2. MAPK/ERK Pathway
  3. p38 MAPK
  4. SB 203580 sulfone

SB 203580 sulfone is an analog of p38 MAP kinase inhibitor SB 203580, which inhibits the IL-1 production in monocytes with an IC50 of 0.2 μM and binds competitively with CSAID binding proteins (CSBP), inhibits it mediated stress response signaling with an IC50 of 0.03 μM.

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SB 203580 sulfone Chemical Structure

SB 203580 sulfone Chemical Structure

CAS No. : 152121-46-5

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SB 203580 sulfone Related Antibodies

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Description

SB 203580 sulfone is an analog of p38 MAP kinase inhibitor SB 203580, which inhibits the IL-1 production in monocytes with an IC50 of 0.2 μM and binds competitively with CSAID binding proteins (CSBP), inhibits it mediated stress response signaling with an IC50 of 0.03 μM[1].

Molecular Weight

393.43

Formula

C21H16FN3O2S
CAS No.
SMILES

O=S(C1=CC=C(C2=NC(C3=CC=C(F)C=C3)=C(C4=CC=NC=C4)N2)C=C1)(C)=O
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Room temperature in continental US; may vary elsewhere.
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Purity & Documentation
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SB 203580 sulfone Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SB 203580 sulfone152121-46-5p38 MAPKTHPInhibitorinhibitorinhibit

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