2. GPCR/G Protein Neuronal Signaling
  3. Adrenergic Receptor
  4. Ritodrine hydrochloride

Ritodrine hydrochloride  (Synonyms: DU21220 hydrochloride)

Cat. No.: HY-B0452 Purity: 99.82%
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Ritodrine (DU21220) hydrochloride is a β-adrenergic agonist, also an effective smooth muscle and uterine relaxant. Ritodrine hydrochloride prolongs contraction interval, can be used for researching arrest premature labor.

For research use only. We do not sell to patients.

Ritodrine hydrochloride Chemical Structure

Ritodrine hydrochloride Chemical Structure

CAS No. : 23239-51-2

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Solid + Solvent
10 mM * 1 mL in DMSO
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 USD 87 In-stock
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Based on 2 publication(s) in Google Scholar

Other Forms of Ritodrine hydrochloride:

Ritodrine hydrochloride Related Antibodies

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Description

Ritodrine (DU21220) hydrochloride is a β-adrenergic agonist, also an effective smooth muscle and uterine relaxant. Ritodrine hydrochloride prolongs contraction interval, can be used for researching arrest premature labor[1][2][3].

Clinical Trial
Molecular Weight

323.81

Formula

C17H22ClNO3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OC1=CC=C(CCN[C@H](C)[C@@H](O)C2=CC=C(O)C=C2)C=C1.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 120 mg/mL (370.59 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : ≥ 100 mg/mL (308.82 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0882 mL 15.4412 mL 30.8823 mL
5 mM 0.6176 mL 3.0882 mL 6.1765 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% Saline

    Solubility: ≥ 1.71 mg/mL (5.28 mM); Clear solution

    This protocol yields a clear solution of ≥ 1.71 mg/mL (saturation unknown).

    Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (17.1 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.

    Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
  • Protocol 2

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in Saline)

    Solubility: ≥ 1.71 mg/mL (5.28 mM); Clear solution

    This protocol yields a clear solution of ≥ 1.71 mg/mL (saturation unknown).

    Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (17.1 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.

    Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 50 mg/mL (154.41 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / DMSO 1 mM 3.0882 mL 15.4412 mL 30.8823 mL 77.2058 mL
5 mM 0.6176 mL 3.0882 mL 6.1765 mL 15.4412 mL
10 mM 0.3088 mL 1.5441 mL 3.0882 mL 7.7206 mL
15 mM 0.2059 mL 1.0294 mL 2.0588 mL 5.1471 mL
20 mM 0.1544 mL 0.7721 mL 1.5441 mL 3.8603 mL
25 mM 0.1235 mL 0.6176 mL 1.2353 mL 3.0882 mL
30 mM 0.1029 mL 0.5147 mL 1.0294 mL 2.5735 mL
40 mM 0.0772 mL 0.3860 mL 0.7721 mL 1.9301 mL
50 mM 0.0618 mL 0.3088 mL 0.6176 mL 1.5441 mL
60 mM 0.0515 mL 0.2574 mL 0.5147 mL 1.2868 mL
80 mM 0.0386 mL 0.1930 mL 0.3860 mL 0.9651 mL
100 mM 0.0309 mL 0.1544 mL 0.3088 mL 0.7721 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Ritodrine hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ritodrine23239-51-2DU21220DU 21220DU-21220Adrenergic ReceptorBeta ReceptorInhibitorinhibitorinhibit

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