2. Immunology/Inflammation
  3. MyD88
  4. MyD88-IN-1

MyD88-IN-1 is a potent MyD88 inhibitor. MyD88-IN-1 inhibits the interaction of TLR4 and MyD88 and suppressed the NF-κB pathway. MyD88-IN-1 can be used in research of cancer and inflammatory.

For research use only. We do not sell to patients.

MyD88-IN-1 Chemical Structure

MyD88-IN-1 Chemical Structure

CAS No. : 2911609-80-6

Size Price Stock Quantity
Solid + Solvent
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 267 In-stock
Solution
10 mM * 1 mL in DMSO USD 267 In-stock
Solid
1 mg USD 60 In-stock
5 mg USD 230 In-stock
10 mg USD 390 In-stock
50 mg USD 590 In-stock
100 mg USD 840 In-stock
200 mg   Get quote  
500 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

MyD88-IN-1 Related Antibodies

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Description

MyD88-IN-1 is a potent MyD88 inhibitor. MyD88-IN-1 inhibits the interaction of TLR4 and MyD88 and suppressed the NF-κB pathway. MyD88-IN-1 can be used in research of cancer and inflammatory[1].

Molecular Weight

528.54

Formula

C23H24N6O7S
CAS No.
Appearance

Solid

Color

Yellow to orange

SMILES

O=[N+](C1=CC=CC(CN2CCN(CC2)C3=CC=C(S(=O)(NC4=CN=C(C=C4)OC)=O)C=C3[N+]([O-])=O)=C1)[O-]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (189.20 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8920 mL 9.4600 mL 18.9200 mL
5 mM 0.3784 mL 1.8920 mL 3.7840 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

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Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.95%

COA (247 KB) HNMR (280 KB) LCMS (93 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.8920 mL 9.4600 mL 18.9200 mL 47.3001 mL
5 mM 0.3784 mL 1.8920 mL 3.7840 mL 9.4600 mL
10 mM 0.1892 mL 0.9460 mL 1.8920 mL 4.7300 mL
15 mM 0.1261 mL 0.6307 mL 1.2613 mL 3.1533 mL
20 mM 0.0946 mL 0.4730 mL 0.9460 mL 2.3650 mL
25 mM 0.0757 mL 0.3784 mL 0.7568 mL 1.8920 mL
30 mM 0.0631 mL 0.3153 mL 0.6307 mL 1.5767 mL
40 mM 0.0473 mL 0.2365 mL 0.4730 mL 1.1825 mL
50 mM 0.0378 mL 0.1892 mL 0.3784 mL 0.9460 mL
60 mM 0.0315 mL 0.1577 mL 0.3153 mL 0.7883 mL
80 mM 0.0237 mL 0.1183 mL 0.2365 mL 0.5913 mL
100 mM 0.0189 mL 0.0946 mL 0.1892 mL 0.4730 mL
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MyD88-IN-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MyD88-IN-12911609-80-6MyD88Inhibitorinhibitorinhibit

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