2. Immunology/Inflammation
  3. CD20
  4. Ocrelizumab

Ocrelizumab  (Synonyms: Ocrevus)

Cat. No.: HY-P9960 Purity: 95.00%
COA

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Ocrelizumab is an anti-CD20 antibody that depletes circulating immature and mature B cells but spares CD20-negative plasma cells. The effector mechanisms of Ocrelizumab are complement-dependent cytotoxicity and antibody-dependent cellular cytotoxicity. Ocrelizumab is the first monoclonal antibody for secondary primary progressive multiple sclerosis (PPMS).

For research use only. We do not sell to patients.

Ocrelizumab Chemical Structure

Ocrelizumab Chemical Structure

CAS No. : 637334-45-3

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5 mg USD 780 In-stock
10 mg USD 1250 In-stock
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Based on 1 publication(s) in Google Scholar

Ocrelizumab Related Antibodies

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Description

Ocrelizumab is an anti-CD20 antibody that depletes circulating immature and mature B cells but spares CD20-negative plasma cells. The effector mechanisms of Ocrelizumab are complement-dependent cytotoxicity and antibody-dependent cellular cytotoxicity. Ocrelizumab is the first monoclonal antibody for secondary primary progressive multiple sclerosis (PPMS)[1].

Clinical Trial
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Ocrelizumab]
Shipping

Shipping with dry ice.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation

Purity: 95.00%

COA (231 KB)

Handling Instructions (2659 KB)
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Ocrelizumab Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ocrelizumab637334-45-3OcrevusCD20antidodyPPMSInhibitorinhibitorinhibit

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