TSSK2 Protein, Human (Sf9, GST)

The TSSK2 protein is a testis-specific serine/threonine protein kinase that is indispensable during late spermatogenesis and contributes to cytoplasmic remodeling. It is regulated by phosphorylating “Ser-288” of TSKS and SPAG16. TSSK2 Protein, Human (Sf9, GST) is the recombinant human-derived TSSK2 protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of TSSK2 Protein, Human (Sf9, GST) is 357 a.a., .

The TSSK2 protein, a testis-specific serine/threonine-protein kinase, plays an indispensable role in spermatid development, particularly in the late stages of spermatogenesis during cytoplasm reconstruction. It exerts its regulatory function by phosphorylating 'Ser-288' of TSKS and SPAG16. TSSK2's involvement is crucial for the intricate process of transforming a ring-shaped structure around the base of the flagellum, which originates from the chromatoid body. In the dynamic context of spermatogenesis, TSSK2 emerges as a key molecular player, orchestrating events that contribute to the structural and developmental changes necessary for the maturation of spermatids into fully functional sperm cells.

Human

Sf9 insect cells

N-GST

Q96PF2 (D2-T358)

23617

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.