O-Benzylhydroxylamine hydrochloride

Cat. No.: HY-41915 Purity: ≥97.0%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

O-Benzylhydroxylamine hydrochloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

For research use only. We do not sell to patients.

O-Benzylhydroxylamine hydrochloride Chemical Structure

CAS No. : 2687-43-6

Size	Price	Stock	Quantity
100 g	USD 30	In-stock	Estimated Time of Arrival: December 31
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Description

O-Benzylhydroxylamine hydrochloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

In Vitro

O-Benzylhydroxylamine is a building block. It has been used in the synthesis of β-lactam inhibitor precursors and fluoroquinolone derivatives with antibiotic activity.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

159.61

Formula

C₇H₁₀ClNO

CAS No.

2687-43-6

Appearance

Solid

Color

White to off-white

SMILES

NOCC1=CC=CC=C1.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (626.53 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	6.2653 mL	31.3264 mL	62.6527 mL
5 mM	1.2531 mL	6.2653 mL	12.5305 mL
10 mM	0.6265 mL	3.1326 mL	6.2653 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 90% Corn Oil
Solubility: ≥ 2.5 mg/mL (15.66 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

DMSO +

Tween-80 +

Saline

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.

The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Calculation results:

Working solution concentration: mg/mL

Method for preparing stock solution: mg drug dissolved in μL DMSO (Stock solution concentration: mg/mL).

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).

Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.

If the continuous dosing period exceeds half a month, please choose this protocol carefully.

Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.

Purity & Documentation

Purity: 97.64%

Select Batch:

Data Sheet (243 KB) SDS (0 KB)

COA (247 KB) HNMR (116 KB) RP-HPLC (188 KB) LCMS (236 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	6.2653 mL	31.3264 mL	62.6527 mL	156.6318 mL
	5 mM	1.2531 mL	6.2653 mL	12.5305 mL	31.3264 mL
	10 mM	0.6265 mL	3.1326 mL	6.2653 mL	15.6632 mL
	15 mM	0.4177 mL	2.0884 mL	4.1768 mL	10.4421 mL
	20 mM	0.3133 mL	1.5663 mL	3.1326 mL	7.8316 mL
	25 mM	0.2506 mL	1.2531 mL	2.5061 mL	6.2653 mL
	30 mM	0.2088 mL	1.0442 mL	2.0884 mL	5.2211 mL
	40 mM	0.1566 mL	0.7832 mL	1.5663 mL	3.9158 mL
	50 mM	0.1253 mL	0.6265 mL	1.2531 mL	3.1326 mL
	60 mM	0.1044 mL	0.5221 mL	1.0442 mL	2.6105 mL
	80 mM	0.0783 mL	0.3916 mL	0.7832 mL	1.9579 mL
	100 mM	0.0627 mL	0.3133 mL	0.6265 mL	1.5663 mL

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

O-Benzylhydroxylamine2687-43-6Inhibitorinhibitorinhibit

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O-Benzylhydroxylamine hydrochloride