1. Recombinant Proteins
  2. Others
  3. TLCD1 Protein, Human (Cell-Free, His)

TLCD1 Protein, Human (Cell-Free, His)

Cat. No.: HY-P702469
Handling Instructions

TLCD1 Protein intricately regulates plasma membrane dynamics by inhibiting the integration of omega-3 LCPUFA-enriched phospholipids, fostering membrane rigidity. Remarkably, TLCD1's influence is specific to membrane properties, showing no discernible impact on LCPUFA synthesis. This nuanced regulation establishes TLCD1 as a key player in preserving the structural integrity and functional balance of the plasma membrane. TLCD1 Protein, Human (Cell-Free, His) is the recombinant human-derived TLCD1 protein, expressed by E. coli Cell-free , with N-10*His labeled tag. The total length of TLCD1 Protein, Human (Cell-Free, His) is 212 a.a., with molecular weight of 26.1 kDa.

For research use only. We do not sell to patients.

Protein Expression Service

Size Stock
50 μg   Get quote  
100 μg   Get quote  

* Please select Quantity before adding items.

Top Publications Citing Use of Products
  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

TLCD1 Protein intricately regulates plasma membrane dynamics by inhibiting the integration of omega-3 LCPUFA-enriched phospholipids, fostering membrane rigidity. Remarkably, TLCD1's influence is specific to membrane properties, showing no discernible impact on LCPUFA synthesis. This nuanced regulation establishes TLCD1 as a key player in preserving the structural integrity and functional balance of the plasma membrane. TLCD1 Protein, Human (Cell-Free, His) is the recombinant human-derived TLCD1 protein, expressed by E. coli Cell-free , with N-10*His labeled tag. The total length of TLCD1 Protein, Human (Cell-Free, His) is 212 a.a., with molecular weight of 26.1 kDa.

Background

TLCD1 protein serves as a crucial regulator of plasma membrane dynamics by intricately modulating its composition and fluidity. Notably, TLCD1 exerts inhibitory control over the integration of membrane-fluidizing phospholipids enriched with omega-3 long-chain polyunsaturated fatty acids (LCPUFA), thereby fostering membrane rigidity. Interestingly, TLCD1's influence seems specific to membrane properties, as it does not manifest any discernible impact on the synthesis of LCPUFAs. This nuanced regulation positions TLCD1 as a key player in maintaining the structural integrity and functional balance of the plasma membrane.

Species

Human

Source

E. coli Cell-free

Tag

N-10*His

Accession

Q96CP7 (R36-E247)

Gene ID

116238

Molecular Construction
N-term
10*His
TLCD1 (R36-E247)
Accession # Q96CP7
C-term
Synonyms
TLC domain-containing protein 1; Calfacilitin
AA Sequence

RADPLRTWRWHNLLVSFAHSIVSGIWALLCVWQTPDMLVEIETAWSLSGYLLVCFSAGYFIHDTVDIVASGQTRASWEYLVHHVMAMGAFFSGIFWSSFVGGGVLTLLVEVSNIFLTIRMMMKISNAQDHLLYRVNKYVNLVMYFLFRLAPQAYLTHFFLRYVNQRTLGTFLLGILLMLDVMIIIYFSRLLRSDFCPEHVPKKQHKDKFLTE

Molecular Weight

26.1 kDa

Purity

Greater than 90% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

TLCD1 Protein, Human (Cell-Free, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
TLCD1 Protein, Human (Cell-Free, His)
Cat. No.:
HY-P702469
Quantity:
MCE Japan Authorized Agent: