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Results for "

Cl-amidine

" in MedChemExpress (MCE) Product Catalog:

9

Inhibitors & Agonists

1

Peptides

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-100574A
    Cl-amidine hydrochloride
    Maximum Cited Publications
    10 Publications Verification
    Cl-amidine hydrochloride is an orally active peptidylarginine deminase (PAD) inhibitor, with IC50 values of 0.8 μM, 6.2 μM and 5.9 μM for PAD1, PAD3, and PAD4, respectively. Cl-amidine hydrochloride induces apoptosis in cancer cells. Cl-amidine hydrochloride induces microRNA (miR)-16 (miRNA-16, microRNA-16) expression and causes cell cycle arrest. Cl-Amidine hydrochloride prevents histone 3 citrullination and neutrophil extracellular trap formation, and improves survival in a murine sepsis model .
    <em>Cl-amidine</em> hydrochloride
  • HY-100574D
    D-Cl-amidine hydrochloride

    		Protein Arginine Deiminase Apoptosis Cancer
    D-Cl-amidine hydrochloride is a potent and highly selective PAD1 inhibitor. D-Cl-amidine is well-torelated with no significant toxicity .
    D-<em>Cl-amidine</em> hydrochloride
  • HY-100574
    Cl-amidine

    Cl-amidine is an orally active peptidylarginine deminase (PAD) inhibitor, with IC50 values of 0.8 μM, 6.2 μM and 5.9 μM for PAD1, PAD3, and PAD4, respectively. Cl-amidine induces apoptosis in cancer cells. Cl-amidine induces microRNA (miR)-16 (miRNA-16, microRNA-16) expression and causes cell cycle arrest. Cl-Amidine prevents histone 3 citrullination and neutrophil extracellular trap formation, and improves survival in a murine sepsis model .
    <em>Cl-amidine</em>
  • HY-100574B
    Cl-amidine TFA

    		Protein Arginine Deiminase Apoptosis MicroRNA Inflammation/Immunology Cancer
    Cl-amidine TFA is an orally active peptidylarginine deminase (PAD) inhibitor, with IC50 values of 0.8 μM, 6.2 μM and 5.9 μM for PAD1, PAD3, and PAD4, respectively. Cl-amidine TFA induces apoptosis in cancer cells. Cl-amidine TFA induces microRNA (miR)-16 (miRNA-16, microRNA-16) expression and causes cell cycle arrest. Cl-Amidine TFA prevents histone 3 citrullination and neutrophil extracellular trap formation, and improves survival in a murine sepsis model .
    <em>Cl-amidine</em> TFA
  • HY-100574C
    D-Cl-amidine

    		Protein Arginine Deiminase Apoptosis Inflammation/Immunology Cancer
    D-Cl-amidine is a potent and highly selective PAD1 inhibitor. D-Cl-amidine is well-torelated with no significant toxicity .
    D-<em>Cl-amidine</em>
  • HY-111347
    BB-Cl-Amidine

    		Protein Arginine Deiminase Inflammation/Immunology
    BB-Cl-Amidine is a peptidylarginine deminase (PAD) inhibitor.
    BB-<em>Cl-Amidine</em>
  • HY-111347A
    BB-Cl-Amidine hydrochloride
    3 Publications Verification

    		 Protein Arginine Deiminase Inflammation/Immunology
    BB-Cl-Amidine hydrochloride is a peptidylarginine deminase (PAD) inhibitor .
    BB-<em>Cl-Amidine</em> hydrochloride
  • HY-156117
    LB244

    		STING Cancer
    LB244 is a homologue of BB-Cl-amidine, which is an orally effective STING inhibitor (EC50=0.8 μM) and can be used to inhibit STING-dependent inflammatory diseases. The pharmacokinetic properties of LB244 indicate limited oral activity in mice .
    LB244
  • HY-P1182
    C21

    		Histone Methyltransferase Cancer
    C21 is a potent, irreversible, and selective PRMT1 inhibitor with an IC50 of 1.8 μM. C21 inhibits PRMT6 with an IC50 of 8.8 μM .
    C21

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