2. Cell Cycle/DNA Damage
  3. Nucleoside Antimetabolite/Analog DNA/RNA Synthesis
  4. N1-Methylpseudouridine-5′-triphosphate trisodium

N1-Methylpseudouridine-5′-triphosphate trisodium  (Synonyms: 1-Methylpseudouridine-5′-triphosphate trisodium)

Cat. No.: HY-112582C Purity: ≥99.0%
COA Handling Instructions

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N1-Methylpseudouridine-5′-triphosphate (1-Methylpseudouridine-5′-triphosphate) trisodium is a nucleobase-modified nucleotide, used for synthesizing mRNA with reduced immunogenicity and improved stability.

For research use only. We do not sell to patients.

N1-Methylpseudouridine-5′-triphosphate trisodium Chemical Structure

N1-Methylpseudouridine-5′-triphosphate trisodium Chemical Structure

Size Price Stock Quantity
Solvent
5641 μg (100 mM*100 μL in water) USD 150 In-stock
Solvent
11282 μg (100 mM*200 μL in water) USD 240 In-stock
Solvent
28205 μg (100 mM*500 μL in water) USD 470 In-stock
Solvent
56411 μg (100 mM*1 mL in water) USD 750 In-stock
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Based on 1 publication(s) in Google Scholar

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N1-Methylpseudouridine-5′-triphosphate trisodium Related Antibodies

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Description

N1-Methylpseudouridine-5′-triphosphate (1-Methylpseudouridine-5′-triphosphate) trisodium is a nucleobase-modified nucleotide, used for synthesizing mRNA with reduced immunogenicity and improved stability[1].

Molecular Weight

564.11

Formula

C10H14N2Na3O15P3
Appearance

Liquid

Color

Colorless to light yellow

SMILES

O[C@H]1[C@@H](O)[C@H](C(C(N2)=O)=CN(C)C2=O)O[C@@H]1COP(OP(OP(O)(O[Na])=O)(O[Na])=O)(O[Na])=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Solution, -20°C, 2 years
Solvent & Solubility
In Vitro: 

H2O : 10 mg/mL (17.73 mM; Need ultrasonic)

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥99.0%

COA (255 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.7727 mL 8.8635 mL 17.7270 mL 44.3176 mL
5 mM 0.3545 mL 1.7727 mL 3.5454 mL 8.8635 mL
10 mM 0.1773 mL 0.8864 mL 1.7727 mL 4.4318 mL
15 mM 0.1182 mL 0.5909 mL 1.1818 mL 2.9545 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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N1-Methylpseudouridine-5′-triphosphate trisodium Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

N1-Methylpseudouridine-5′-triphosphate trisodium1-Methylpseudouridine-5′-triphosphate trisodiumNucleoside Antimetabolite/AnalogDNA/RNA Synthesisnucleobase-modified nucleotidemRNAInhibitorinhibitorinhibit

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