extract. According to our results, however, all the EOs and scCO2 extracts showed broad spectrum of antimicrobial activities against the selected microbes, but the effects were extract-specific. The strongest and broadest antimicrobial activities were performed by marsh Labrador tea scCO2 extract, which showed extremely strong effect on Staphylococcusaureus subsp. aureus and strong effect on Candida albicans.

Keywords

Angelica; GC-MS chromatography; antimicrobial activity; common tansy; essential oils; marsh Labrador tea; plant extracts; steam distillation; supercritical carbon dioxide extraction.

Figures
Products
  • Cat. No.
    Product Name
    Description
    Target
    Research Area
  • HY-122375
    Sesquiterpenoid