2. Metabolic Enzyme/Protease
  3. Carbonic Anhydrase Drug Metabolite
  4. O-Desmethyl Brinzolamide hydrochloride

O-Desmethyl Brinzolamide hydrochloride (compound 6a), an active metabolite of Brinzolamide, is a carbonic anhydrase (CA) inhibitor with a Kd of 0.136 nM for CA II and an IC50 of 165 nM for CA IV.

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O-Desmethyl Brinzolamide hydrochloride Chemical Structure

O-Desmethyl Brinzolamide hydrochloride Chemical Structure

CAS No. : 2967475-56-3

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O-Desmethyl Brinzolamide hydrochloride Related Antibodies

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Description

O-Desmethyl Brinzolamide hydrochloride (compound 6a), an active metabolite of Brinzolamide, is a carbonic anhydrase (CA) inhibitor with a Kd of 0.136 nM for CA II and an IC50 of 165 nM for CA IV[1].

Molecular Weight

405.94

Formula

C11H20ClN3O5S3
CAS No.
SMILES

CCN[C@H]1CN(CCCO)S(=O)(C2=C1C=C(S(=O)(N)=O)S2)=O.[H]Cl
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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O-Desmethyl Brinzolamide hydrochloride Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

O-Desmethyl Brinzolamide2967475-56-3 Carbonic AnhydraseDrug MetaboliteCarbonate dehydrataseBrinzolamideactive metaboliteCA IICA IVInhibitorinhibitorinhibit

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