NKp46/NCR1 Protein, Rat (HEK293, Fc)

The NKp46/NCR1 protein is a key cytotoxic activating receptor that increases the efficiency of activated natural killer (NK) cells, particularly in targeting tumor cell lysis. Through interactions with CD3Z and FCER1G, NKp46/NCR1 orchestrates important connections that enhance the ability of NK cells to destroy tumor cells. NKp46/NCR1 Protein, Rat (HEK293, Fc) is the recombinant rat-derived NKp46/NCR1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of NKp46/NCR1 Protein, Rat (HEK293, Fc) is 239 a.a., with molecular weight of ~65 & 36 KDa, respectively.

As a cytotoxicity-activating receptor, NKp46/NCR1 stands at the forefront of natural killer (NK) cell functionality, potentially bolstering the efficacy of activated NK cells in the targeted lysis of tumor cells. This receptor, instrumental in mediating the cytotoxicity response, engages with CD3Z and FCER1G, thereby orchestrating essential interactions that enhance the NK cell's capacity for tumor cell destruction. The intricate interplay between NKp46/NCR1 and its associated proteins underscores its pivotal role in regulating and augmenting the cytotoxic functions of activated NK cells, positioning it as a key player in immune surveillance and antitumor immunity.

Rat

HEK293

C-hFc

Q9Z0H5 (Q17-N255)

117547  [NCBI]

Approximately 65&36 kDa.

Greater than 95% as determined by reducing SDS-PAGE

<1 EU/μg, determined by LAL method.