The choice of delivery method is crucial in drug research and treatment. Different administration routes include oral administration, intravenous injection, subcutaneous injection, transdermal absorption, respiratory tract administration, etc. Oral administration is a common and convenient route and is suitable for oral preparations. Intravenous injection allows the drug to quickly reach the systemic circulation and is suitable for emergency situations. Subcutaneous injection is suitable for slow-release formulations. Transdermal absorption is suitable for local treatment, and respiratory administration can directly affect the respiratory system. The choice of administration method needs to consider the properties of the drug, therapeutic goals, pharmacodynamics and patient acceptance to improve the therapeutic effect.