2. Others Apoptosis
  3. Fluorescent Dye Ferroptosis
  4. Mito-Rh-S

Mito-Rh-S is a ratiometric near-infrared (NIR) fluorescent probe that detects the fluctuation of mitochondrial HClO levels during ferroptosis in hepatocellular carcinoma (HCC).

For research use only. We do not sell to patients.

Mito-Rh-S Chemical Structure

Mito-Rh-S Chemical Structure

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Mito-Rh-S Related Antibodies

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Description

Mito-Rh-S is a ratiometric near-infrared (NIR) fluorescent probe that detects the fluctuation of mitochondrial HClO levels during ferroptosis in hepatocellular carcinoma (HCC)[1].

In Vitro

Mito-Rh-S has an ultrafast response rate (2s) and large emission shift (115 nm). Mito-Rh-S has a high signal-to-noise ratio[1].
The cell experiments of Mito-Rh-S demonstrated that Fe2+- and Erastin-induced ferroptosis in HepG2 cells resulted in elevated levels of mitochondrial HClO[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Mito-Rh-S Related Antibodies
Molecular Weight

695.27

Formula

C40H39ClN2O5S
Unlabeled Cas

SMILES

CCN1C(C=CC=C2)=C2SC(C=C3/C=C4C5=[O+]C6=CC(N(CC)CC)=CC=C6C(C7=C(C(O)=O)C=CC=C7)=C5CCC/4)=C1C=C3OC.Cl[O-]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Mito-Rh-S Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Mito-Rh-SFluorescent DyeFerroptosisHClO fluorescent probenear-infraredhepatocellular carcinomaInhibitorinhibitorinhibit

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HY-D2312
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