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Results for "

Ac-​IETD-​CHO

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

4

Peptides

1

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-120833

    Caspase Others
    Ac-Ile-Glu-Thr-Asp-pNA is a substrate for caspase-8. Caspase-8 binds to and cleaves the Ile-Glu-Thr-Asp (IETD) peptide sequence to release p-nitroalinide, which can be quantified by colorimetric detection at 405 nm as a measure of enzyme activity .
    Ac-Ile-Glu-Thr-Asp-pNA
  • HY-113963

    Apoptosis Cancer
    Ac-?IETD-?CHO is a potent, reversible inhibitor of granzyme B and caspase-8. Ac-?IETD-?CHO inhibits Fas-mediated apoptotic cell death, hemorrhage, and liver failure. Ac-?IETD-?CHO also inhibits cytotoxic T lymphocytes induced cell death .
    <em>Ac-​IETD</em>-​CHO
  • HY-N12840

    Others Metabolic Disease
    Logmalicid B is an iridoid glycoside compound that can be isolated from Cornus officinalis and can be used in diabetes research .
    Logmalicid B
  • HY-P10001

    Z-Ile-Glu-Thr-Asp-pNA

    Caspase Cancer
    Z-IETD-pNA (Z-Ile-Glu-Thr-Asp-pNA) is a colorimetric caspase-8 and granzyme B substrate. Z-IETD-pNA is hydrlyzed by caspase 8 to generate pNA .
    Z-<em>IETD</em>-pNA
  • HY-P10322

    Fluorescent Dye Inflammation/Immunology
    Z-IETD-R110 is a fluorescent substrate of caspases. Z-IETD-R110 acts as a substrate for caspase-8. When caspase-8 is activated, it can recognize and cut Z-IETD-R110, releasing fluorophore, which can be detected by fluorescence microscopy. Z-IETD-R110 can be used to study oxidative stress-induced apoptosis, particularly in pancreatic acinar cells .
    Z-<em>IETD</em>-R110

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