LDCC Protein, E.coli (His)

LDCC protein is also called lysine decarboxylase. As an enzyme that can catalyze the decarboxylation of lysine, it plays a key role in the utilization of lysine. This enzymatic activity enables LDCC to remove carboxyl groups from lysine, thereby generating cadaverine, a biogenic amine. LDCC Protein, E.coli (His) is the recombinant E. coli-derived LDCC protein, expressed by E. coli , with C-6*His labeled tag. The total length of LDCC Protein, E.coli (His) is 713 a.a., with molecular weight of 85 kDa.

LDCC protein, also known as lysine decarboxylase, plays a critical role in the utilization of lysine by acting as an enzyme capable of catalyzing the decarboxylation of lysine. This enzymatic activity allows LDCC to remove a carboxyl group from lysine, consequently generating cadaverine, a biogenic amine. Cadaverine is involved in various biological processes and has been implicated in the modulation of cell growth, differentiation, and immune responses. LDCC's function as a lysine decarboxylase is crucial for the efficient utilization of lysine in cellular metabolism, and further research is needed to fully understand its regulatory mechanisms and potential applications in various biological contexts.

1.The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.
2.Measured by its binding ability in a functional ELISA. Immobilized ldcC at 2 μg/mL can bind human ycbX, the EC₅₀ of human ycbX protein is ≤90 μg/mL.

E.coli

E. coli

C-6*His

P52095 (M1-G713)

66671526  [NCBI]

MNIIAIMGPHGVFYKDEPIKELESALVAQGFQIIWPQNSVDLLKFIEHNPRICGVIFDWDEYSLDLCSDINQLNEYLPLYAFINTHSTMDVSVQDMRMALWFFEYALGQAEDIAIRMRQYTDEYLDNITPPFTKALFTYVKERKYTFCTPGHMGGTAYQKSPVGCLFYDFFGGNTLKADVSISVTELGSLLDHTGPHLEAEEYIARTFGAEQSYIVTNGTSTSNKIVGMYAAPSGSTLLIDRNCHKSLAHLLMMNDVVPVWLKPTRNALGILGGIPRREFTRDSIEEKVAATTQAQWPVHAVITNSTYDGLLYNTDWIKQTLDVPSIHFDSAWVPYTHFHPIYQGKSGMSGERVAGKVIFETQSTHKMLAALSQASLIHIKGEYDEEAFNEAFMMHTTTSPSYPIVASVETAAAMLRGNPGKRLINRSVERALHFRKEVQRLREESDGWFFDIWQPPQVDEAECWPVAPGEQWHGFNDADADHMFLDPVKVTILTPGMDEQGNMSEEGIPAALVAKFLDERGIVVEKTGPYNLLFLFSIGIDKTKAMGLLRGLTEFKRSYDLNLRIKNMLPDLYAEDPDFYRNMRIQDLAQGIHKLIRKHDLPGLMLRAFDTLPEMIMTPHQAWQRQIKGEVETIALEQLVGRVSANMILPYPPGVPLLMPGEMLTKESRTVLDFLLMLCSVGQHYPGFETDIHGAKQDEDGVYRVRVLKMAG

85 kDa

Greater than 90% as determined by reducing SDS-PAGE.

Lyophilized powder

Lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.