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KPT-8602

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-100423
    Eltanexor
    1 Publications Verification

    KPT-8602
    Eltanexor (KPT-8602) is a second-generation, highly specific and orally active exportin-1 (XPO1) inhibitor with potent anti-leukemic activity. Eltanexor (KPT-8602) inhibits XPO1-dependent nuclear export (EC50=60.9 nM) by directly targeting XPO1. Eltanexor (KPT-8602) induces Caspase-dependent apoptosis in a panel of leukemic cell lines .
    Eltanexor
  • HY-100423A
    Eltanexor Z-isomer
    1 Publications Verification

    KPT-8602 (Z-isomer)

    		 CRM1 Cancer
    Eltanexor Z-isomer (KPT-8602 Z-isomer) is the less active isomer of KPT-8602.
    Eltanexor Z-isomer

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