2. Epigenetics Metabolic Enzyme/Protease
  3. Epigenetic Reader Domain PGC-1α
  4. Phoenixin-20

Phoenixin-20  (Synonyms: PNX-20)

Cat. No.: HY-P5763 Purity: 99.68%
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Phoenixin-20 (PNX-20) is a bioactive peptide with hormone-like actions in vertebrates, and can stimulates hypothalamo-pituitary-gonadal hormones and regulate reproductive processes in mammals. Phoenixin-20 promotes neuronal mitochondrial biogenesis via CREB-PGC-1α pathway. Phoenixin-20 has anxiolytic effect.

For research use only. We do not sell to patients.

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Phoenixin-20 Chemical Structure

Phoenixin-20 Chemical Structure

CAS No. : 1415039-77-8

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5 mg USD 300 In-stock
10 mg USD 450 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Phoenixin-20 (PNX-20) is a bioactive peptide with hormone-like actions in vertebrates, and can stimulates hypothalamo-pituitary-gonadal hormones and regulate reproductive processes in mammals. Phoenixin-20 promotes neuronal mitochondrial biogenesis via CREB-PGC-1α pathway. Phoenixin-20 has anxiolytic effect[1][2][3].

Molecular Weight

2181.45

Formula

C101H153N25O29
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Ala-Gly-Ile-Val-Gln-Glu-Asp-Val-Gln-Pro-Pro-Gly-Leu-Lys-Val-Trp-Ser-Asp-Pro-Phe-NH2
Sequence Shortening

AGIVQEDVQPPGLKVWSDPF-NH2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture and light

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (22.92 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.4584 mL 2.2921 mL 4.5841 mL
5 mM 0.0917 mL 0.4584 mL 0.9168 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.4584 mL 2.2921 mL 4.5841 mL 11.4603 mL
5 mM 0.0917 mL 0.4584 mL 0.9168 mL 2.2921 mL
10 mM 0.0458 mL 0.2292 mL 0.4584 mL 1.1460 mL
15 mM 0.0306 mL 0.1528 mL 0.3056 mL 0.7640 mL
20 mM 0.0229 mL 0.1146 mL 0.2292 mL 0.5730 mL
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Phoenixin-20 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Phoenixin-201415039-77-8PNX-20Phoenixin20Phoenixin 20PNX20PNX 20Epigenetic Reader DomainPGC-1αPPARγ coactivator-1αNeurodegenerative disordersmitochondrial biogenesisNeuronal cellsInhibitorinhibitorinhibit

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