2. Antibody-drug Conjugate/ADC Related Cell Cycle/DNA Damage
  3. Drug-Linker Conjugates for ADC Topoisomerase
  4. P5(PEG24)-VC-PAB-exatecan

P5(PEG24)-VC-PAB-exatecan is a camptothecin-based linker-payload platform based on the highly potent camptothecin derivative exatecan. P5(PEG24)-VC-PAB-exatecan has linker-payload structures. P5(PEG24)-VC-PAB-exatecan can be used for the research of tumor.

For research use only. We do not sell to patients.

P5(PEG24)-VC-PAB-exatecan Chemical Structure

P5(PEG24)-VC-PAB-exatecan Chemical Structure

CAS No. : 2928571-43-9

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Based on 1 publication(s) in Google Scholar

P5(PEG24)-VC-PAB-exatecan Related Antibodies

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Description

P5(PEG24)-VC-PAB-exatecan is a camptothecin-based linker-payload platform based on the highly potent camptothecin derivative exatecan. P5(PEG24)-VC-PAB-exatecan has linker-payload structures. P5(PEG24)-VC-PAB-exatecan can be used for the research of tumor[1].

IC50 & Target

Camptothecins

 

Molecular Weight

2105.31

Formula

C100H151FN9O36P
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=P(C#C)(NC1=CC=C(C=C1)C(N[C@@H](C(C)C)C(N[C@H](C(NC2=CC=C(C=C2)COC(N[C@H]3CCC4=C5C(N=C6C7=CC8=C(C(N7CC6=C53)=O)COC([C@@]8(CC)O)=O)=CC(F)=C4C)=O)=O)CCCNC(N)=O)=O)=O)OCCOCCO.[23]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Purity & Documentation
References
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P5(PEG24)-VC-PAB-exatecan Related Classifications

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

P5(PEG24)-VC-PAB-exatecan2928571-43-9Drug-Linker Conjugates for ADCTopoisomerasecamptothecin-basedlinker-payload platformtumorInhibitorinhibitorinhibit

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