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  5. CD81 Protein, Cynomolgus/Rhesus Macaque (HEK293, His)

CD81 Protein, Cynomolgus/Rhesus Macaque (HEK293, His)

Cat. No.: HY-P76244
Handling Instructions

The CD81 protein is a member of the growth hormone/prolactin family and regulates a variety of physiological processes. Prolactin is mainly associated with mammary gland development and lactation, has pleiotropic effects, and affects immune responses, metabolism, and behavior. CD81 Protein, Cynomolgus/Rhesus Macaque (HEK293, His) is the recombinant Rhesus Macaque-derived CD81 protein, expressed by HEK293 , with N-His labeled tag. The total length of CD81 Protein, Cynomolgus/Rhesus Macaque (HEK293, His) is 86 a.a., with molecular weight of ~10 KDa.

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Description

The CD81 protein is a member of the growth hormone/prolactin family and regulates a variety of physiological processes. Prolactin is mainly associated with mammary gland development and lactation, has pleiotropic effects, and affects immune responses, metabolism, and behavior. CD81 Protein, Cynomolgus/Rhesus Macaque (HEK293, His) is the recombinant Rhesus Macaque-derived CD81 protein, expressed by HEK293 , with N-His labeled tag. The total length of CD81 Protein, Cynomolgus/Rhesus Macaque (HEK293, His) is 86 a.a., with molecular weight of ~10 KDa.

Background

Prolactin is a member of the somatotropin/prolactin family, playing a crucial role in regulating various physiological processes. As a hormone, prolactin is primarily associated with the modulation of mammary gland development and lactation in mammals. Beyond its reproductive functions, prolactin also exhibits pleiotropic effects, influencing immune responses, metabolism, and behavior. The somatotropin/prolactin family encompasses proteins that share structural and functional similarities, reflecting their evolutionary relationship and involvement in diverse biological pathways. Prolactin's versatility highlights its significance in orchestrating a range of physiological functions, making it a key player in maintaining homeostasis in different tissues and systems.

Species

Rhesus Macaque/Cynomolgus

Source

HEK293

Tag

N-6*His

Accession

A0A2K5UDJ9 (K116-K201)

Gene ID

102139656  [NCBI]

Molecular Construction
N-term
His
CD81 (K116-K201)
Accession # A0A2K5UDJ9
C-term
Synonyms
CD81 antigen; CD81; CVID6; TAPA-1; TSPAN28
AA Sequence

KDQIAKDVKQFYDQALQQAVVDDDANNAKAVVKTFHETLDCCGSSTLAALTTSVLKNNLCPSGSNIISNLLKKDCHQKIDELFSGK

Molecular Weight

Approximately 10 kDa.

Purity

Greater than 95% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

CD81 Protein, Cynomolgus/Rhesus Macaque (HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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CD81 Protein, Cynomolgus/Rhesus Macaque (HEK293, His)
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HY-P76244
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