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HDAC3-IN-1

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-18712
    BG45
    2 Publications Verification

    		 HDAC Apoptosis Caspase Cancer
    BG45 is a potent HDAC3 inhibitor with IC50 values of 0.289, 2, 2.2 and ﹥20 μM for HDAC3, HDAC1, HDAC2 and HDAC6, respectively. BG45 selectively targets multiple myeloma (MM) cells and induces caspase-dependent apoptosis .
    BG45
  • HY-117374
    HDAC3-IN-1

    		HDAC Cancer
    HDAC3-IN-1 (compound 5) is a potent and selective HDAC3 inhibitor, with an IC50 of 5.96 nM .
    <em>HDAC3-IN-1</em>
  • HY-14842A
    Givinostat hydrochloride

    ITF-2357 hydrochloride

    		 HDAC Cancer
    Givinostat (ITF-2357) hydrochloride is a HDAC inhibitor with an IC50 of 198 and 157 nM for HDAC1 and HDAC3, respectively .
    Givinostat hydrochloride
  • HY-W014004
    m-Carboxycinnamic acid bishydroxamide

    CBHA

    		 HDAC Cancer
    m-Carboxycinnamic acid bishydroxamide is a potent HDAC inhibitor, exhibiting ID50 values of 10 and 70 nM in vitro for HDAC1 and HDAC3, respectively . m-Carboxycinnamic acid bishydroxamide also induces apoptosis and suppresses tumor growth .
    m-Carboxycinnamic acid bishydroxamide

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