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  2. CD Antigens
  3. Dendritic Cell CD Proteins
  4. DEC-205/CD205
  5. DEC-205/CD205 Protein, Cynomolgus (HEK293, His)

DEC-205/CD205 Protein, Cynomolgus (HEK293, His)

Cat. No.: HY-P701022
Handling Instructions

DEC-205/CD205 Protein, an endocytic receptor, transports captured antigens to a specialized processing compartment, placing it at the forefront of antigen presentation. This role is crucial for immune surveillance and initiating immune responses. DEC-205/CD205's involvement also downregulates B-lymphocyte proliferation, showcasing its regulatory impact on immune cell dynamics and responses. DEC-205/CD205 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived DEC-205/CD205 protein, expressed by HEK293 , with C-His labeled tag. The total length of DEC-205/CD205 Protein, Cynomolgus (HEK293, His) is 1639 a.a., with molecular weight of 230-245 kDa.

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Description

DEC-205/CD205 Protein, an endocytic receptor, transports captured antigens to a specialized processing compartment, placing it at the forefront of antigen presentation. This role is crucial for immune surveillance and initiating immune responses. DEC-205/CD205's involvement also downregulates B-lymphocyte proliferation, showcasing its regulatory impact on immune cell dynamics and responses. DEC-205/CD205 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived DEC-205/CD205 protein, expressed by HEK293 , with C-His labeled tag. The total length of DEC-205/CD205 Protein, Cynomolgus (HEK293, His) is 1639 a.a., with molecular weight of 230-245 kDa.

Background

DEC-205/CD205 protein serves as an endocytic receptor, facilitating the transportation of captured antigens from the extracellular space to a specialized antigen-processing compartment. This function positions DEC-205/CD205 at the forefront of antigen presentation, playing a crucial role in immune surveillance and the initiation of immune responses. Moreover, its involvement leads to the downregulation of B-lymphocyte proliferation, highlighting its regulatory impact on immune cell dynamics and responses.

Species

Cynomolgus

Source

HEK293

Tag

C-His

Accession

XP_005573337.2 (S28-D1666)

Gene ID

102120600  [NCBI]

Molecular Construction
N-term
CD205 (S28-D1666)
Accession # XP_005573337.2
His
C-term
Synonyms
Ly-75; DEC-205; CD205; CLEC13B; GP200-MR6; LY75
Molecular Weight

230-245 kDa

Purity

Greater than 95% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

DEC-205/CD205 Protein, Cynomolgus (HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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DEC-205/CD205 Protein, Cynomolgus (HEK293, His)
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HY-P701022
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