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Results for "

Filgotinib

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

1

Fluorescent Dye

1

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-18300
    Filgotinib
    Maximum Cited Publications
    16 Publications Verification

    GLPG0634

    		 JAK Cancer
    Filgotinib (GLPG0634) is a selective and orally active JAK1 inhibitor with IC50 of 10 nM, 28 nM, 810 nM, and 116 nM for JAK1, JAK2, JAK3, and TYK2, respectively.
    <em>Filgotinib</em>
  • HY-102055
    JAK2 JH2 Tracer
    4 Publications Verification

    		 JAK Others
    JAK2 JH2 Tracer (Tracer 5) is a fluorescent probe for JAK2 JH2 domain, with a Kd of value 0.2 μM .
    JAK2 JH2 Tracer
  • HY-W394903
    GS-829845

    		JAK Drug Metabolite Cancer
    GS-829845 is a major, active metabolite of Filgotinib (HY-18300). GS-829845 is a JAK1 preferential inhibitor but is approximately 10-fold less potent than the parent and with a longer half-life .
    GS-829845
  • HY-18300A
    Filgotinib maleate

    GLPG0634 maleate

    		 JAK Inflammation/Immunology
    Filgotinib (maleate) is a selective and orally active JAK1 inhibitor with IC50 of 10 nM, 28 nM, 810 nM and 116 nM for JAK1, JAK2, JAK3 and TYK2, respectively. Filgotinib (maleate) can be used for rheumatoid arthritis (RA) and Crohn's disease research .
    <em>Filgotinib</em> maleate
  • HY-18300S
    Filgotinib-d4

    GLPG0634-d4

    		 JAK Cancer
    Filgotinib-d4 is the deuterium labeled Filgotinib. Filgotinib (GLPG0634) is a selective JAK1 inhibitor with IC50 of 10 nM, 28 nM, 810 nM, and 116 nM for JAK1, JAK2, JAK3, and TYK2, respectively.
    <em>Filgotinib</em>-d4

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