Search Result
Results for "
Saponin
" in MedChemExpress (MCE) Product Catalog:
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-100597
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Saponin
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Fungal
Bacterial
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Inflammation/Immunology
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Saponins (Saponin) is a class of chemical compound of glycosides found in particular abundance in various plant species. In plants, Saponins may serve as anti-feedants, and to protect the plant against microbes and fungi .
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- HY-N5055
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Others
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Others
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Saponin C, from Liriope muscari is isolated from Liriope muscari.
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- HY-107233
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Prosapogenin CP4
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Others
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Others
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Saponin CP4 is an oleanolic acid derivative which lacks a 23-OH. Saponin CP4 shows no growth inhibition .
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- HY-107235
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Clematoside S; Prosapogenin CP6
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Others
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Others
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Saponin CP6 is a triterpenoid compound from the roots of Clematis grata .
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- HY-N7974
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Others
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Others
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Kizuta saponin K11 is a saponin found in the leaves of Kalopanax pictum var. maximowiczii, a Korean medicinal plant .
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- HY-N11034
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Others
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Others
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24-Hydroxy-licorice-saponin A3 is an oleanane-type triterpene saponin (OTS). 24-Hydroxy-licorice-saponin A3 can be isolated from G. uralensis. .
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- HY-N3584
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Chonglou Saponin VII
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Akt
p38 MAPK
P-glycoprotein
Bcl-2 Family
Caspase
PARP
Autophagy
Apoptosis
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Cancer
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Paris saponin VII (Chonglou Saponin VII) is a steroidal saponin isolated from the roots and rhizomes of Trillium tschonoskii. Paris saponin VII-induced apoptosis in K562/ADR cells is associated with Akt/MAPK and the inhibition of P-gp. Paris saponin VII attenuates mitochondrial membrane potential, increases the expression of apoptosis-related proteins, such as Bax and cytochrome c, and decreases the protein expression levels of Bcl-2, caspase-9, caspase-3, PARP-1, and p-Akt. Paris saponin VII induces a robust autophagy in K562/ADR cells and provides a biochemical basis in the treatment of leukemia .
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- HY-N9332
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Others
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Others
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Kalopanax saponin G is an ester glycoside of oleanolic acid possessing no sugar moiety at the C-3 hydroxyl group. Kalopanax saponin G is isolated from the bark of Kalopanax pictus .
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- HY-N4229
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Others
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Others
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Clematomandshurica saponin C is found in Clematis manshurica .
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- HY-N4230
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COX
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Inflammation/Immunology
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Clematomandshurica saponins B shows significant inhibitory activity on cyclooxygenase-2 (IC50=2.58 mM) .
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- HY-N6068
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Hederacolchiside F
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Others
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Others
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Pulsatilla saponin H is a natural compound isolated from the Roots of Pulsatilla koreana .
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- HY-N6911
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(18β,20α)-Glycyrrhizic acid
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Others
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Metabolic Disease
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Licorice-saponin H2 ((18β,20α)-Glycyrrhizic acid) is a saponin from Glycyrrhiza uralensis Fischer .
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- HY-N0834
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SB365; Hederacolchiside A
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Apoptosis
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Cancer
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Pulsatilla saponin D (SB365), isolated from the root of Pulsatilla chinensis, is an anti-tumor agent .
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- HY-N10074
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Others
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Others
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Polygalacin D2 is a saponin isolated from Platycodon grandiflorum .
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- HY-N11448
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- HY-N12152
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Others
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Others
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Molluscicidal agent-1 (Compound 3) is a saponin that can be isolated from S.vesicaria .
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- HY-N7952
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Others
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Others
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Achyranthoside D is a triterpene saponin from Achyranthes root .
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- HY-N2386
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Others
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Others
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Polyphyllin E is a steroidal saponin that can be isolated from Paris polyphylla .
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- HY-N12355
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Others
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Others
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Disporoside C is a steroidal saponin can be isolated from Disporopsis pernyi .
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- HY-N4272
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Others
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Cancer
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Protodeltonin is a steroidal saponin from Dioscorea zingiberensis Wright, with anti-proliferation activity .
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- HY-N2516
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- HY-N11923
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Others
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Others
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Lysimachigenoside C is a triterpene saponin isolated from Lysimachia foenum-graecum Hance .
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- HY-N11810
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Others
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Others
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Polyfuroside is a triterpenoid saponin, which can be isolated from the defatted rhizome of jade bamboo .
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- HY-N12065
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Others
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Others
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Parisyunnanoside H is a steroidal saponin isolated from Paris polyphylla Smith var. yunnanensis .
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- HY-16941
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Others
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Cancer
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Damulin A is a saponin found in G. pentaphyllum with anti-cancer activities .
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- HY-N8235
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Others
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Others
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Virgaureagenin F is a saponin that can be extracted from the rhizoma bolbostemmae .
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- HY-N2046
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Jujuboside A1
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Others
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Others
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Jujuboside D (Jujuboside A1) is a dammarane-type saponin that can be isolated from the seeds of Ziziphus jujube .
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- HY-N8662
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- HY-N12148
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Others
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Others
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Macrostemonoside I is a furostanol saponin that can be isolated from Allium macrostemon .
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- HY-N4262
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Others
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Others
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Ginsenoside Rh7 is a minor saponin isolated from the leaves of Panax ginseng .
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- HY-N4217
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Others
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Others
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Saikosaponin I is a triterpene saponin extracted from Bupleurum falcatum L. Saikosaponin can be used to treat fever, inflammation, liver disease, and nephritis .
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- HY-N12533
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Others
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Others
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Quinquenoside R1 (Compound 12) is a saponin compound that can be isolated from wild ginseng .
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- HY-N12292
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- HY-W019830
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Others
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Others
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Polyphyllin F is a diosgenyl saponin that can be found in Paris polyphylla .
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- HY-N8215
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Others
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Metabolic Disease
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Achyranthoside C is a saponin from Achyranthes bidentata. The derivative of Achyranthoside C has inhibitory activity on osteoclast formation .
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- HY-N8410
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Others
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Others
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Momordicoside P is a cucurbitane-type triterpenoid saponin. Momordicoside P can be isolated from the fresh fruits of Momordica charantia .
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- HY-N8901
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- HY-N12587
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- HY-125686
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Others
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Others
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Beesioside Q is a oleanolic acid triterpene saponin isolated from the rhizome of Beesia calthaefolia (Maxim.) Ulbr .
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- HY-107242
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Others
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Others
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Raddeanoside R8 is a saponin that can be isolated from fresh rhizoma of Anemone raddeana Regel .
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- HY-N8112
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Others
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Others
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Polygalasaponin LII is a triterpenoid saponin that ca n be isolated from the roots of Polygala japonica Houtt .
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- HY-N12298
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Others
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Others
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Ciwujianoside C1 is a saponin, that can be isolated from the leaves of Acanthopanax senticosus. Ciwujianoside C1 inhibits pancreatic lipase activity in vitro .
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- HY-N8922
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Others
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Others
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Platycodin A is monoacetylated saponin compound isolated fromhe roots of Platycodon grandiflorum A. DC. .
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- HY-107236
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Others
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Others
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Huzhangoside D is a saponin compound isolated from the roots and rhizomes of Clematis graveolens .
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- HY-N4064
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Others
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Others
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Hederagenic acid (compound 2) is a kind of triterpenoid saponin. Hederagenic acid can be isolated from the roots of Kalopanax septemlobus (Thunb.) Koidz .
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- HY-N4264
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Others
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Inflammation/Immunology
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Vinaginsenoside R3 is a saponin composition of roots of Panax ginseng. Ginsengs have been not only used as therapeutic agents with tonic, anti-fatigue, and anti-gastric ulcer effect but also marketed as dietary supplements and raw materials of health food .
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- HY-N11073
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Others
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Others
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Clematiganoside A is a triterpenoid saponin that can be isolatred from Clematis ganpiniana .
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- HY-N1439
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Gypsogenin-3-O-(6-O-methyl)-glucoside
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Others
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Inflammation/Immunology
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Methyl gypsogenin-3-O-glucuronide (Gypsogenin-3-O-(6-O-methyl)-glucoside) is a ubiquitous saponin precursor in plants of the genus Gypsophila .
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- HY-N8116
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Others
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Others
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Leonloside D is a Hederagenin-derived saponin, composed of a molecule of Hederagenin and 1-3 molecules of rhamnose, glucose, or arabinose .
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- HY-N9490
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Others
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Others
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Phytolaccagenic acid is the main composition of quinoa saponin. Phytolaccagenic acid is an active compound. Phytolaccagenic acid can be used for the research of various biochemical .
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- HY-N11983
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Others
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Others
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(25R)-Ruscogenin-3-yl α-L-rhamnopyranosyl-(1→2)-[β-D-xylopyranosyl-(1→4)]-β-D-glucopyranoside (compound 1) is a steroidal saponin , can be isolated from the roots of Ophiopogon japonicus .
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- HY-N12272
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Acetyl-soyaSaponin A2
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Others
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Others
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Soyasaponin Af (Acetyl-soyasaponin A2) is a saponin isolated from Black bean (Phaseolus vulgaris L.) seed coats .
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- HY-N11068
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Others
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Others
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Huzhangoside C is a oleanane-type triterpenoid saponin that can be isolated from the roots of Clematis argentilucida .
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- HY-N12190
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Others
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Others
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Centellasaponin A (compound 10) is a pentacyclic triterpene saponin isolated from the methanolic extract of Centella asiatica .
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- HY-N8096
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Pulchinenoside E3
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Others
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Inflammation/Immunology
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Raddeanoside R17 (Pulchinenoside E3) is a saponin compound that can be isolated from the root of Pulsatilla koreana. Raddeanoside R17 shows anti-inflammatory effects .
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- HY-N5135
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Nolinospiroside F
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Others
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Others
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Liriopesides B (Nolinospiroside F) is a steroidal saponin isolated from Ophiopogon japonicas. Liriopesides B has anti-oxidative and anti-aging effects .
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- HY-N8098
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Others
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Cancer
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Pulchinenoside E2 (Compound 8) is a triterpene saponin isolated from the roots of Pulsatilla chinensis. Pulchinenoside E2 shows cytotoxic to HL-60 cells with an IC50 value of 2.6 µg/mL .
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- HY-N7614
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SchidigeraSaponin F2; TimoSaponin AII
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Others
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Cardiovascular Disease
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Anemarrhenasaponin A2 (Schidigerasaponin F2) is a steroidal saponin isolated from the rhizomes of Anemarrhena asphodeloides. Anemarrhenasaponin A2 inhibits ADP-induced platelet aggregation .
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- HY-N8610
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Phosphatase
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Inflammation/Immunology
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Uralsaponin D is a saponin that can be isolated from Glycyrrhiza inflata. Uralsaponin D inhibits phospholipase A2 (PLA2) with an IC50 value of 32.2 μM .
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- HY-N8763
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Guaianin A
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Others
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Neurological Disease
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Ciwujianoside E is a triterpene saponin that can be isolated from Acanthopanax senticosus. Ciwujianoside E can be used in study sedative-hypnotic drug .
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- HY-W019829
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Tyrosinase
Parasite
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Infection
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Polyphyllin C (compound 2) is a spirostanol saponin. Polyphyllin C exhibits mild (IC50=36.87 µM) activities against the tyrosinase and moderate (IC50=1.59 µg/mL) antileishmanial activities .
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- HY-N8609
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Others
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Others
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Uralsaponin C is an analogue of oleanane-type triterpenoid saponin. Uralsaponin C can be isolated from the roots of Glycyrrhiza uralensis Fisch .
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- HY-N3323
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Others
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Inflammation/Immunology
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Mannioside A is a steroidal saponin. Mannioside A is a nature product that could be isolated from Dracaena mannii. Mannioside A has anti-inflammatory effect .
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- HY-N11433
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Others
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Others
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Celosin L is a triterpenoid saponin with hepaprotective activity. Celosin L exhibits protective effects against APAP-induced hepatotoxicity in HepG2 cells .
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- HY-16942
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Apoptosis
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Cancer
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Damulin B is a dammarane-type saponin found in Gynostemma pentaphyllum.Damulin B can induce cell apoptosis and has anti-cancer activities in vitro .
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- HY-N8810
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Others
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Others
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Platycoside M1 is a A-ring lactone triterpenoid saponin that can be isolaoted from the roots of Platycodon grandiflorum. Platycosides are the main active constituents of P. grandiflorus with multiple pharmacological activities .
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- HY-N0797
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- HY-N9324
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Xanthine Oxidase
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Inflammation/Immunology
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Ilexoside O is a triterpene saponin isolated from the roots of Ilex pubescens. Ilexoside O exhibits weak xanthine oxidase (XOD) inhibitory activity (IC50=53.05 μM) .
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- HY-N8804
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Asparanin B
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Reactive Oxygen Species
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Neurological Disease
Cancer
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Shatavarin IV is a steroidal saponin, that can be isolated from the roots of Asparagus racemosus (Liliaceae). Shatavarin IV shows anticancer activity. Shatavarin IV elicits lifespan extension and alleviates Parkinsonism in Caenorhabditis elegans .
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- HY-N6058
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Parasite
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Others
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(3β)-3-[(O-β-D-Glucopyranosyl-(1→3)-O-6-deoxy-α-L-mannopyranosyl-(1→2)-α-L-arabinopyranosyl)oxy]olean-12-en-28-oic acid is a member of Oleanolic acid saponins with trematocide activity .
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- HY-N12016
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Others
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Metabolic Disease
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Fulvotomentoside B is a saponin isolated from Lactobacillus flavus. Fulvotomentoside compounds can significantly reduce serum glutamate pyruvate transaminase (SGPT) and triacylglycerol (GT) levels in mice poisoned by CCl4, d-galactosamine (d-gal) and acetaminophen, and significantly alleviate liver pathology. damage .
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- HY-N1411
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AMPK
Wnt
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Metabolic Disease
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Platycodin D is a saponin isolated from Platycodon grandiflorus, acts as an activator of AMPKα, with anti-obesity property. WNT/β-catenin pathway mediates the anti-adipogenic effect of platycodin D .
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- HY-N6256
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Phosphodiesterase (PDE)
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Cardiovascular Disease
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Ilexsaponin B2 is a saponin isolated from the root of Ilex pubescens Hook. et Arn. Ilexsaponin B2 is a potent phosphodiesterase 5 (PDE5) and PDEI inhibitor with IC50 values of 48.8 μM and 477.5 μM, respectively .
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- HY-N7273
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Apoptosis
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Cancer
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Soyasaponin III, a monodesmodic oleanane triterpenoid, is one of the main potentially bioactive saponins found in soy (Glycine max) and related products. Soyasaponin III can induce apoptosis in Hep-G2 cells .
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- HY-N12225
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Others
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Neurological Disease
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Isoasiaticoside is a pentacyclic triterpene saponin that can be isolated from Centella asiatica. Isoasiaticoside has potential neuroprotective effects in the 6-OHDA (HY-B1081)-induced PC12 cell model .
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- HY-N7687
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PPAR
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Metabolic Disease
Inflammation/Immunology
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Caulophyllogenin is a triterpene saponin extracted from M. polimorpha. Caulophyllogenin is a partial PPARγ agonist, with an EC50 of 12.6 μM. Caulophyllogenin can be used for the research of type-2 diabetes, obesity, metabolic syndrome and inflammation .
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- HY-N12137
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Others
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Cancer
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Glycoside St-J (Compound 2) is a triterpenoid saponin. Glycoside St-J has antitumor activity and inhibits HeLa cell proliferation. Glycoside St-J Isolates from natural Anemone flaccida. Glycoside St-J can be used in the development of new anticancer agents .
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- HY-N2109
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Others
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Metabolic Disease
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Macranthoidin A is an orally active saponin from Flos Lonicerae. Macranthoidin A possess protection effects on hepatic injury caused by Acetaminophen, Cd, and CCl4, and conspicuous depressant effects on swelling of ear croton oil .
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- HY-125570
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Apoptosis
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Cancer
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Ginsenoside Rs3 is a natural diol-type ginseng saponin with anticancer effects. Ginsenoside Rs3 selectively elevates protein levels of p53 and p21WAF1 leading to induction of apoptosis in SK-HEP-1 cells .
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- HY-N12128
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Others
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Cancer
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Ophiopogonin R (compound 3) is a steroid saponin. Ophiopogonin R was isolated and purified from natural ophiopogonin. Ophiopogonin R was not cytotoxic to five human tumor cell lines (HepG2, HLE, BEL7402, BEL7403 and Hela) .
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- HY-N8211
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p38 MAPK
ERK
NF-κB
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Inflammation/Immunology
Cancer
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Gypenoside L is a saponin that can be found in Gynostemma pentaphyllum. Gypenoside L increases the SA-β-galactosidase activity, promotes the production of senescence-associated secretory cytokines. Gypenoside L also can activate p38 and ERK MAPK pathways and NF-κB pathway to induce senescence. Gypenoside L exhibits anti-tumor and anti-inflammatory activities .
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- HY-N12002
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Others
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Others
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Diosgenin-3-O-rhamnosyl(1→2)[glucosyl(1→6)]glucoside (compound 9) is a steroidal saponin, which can be obtained from Paris polyphylla var., Yunnan pine (yunnanensis) Isolated .
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- HY-N0615
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Sanchinoside R1; Sanqi glucoside R1
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Amyloid-β
Apoptosis
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Others
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Notoginsenoside R1 (Sanchinoside R1), a saponin, is isolated from P. notoginseng. Notoginsenoside R1 exhibits anti-oxidation, anti-inflammatory, anti-angiogenic, and anti-apoptosis activities. Notoginsenoside R1 provides cardioprotection against ischemia/reperfusion (I/R) injury. Notoginsenoside R1 also provides neuroprotection in H2O2-induced oxidative damage in PC12 cells .
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- HY-N0863
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NSC-698790; Smilax Saponin B
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Apoptosis
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Cancer
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Methyl protodioscin(NSC-698790) is a furostanol bisglycoside with antitumor properties; shows to reduce proliferation, cause cell cycle arrest.
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- HY-N0864
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Macranthoiside I
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Others
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Cancer
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Macranthoidin B is a major bioactive saponin in rat plasma after oral administration of extraction of saponins from Flos Lonicerae.
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- HY-107309
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Others
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Cancer
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Scabioside C is a main triterpenoid saponin for total secondary saponin (TSS). TSS, from A. raddeana, exhibits the potential anti-breast cancer effect .
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- HY-N0345
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Others
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Inflammation/Immunology
Cancer
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Liriope muscari baily saponins C is one of major active compounds of L. muscari (Decne.) Baily. Liriope muscari baily saponins C possesses strong anti-inflammatory, immunopharmacological and cardioprotective activities. Liriope muscari baily saponins C has been studied as a candidate agent for cancer metastasis .
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- HY-N8216
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- HY-N12290
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- HY-N4271
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Others
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Cardiovascular Disease
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Protogracillin is a steroidal saponin isolated from Dioscorea zingiberensis Wright (DZW). Steroidal saponins from DZW rhizomes have the potential to reduce the risk of cardiovascular diseases by anti-thrombotic action .
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- HY-N7966
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- HY-N8222
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- HY-N9373
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- HY-N4270
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Others
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Others
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Pseudoprotogracillin is a steroidal saponin isolated Dioscoreae species .
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- HY-N0302
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- HY-107284
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Others
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Others
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Officinalisinin I is a steroidal saponin, isolated from Anemarrhena asphodeloides.
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- HY-N6265
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Others
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Others
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Cauloside F is a triterpenoid saponin isolated from Clematis akebioides.
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- HY-N5087
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Others
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Others
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Nudicaucin A is a triterpenoid saponin isolated from Hedyotis nudicaulis .
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- HY-N9989
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Others
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Others
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Brachyoside B is a triterpenoid saponin from Astragalus wiedemannianus .
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- HY-N7235
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Others
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Cancer
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Lanatoside E is a cyclic triterpene saponin with antitumor activity .
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- HY-N0206
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Deglucocyclamin; LTS-4; Saxifragifolin B
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Antibiotic
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Cancer
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Ardisiacrispin A (Deglucocyclamin) is a common triterpenoid saponin from Ardisia species. Ardisiacrispin A has similar biological properties with some triterpenoid saponins in A. crenata which is one of the species of genus Ardisia and exhibits cytotoxic effect on tumor cells, immunomodulatory and antiviral activities .
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- HY-N0266
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- HY-N6982
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- HY-N2606
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- HY-107314
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Others
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Others
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Pulchinenoside B is a triterpenoid saponin isolated from Pulsatilla chinensis .
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- HY-N5071
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Others
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Others
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Clematichinenoside C is one of triterpenoid saponins found in Clematis parviloba .
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- HY-N12383
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Others
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Others
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Officinalisnin-II is a natural saponin found in the roots of Asparagus filicinus .
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- HY-N0910
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- HY-N4135
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Others
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Metabolic Disease
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Acanthopanaxoside B is a triterpenoid saponin isolated from the leaves of Acanthopanax senticosus .
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- HY-107300
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SoyaSaponin Be methyl ester; DHS-I methyl ester
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Others
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Others
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Dehydrosoyasaponin I methyl ester (Soyasaponin Be methyl ester) is a saponin found in Trifolium alexandrinum .
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- HY-N6079
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Others
|
Others
|
Timosaponin A1 is a coprostane type steroidal saponin isolated from Rhizoma Anemarrhenae.
|
-
- HY-N1479
-
|
Others
|
Others
|
Polygalic acid, a triterpenoid saponin, is considered one of the major active constituents of Polygala tenuifolia .
|
-
- HY-N3520
-
-
- HY-N1932
-
|
Others
|
Metabolic Disease
|
Bayogenin is an alfalfa saponin, shows moderate potency of glycogen phosphorylase inhibition .
|
-
- HY-N2001
-
-
- HY-N6970
-
Congmunoside V
|
Others
|
Metabolic Disease
|
Araloside V (Congmunoside V) is a triterpenoid saponin isolated from Aralia elata .
|
-
- HY-N7919
-
|
Others
|
Metabolic Disease
|
Celosin H is a hepatoprotective triterpenoid saponin that can be isolated from Celosiae Semen .
|
-
- HY-N2002
-
Congmunoside VII
|
Others
|
Others
|
Araloside VII (Congmunoside VII) is a saponin isolated from leaves of Aralias elate .
|
-
- HY-N12293
-
|
Others
|
Others
|
Yemuoside YM12 is a nortriterpenoid saponin, that can be found in Stauntonia chinensis Decne .
|
-
- HY-N12578
-
|
Others
|
Others
|
Polygalasaponin XXVIII is a triterpenoid saponin that can be isolated from Polygala japonica Houtt. .
|
-
- HY-N4087
-
|
Others
|
Cancer
|
Platycodin D2 is a saponin isolated from Platycodon grandiflorum, with anti-cancer activity .
|
-
- HY-N0588
-
|
HCV
|
Infection
|
Deapioplatycodin D is a triterpenoid saponin isolated from Platycodon grandiflorum, with anti-HCV activity .
|
-
- HY-133237
-
|
Others
|
Others
|
Anemarrhenasaponin III is a steroidal saponin isolated from the rhizome of Anemarrhena asphodeloides Bunge (Liliaceae) .
|
-
- HY-N12294
-
-
- HY-N12296
-
-
- HY-N12424
-
|
Others
|
Others
|
Elephanoside D (compound 8) is a steroidal saponin isolated from the stems of Yucca elephantipes Regel.
|
-
- HY-N3519
-
|
HCV
|
Infection
|
Platycodin D3 is a triterpenoid saponin isolated from Platycodon grandiflorum, with anti-HCV activity .
|
-
- HY-N6088
-
|
Others
|
Others
|
Isoginsenoside-Rh3 is a triterpenoid saponin from the fruits of Panax ginseng C. A. Mey .
|
-
- HY-125702
-
Chinensioside B
|
Others
|
Others
|
Pulsatilloside E (Chinensioside B) is a triterpenoidal saponin isolated from the roots of Pulsatilla chinensis (Ranunculaceae) .
|
-
- HY-N10414
-
PrimulaSaponin 1; Primula acid I
|
Others
|
Others
|
Primulic acid I (Primulasaponin 1) is a plant-derived triterpenoid saponin with one sugar chain (monodesmoid) .
|
-
- HY-N11452
-
|
Others
|
Others
|
Cernuoside B is a natural triterpenoid saponin that can be isolated from the roots of Pulsatilla koreana Nakai .
|
-
- HY-N11458
-
|
Others
|
Others
|
Raddeanoside R16 is an oleanane-type saponin, that can be isolated from the rhizoma of Anemone raddeana .
|
-
- HY-125121
-
-
- HY-N11115
-
|
Others
|
Others
|
Macedonoside A (compound 3) is a kind of saponin. Macedonoside A can be isolated from the stolons of Glycyrrhiza lepidota .
|
-
- HY-N0818
-
Calenduloside F
|
Others
|
Others
|
Chikusetsusaponin IVa a major active ingredient of triterpenoid saponins, exerts antithrombotic effects, including minor hemorrhagic events.
|
-
- HY-N0254
-
|
Others
|
Inflammation/Immunology
|
Hederacoside D is one of the bioactive saponins from Hedera helix, and plays pivotal roles in the overall biological activity.
|
-
- HY-N5078
-
|
Others
|
Cardiovascular Disease
|
Terrestrosin K, a steroidal saponin from Tribulus terrestris L., has potential to treat cardiovascular and cerebrovascular diseases .
|
-
- HY-107311
-
|
Others
|
Others
|
Hederacholchiside E (compound 6) is a kind of saponin. Hederacholchiside E can be isolated from the Anemone raddeana .
|
-
- HY-N0204
-
Anemoside A3
|
iGluR
|
Others
|
Pulchinenoside A is a natural triterpenoid saponin that enhances synaptic plasticity in the adult mouse hippocampus and facilitates spatial memory in adult mice.
|
-
- HY-N4263
-
-
- HY-N3557
-
Leontoside A
|
Fungal
|
Infection
|
Cauloside A (Leontoside A) is a saponin isolated from Dipsacus asper roots. Cauloside A has potent antifungal activity .
|
-
- HY-N8496
-
|
Others
|
Others
|
Clinopodiside A, a triterpenoid saponin, is isolated from Clinopodium polycephalum which is a popular Chinese traditional medicinal herb .
|
-
- HY-N9377
-
-
- HY-N2542
-
-
- HY-N7762
-
|
Others
|
Others
|
Chrysanthellin A is the main saponin-based compound from the extract of Chrysanthellum americanum. Chrysanthellin A can be used in the reserach of digestive impairments .
|
-
- HY-N0891
-
Tubeimoside-B
|
Others
|
Cancer
|
Tubeimoside II (Tubeimoside-B) is a natural analogue of oleanane type of triterpenoid saponin; show anti-inflammatory, antitumor, and antitumor-promoting effects.
|
-
- HY-N2389
-
|
Apoptosis
|
Cancer
|
Formosanin C is a diosgenin saponin isolated from Paris polyphylla and an immunomodulator with antitumor activity. Formosanin C induces apoptosis .
|
-
- HY-N1433
-
|
Bacterial
|
Infection
Inflammation/Immunology
|
Phytolaccagenin, a triterpenoid saponin, is the active component of Radix Phytolaccae. Phytolcaccagenin has antifungal activity, anti-inflammatory activity and lower toxicity
|
-
- HY-N9319
-
Decaisoside E
|
Others
|
Others
|
Fulvotomentoside A (Decaisoside E) is a triterpenoid saponin compound isolated from the flowers of Lonicera fulvotomentosa Hsu et S.C. Cheng .
|
-
- HY-N2283
-
|
ERK
Akt
Endogenous Metabolite
|
Cancer
|
Deltonin, a steroidal saponin, isolated from Dioscorea zingiberensis, has antitumor activity; Deltonin inhibits ERK1/2 and AKT activation.
|
-
- HY-N3521
-
Deapi-platycoside E
|
Others
|
Others
|
Platycoside G1, a natural product found in Platycodon grandiflorum, is a triterpenoid saponin. Platycoside G1 has potent antioxidant activities .
|
-
- HY-N2601
-
|
Others
|
Inflammation/Immunology
|
Bayogenin 3-O-β-D-glucopyranoside, a triterpenoid saponin isolated from Polygala japonica, possesses anti-inflammatory activities .
|
-
- HY-N2541
-
|
Apoptosis
Autophagy
|
Metabolic Disease
|
Gymnemic acid I is a bioactive triterpene saponin found in Gymnema sylvestre. Gymnemic acid I decreases the apoptosis under the high glucose stress .
|
-
- HY-N5064
-
|
Others
|
Neurological Disease
|
Bacoside A3, a triterpenoid saponin, is one of the major active constituents in Bacopa monnieri. Bacoside A3 has neuroprotective activity .
|
-
- HY-N9328
-
|
Others
|
Cancer
|
Tarasaponin IV, as an oleanane-type triterpene saponin, is isolated from the bark of Aralia elata. Tarasaponin IV can be used for the research of cancer .
|
-
- HY-N4246
-
|
Others
|
Neurological Disease
|
Bacopaside I, a saponin isolated from Bacopa monnieri, exbibits antioxidant properties and free radical scavenging capacity and exerts antidepressant-like effect .
|
-
- HY-N2530
-
|
Others
|
Neurological Disease
|
Notoginsenoside Fa, a protopanaxadiol (ppd)-type saponin isolated from P. notoginseng, could possibly activate and recover the function of degenerated brain .
|
-
- HY-N0556
-
|
HIV Protease
|
Infection
|
Isoescin IA is a triterpenoid saponin isolated from the seeds of Aesculus chinensis. Isoescin IA has anti-HIV-1 protease activity .
|
-
- HY-N12297
-
|
Others
|
Others
|
Ciwujianoside C2 is a saponin, that can be isolated from the leaves of Acanthopanax senticosus. Ciwujianoside C2 enhances pancreatic lipase activity in vitro .
|
-
- HY-N4215
-
|
Others
|
Inflammation/Immunology
|
11(α)-Methoxysaikosaponin F is a triterpenoid saponin isolated from Bupleurum marginatum Wall.ex DC(ZYCH) which is a promising therapeutic for liver fibrosis. 11(α)-Methoxysaikosaponin F has an IC50 of 387.7 nM with viability of hepatic stellate cells-T6 (HSCs-T6). Triterpenoid saponins have numerous targets, important network positions, and strong inhibitory activity .
|
-
- HY-N5074
-
|
Apoptosis
|
Cancer
|
Terrestrosin D, a steroidal saponin from Tribulus terrestris L., induces cell cycle arrest and cancer cells apoptosis. Terrestrosin D has antiangiogenic activities .
|
-
- HY-N7635
-
β-D-Glucopyranosyl oleanolate
|
Others
|
Others
|
Oleanolic acid 28-O-β-D-glucopyranoside (β-D-Glucopyranosyl oleanolate) is a saponin isolated from the roots of Achyranthes bidentata Blume .
|
-
- HY-N9402
-
|
Others
|
Cardiovascular Disease
|
Prosaikogenin A is a triterpene saponin isolated from Clinopodium chinense. Prosaikogenin A has significant promoting effects on platelet aggregation with an EC50 value of 12.2 μM .
|
-
- HY-N6581
-
|
Others
|
Cardiovascular Disease
Cancer
|
Notoginsenoside T5 is a dammarane 61 glycoside. Notoginsenoside T5 is isolated from the acidic deglycosylation of saponins from the roots of P. 62 notoginseng .
|
-
- HY-N0706
-
|
Apoptosis
Autophagy
|
Cancer
|
Gracillin is a steroidal saponin that can be extracted from the roots of the plant and has anti-tumor properties. Gracillin can induce cancer cell apoptosis and autophagy .
|
-
- HY-N0812
-
-
- HY-N5040
-
|
Others
|
Inflammation/Immunology
|
Ilexhainanoside D is the main triterpenoid saponin extracted from Ilex hainanensis Merr., and the combination of Ilexhainanoside D and ilexsaponin A1 has anti-inflammation effect .
|
-
- HY-N9524
-
|
Acyltransferase
|
Metabolic Disease
|
Ilexoside XLVIII is an acyl CoA cholesteryl acyl transferase (ACAT) inhibitor. Ilexoside XLVIII is a triterpene saponin isolated from an aqueous extract of the leaves of Ilex kudincha .
|
-
- HY-N0555
-
|
Others
|
Metabolic Disease
|
Escin IB is a saponin isolated from skin and the endosperm of seeds of horse chestnut (Aesculus hippocastanum). Escin IB shows inhibitory effect on pancreatic lipase activity .
|
-
- HY-N7616
-
|
Others
|
Others
|
Oleanolic acid-3-O-glucosyl(1-2)xylyl(1-3)glucosiduronic acid is a nature occurring triterpene saponin .
|
-
- HY-N12584
-
|
Others
|
Others
|
Pulchinenoside E4 (compound 2) is an oleanane-type triterpenoidal saponin that can be found in the roots ofPulsatilla chinensis . Pulchinenoside E4 shows cytotoxic activity .
|
-
- HY-N0799
-
|
Endogenous Metabolite
|
Cancer
|
Protodioscin, a major steroidal saponin in Trigonella foenum-graecum Linn., has been shown to exhibit multiple biological actions, such as anti-hyperlipidemia, anti-cancer, sexual effects and cardiovascular properties.
|
-
- HY-N6049
-
-
- HY-B2114
-
Escin
1 Publications Verification
|
Apoptosis
|
Metabolic Disease
Inflammation/Immunology
Cancer
|
Escin, a natural compound of triterpenoid saponins that can be isolated from horse chestnut (Aesculus hippocastanum) seeds, can be used as a vasoprotective anti-inflammatory, anti-edematous and anti-nociceptive agent .
|
-
- HY-N0332
-
-
- HY-N6806
-
-
- HY-N2138
-
|
Others
|
Inflammation/Immunology
|
Buddlejasaponin IVb (Compound 2), a triterpene saponin isolated from Clinopodium chinense (Benth.) O. Kuntze, Compound 2 has hemostasis efficacy, shortens thrombin time (TT) by 20.6 % .
|
-
- HY-N0048
-
|
Apoptosis
|
Cancer
|
Polyphyllin II is one of the most significant saponins in Rhizoma Paridis and has toxic effects on kinds of cancer cells. Polyphyllin II induces apoptosis through caspases activation and cell-cycle arrest .
|
-
- HY-N1422
-
|
Fungal
|
Infection
Inflammation/Immunology
|
Hecogenin is a steroid saponin isolated from Agave sisalana and is a selective inhibitor of human UDP-glucuronosyltransferases. Hecogenin has a wide spectrum of pharmacological activities, including anti-inflammatory, antifungal and gastroprotective effects .
|
-
- HY-N6850
-
|
HSP
Endogenous Metabolite
|
|
Calenduloside E (CE) is a natural pentacyclic triterpenoid saponin extracted from Aralia elata. Calenduloside E (CE) has anti-apoptotic potent by targeting heat shock protein 90 (Hsp90) .
|
-
- HY-N0330
-
|
Apoptosis
|
Cancer
|
Momordin Ic is a principal saponin constituent of Kochia scoparia L. Schrad. with anti-cancer bioactivity. Momordin Ic is also a SENP1 Inhibitor. Momordin Ic induces apoptosis through oxidative stress-regulated mitochondrial dysfunction .
|
-
- HY-N2169
-
|
Bacterial
|
Inflammation/Immunology
|
Polygalasaponin V is a triterpenoid saponin isolated from the aerial parts of Polygala japonica. Polygala japonica has been a folk medicine herb used as expectorant, anti-inflammatory, antibacterial and antidepressant agents in the south of China .
|
-
- HY-N1508
-
|
Others
|
Inflammation/Immunology
|
Ecliptasaponin A , a pentacyclic triterpenoid saponin, is one of major compounds separated from Eclipta prostrate . Eclipta prostrate is considered as a nourishing herbal medicine with pleiotropic effects, including anti-inflammatory, hepatoprotective, antioxidant, and immunomodulatory .
|
-
- HY-N1404
-
|
NF-κB
|
Inflammation/Immunology
Cancer
|
Sodium aescinate is a triterpene saponin derived from Aesculus hippocastanum seeds, with anti-inflammatory and antioxidant activities . Sodium aescinate inhibits hepatocellular carcinoma growth by targeting CARMA3/NF-κB pathway .
|
-
- HY-N0819
-
|
Apoptosis
|
Cancer
|
Raddeanin A is a natural triterpenoid saponin component of Anemone raddeana, with anti-cancer activities. Raddeanin A exerts anticancer effect on human osteosarcoma via the ROS/JNK and NF-κB signal pathway .
|
-
- HY-N0250
-
-
- HY-N0730
-
|
Autophagy
Apoptosis
|
Neurological Disease
Inflammation/Immunology
|
Diosgenin glucoside, a saponin compound extracted from Trillium tschonoskii, provides neuroprotection by regulating microglial M1 polarization. Diosgenin glucoside protects against spinal cord injury by regulating autophagy and alleviating apoptosis .
|
-
- HY-N2531
-
|
Autophagy
|
Cardiovascular Disease
|
Notoginsenoside Fc, a protopanaxadiol- (PPD-) type saponin isolated from the leaves of Panax notoginseng, effectively counteracts platelet aggregation. Notoginsenoside Fc can accelerate reendothelialization following vascular injury in diabetic rats by promoting autophagy .
|
-
- HY-N4253
-
|
Others
|
Metabolic Disease
|
Kudinoside D is a main natural component of triterpenoid saponin derived from Ilex kudingcha. Kudinoside D suppresses adipogenesis through modulation of the AMPK pathway in 3T3-L1 adipocytes .
|
-
- HY-N2190
-
-
- HY-N0705
-
|
JAK
STAT
NF-κB
|
Neurological Disease
Inflammation/Immunology
Cancer
|
Curculigoside is the main saponin in C. orchioide, exerts significant antioxidant, anti-osteoporosis, antidepressant and neuroprotection effects. Curculigoside possesses significant anti-arthritic effects in vivo and in vitro via regulation of the JAK/STAT/NF-κB signaling pathway .
|
-
- HY-N6252
-
|
Others
|
Cancer
|
Gypenoside XLVI is one of the major dammarane-type triterpenoid saponins from Gynostamma pentaphallum . Gypenoside XLVI has a tetracyclic triterpene structure and possess potent non-small cell lung carcinoma A549 cell inhibitory activity .
|
-
- HY-N3522
-
|
Others
|
Inflammation/Immunology
|
Platycoside E is a platycodigenin-type saponin isolated from the root of Platycodon grandiflorum with haemolytic activity and adjuvant potential. Platycoside E promotes the production of the sera OVA-specific IgG2a and IgG2b antibody in the ovalbumin (OVA)-immunized mice .
|
-
- HY-N7497
-
|
Others
|
Others
|
Protoescigenin is the main aglycone of horse chestnut saponin mixture known as escin. Protoescigenin is selected as substrate for exploratory chemistry towards selective protection, followed by propargyl ether formation and subsequent condensation with azido-monosaccharides, to obtain novel triazole linked conjugates of the triterpene .
|
-
- HY-N2040
-
|
Bacterial
|
Infection
Cancer
|
(20R)-Protopanaxadiol is a triterpenoid saponin metabolite of 20(R)-ginsenoside Rg3 in black ginseng. (20R)-Protopanaxadiol exhibits anti-tumor activity and cytotoxicity, and potently inhibits the growth of Helicobacter pylori .
|
-
- HY-N12141
-
|
Apoptosis
|
Inflammation/Immunology
|
Flaccidoside II inhibits proliferation and induces apoptosis in Malignant peripheral nerve sheath tumors (MPNSTs) cell lines. Flaccidoside II ameliorates collagen-induced arthritis in mice. Flaccidoside II is an active triterpenoid saponin constituent from Anemone flaccida rhizome .
|
-
- HY-N11975
-
|
Others
|
Others
|
Glycyrrhizin-6′,6′′-dimethylester (compound 23) is a licorice saponin isolated from licorice root. Glycyrrhizin-6′,6′′-dimethylester can participate as an aglycone in the generation of methyl glucuronate, producing similar threshold sweetness, licorice, and bitterness .
|
-
- HY-N2896
-
|
Reactive Oxygen Species
|
Inflammation/Immunology
|
Arjunolic acid is a saponin isolated from Cyclocarya paliurus and has various biologial activities, including antioxidant, antimicrobial, antibacterial and anti-inflammory activities. Arjunolic acid is also a potent antioxidant and plays an important role in the protection of cells and tissues against deleterious effects of reactive oxygen species .
|
-
- HY-N12017
-
|
Others
|
Infection
Cancer
|
3-O-α-L-Rhamnopyranosyl-(1→2)-α-L-arabinopyranosyl hederagenin28-O-β-D-xylopyranosyl-(1→6)-β-D-glucopyranosyl ester is a hederagenin-type saponin with antitumor and anti-inflammatory properties .
|
-
- HY-N0177
-
|
STAT
MicroRNA
|
Metabolic Disease
|
Diosgenin, a steroidal saponin, can inhibit STAT3 signaling pathway . Diosgenin is an exogenous activator of Pdia3/ERp57 . Diosgenin inhibits aortic atherosclerosis progression by suppressing macrophage miR-19b expression .
|
-
- HY-N0600
-
|
Interleukin Related
IFNAR
|
Inflammation/Immunology
|
Ginsenoside F3, a component of PPTGs (an minor saponin in the leaves of Panax ginseng), has immunoenhancing activity by regulating production and gene expression of type 1 cytokines (IL-2, IFN-gamma) and type 2 cytokines (IL-4 and IL-10) .
|
-
- HY-N7489
-
|
Parasite
|
Infection
Inflammation/Immunology
|
β-Hederin, a saponin isolated from Hedera helix L.(Araliaceae), possesses antileishmanial activity. β-Hederin exhibits IC50 values of 1.5 μM, 68 nM and 4.57 μM in L. Mexicana promastigotes, L. mexicana amastigotes and THP1 cells, respectively .
|
-
- HY-N11924
-
|
AMPK
PPAR
|
Metabolic Disease
|
Foenumoside B is a triterpene saponin isolated from Lysimachia foenum-graecum. Foenumoside B activates AMPK signaling, inhibits PPARγ-induced adipogenesis, and shifts lipid metabolism toward lipolysis. Foenumoside B can be used in the study of obesity and obesity-related metabolic diseases .
|
-
- HY-N7026
-
|
Others
|
Metabolic Disease
|
Celosin I, an oleanane-type triterpenoid saponin isolated from the seeds of Celosia argentea L, could be used as chemical markers for the quality control of C. argentea seeds. Celosin I exhibits significant hepatoprotective effect on carbon tetrachloride-induced and N,N-dimethylformamide-induced hepatotoxicity in mice .
|
-
- HY-N0554
-
|
HIV Protease
|
Infection
Cancer
|
Escin IA is a triterpene saponin isolated from Aesculus hippocastanum, which inhibits HIV-1 protease with IC50 values of 35 μM. Escin IA has anti-TNBC metastasis activity, and its action mechanisms involved inhibition of epithelial-mesenchymal transition process by down-regulating LOXL2 expression .
|
-
- HY-N9522
-
|
Others
|
Others
|
β-D-glucopyranosyl-[α-L-rhamnopyranosyl-(1→3)-βD-glucuronopyranosyl-(1→3)]-3β-hydroxyolean-12-ene28-oate, as a saponin, has a glucuronic acid attached to carbon C-3 and is isolated from S. simplex .
|
-
- HY-N0255
-
α-Hederin
|
Apoptosis
|
Others
|
alpha-Hederin (α-Hederin), a monodesmosidic triterpenoid saponin, exhibits promising antitumor potential against a variety of human cancer cell lines. alpha-Hederin could inhibit the proliferation and induce apoptosis of gastric cancer accompanied by glutathione decrement and reactive oxygen species generation via activating mitochondrial dependent pathway .
|
-
- HY-N0392
-
|
Toll-like Receptor (TLR)
PI3K
Akt
NF-κB
|
Inflammation/Immunology
|
Polygalasaponin F, an oleanane-type triterpenoid saponin extracted from Polygala japonica, decreases the release of the inflammatory cytokine tumor necrosis factor a (TNFa). Polygalasaponin F reduces neuroinflammatory cytokine secretion through the regulation of the TLR4-PI3K/AKT-NF-kB signaling pathway .
|
-
- HY-N11709
-
|
Others
|
Cancer
|
Theasaponin E1 is a tea saponin isolated from tea seeds. Theasaponin E1 exhibits potential antitumor activity against human tumor cell lines K562 and HL60. Theasaponin E1 also has quinone reductase (QR)-inducing activity and can act as an anti-tumor agent for cancer prevention .
|
-
- HY-N1654
-
|
Bacterial
|
Infection
|
2',3'-Dehydrosalannol is a potent antibacterial agent. 2',3'-Dehydrosalannol shows antibacterial activity against K. pneumonia ATCC 13883, P. aeruginosa ATCC 27853, S. aureus ATCC 25922, E. coli ATCC 11775, and E. faecalis ATCC 10541, with MIC values of 0.78, 1.56, 1.56, 6.25, and 25 µg/mL, respectively .
|
-
- HY-N12139
-
|
NO Synthase
|
Cancer
|
Nitric oxide production-IN-1(Compound 1) is a inhibitor of NO Production which isolated from Tupistra chinensis. Nitric oxide production-IN-1(Compound 1) inhibits NO production in rat abdomen macrophages induced by lipopolysaccharide
|
-
- HY-N0124
-
Dioscin
Maximum Cited Publications
8 Publications Verification
Collettiside III; CCRIS 4123
|
Autophagy
Apoptosis
|
Cancer
|
Dioscin (CCRIS 4123; Collettiside III) is a natural plant-derived steroidal saponin that has good anti-cancer activity against a variety of cancer cells. Dioscin causes DNA damage and induces apoptosis in HeLa and SiHa cells. Dioscin regulates ROS-mediated DNA damage and mitochondrial signaling pathways, exerting anticancer activity .
|
-
- HY-149436
-
|
CDK
|
Cancer
|
CDK2/Bcl2-IN-1 (compound 1), a saponin and a CDK-2 inhibitor (IC50=117.6 nM) with promising cytotoxicity against cancer cells. CDK2/Bcl2-IN-1 also inhibits Bcl-2, and induces apoptosis in A549 lung cancer cells .
|
-
- HY-N0816
-
|
Apoptosis
Pyroptosis
|
Cancer
|
Polyphyllin VI, an active saponin, possess anti-cancer activities. Polyphyllin VI induces G2/M cell cycle arrest and triggers apoptosis. Polyphyllin VI induces caspase-1-mediated pyroptosis via the induction of ROS/NF-κB/NLRP3/GSDMD signal axis in non-small cell lung cancer .
|
-
- HY-N0265
-
|
Caspase
Apoptosis
|
Cardiovascular Disease
|
Asperosaponin VI, A saponin component from Dipsacus asper, induces osteoblast differentiation through BMP‐2/p38 and ERK1/2 pathway . Asperosaponin Ⅵ inhibits apoptosis in hypoxia-induced cardiomyocyte by increasing the Bcl-2/Bax ratio and decreasing active caspase-3 expression, as well as enhancing of p-Akt and p-CREB .
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-
- HY-122920
-
|
HSV
CMV
Influenza Virus
HIV
NOD-like Receptor (NLR)
YB-1
|
Infection
Inflammation/Immunology
|
Soyasaponin II is a saponin with antiviral activity. Soyasaponin II inhibits the replication of HSV-1, HCMV, influenza virus, and HIV-1. Soyasaponin II shows potent inhibition on HSV-1 replication. Soyasaponin II serves as a inhibitor for YB-1 phosphorylation and NLRP3 inflammasome priming and could protect mice against LPS/GalN induced acute liver failure .
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- HY-N2133
-
|
Others
|
Others
|
Fallaxsaponin A (compound 5) is a natural product isolated from Polygala root .
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-
- HY-N2205
-
|
NF-κB
JNK
|
Cancer
|
Esculentoside H (EsH) is a saponin isolated from the root extract of perennial plant Phytolacca esculenta .
Esculentoside H (EH) has anti-tumor activity, the mechanism is related to the capacity for TNFrelease .
Esculentoside H (EsH) suppresses colon cancer cell migration through blockage of the JNK1/2 and NF-κB signaling-mediated matrix metalloproteinases-9 (MMP-9) expression .
|
-
- HY-101092
-
QS-21
1 Publications Verification
Stimulon
|
NOD-like Receptor (NLR)
|
Inflammation/Immunology
Cancer
|
QS-21, an immunostimulatory saponin, could be used as a potent vaccine adjuvant. QS-21 stimulates Th2 humoral and Th1 cell-mediated immune responses through action on antigen presenting cells (APCs) and T cells. QS-21 can activate the NLRP3 inflammasome with subsequent release of caspase-1 dependent cytokines, IL-1β and IL-18 .
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-
- HY-N0632
-
|
COX
NF-κB
|
Inflammation/Immunology
|
Esculentoside A (EsA), a kind of triterpene saponin isolated from roots of Phytolacca esculenta .
Esculentoside A (EsA) possesses anti-inflammatory activity in acute and chronic experimental models , has selective inhibitory activity towards cyclooxygenase-2 (COX-2) .
Esculentoside A (EsA) suppresses inflammatory responses in LPS-induced acute lung injury (ALI) through inhibition of the nuclear factor kappa B (NF-ΚB) and mitogen activated protein kinase (MAPK) signaling pathways .
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- HY-N6924
-
|
HIV
|
Infection
Metabolic Disease
|
Zingibroside R1 is dammaranae-type triterpenoid saponin, isolated from rhizomes, taproots, and lateral roots of Panax japonicas C. A. Meyer, shows excellent anti-tumor effects as well as anti-angiogenic activity .
Zingibroside R1 possesses some anti-HIV-1 activity.
Zingibroside R1 has inhibitory effects on the 2-deoxy-D-glucose (2-DG) uptake by EAT cells (IC50=91.3 μM) .
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- HY-N8198
-
|
Apoptosis
Ferroptosis
|
Cancer
|
Ardisiacrispin B displays cytotoxic effects in multi-factorial agent resistant cancer cells via ferroptotic and apoptotic cell death .
|
-
- HY-N0256
-
|
COX
NF-κB
|
Cancer
|
Hederagenin is a triterpenoid saponin with orally active and antitumor activity. Hederagenin can inhibit the expression of iNOS, COX-2, and NF-κB in cells induced by LPS stimulation. Hederagenin also increases ROS production in cancer cells, disrupts mitochondrial membrane potential, and induces apoptosis. Hederagenin also sensitizes cancer cells to Cisplatin (HY-17394) and Paclitaxel (HY-B0015), enhancing induced apoptosis. Hederagenin also has preventive potential against alcoholic liver injury .
|
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- HY-N0811
-
|
NO Synthase
COX
NF-κB
MEK
|
Inflammation/Immunology
|
Anemarsaponin B is a steroidal saponin. Anemarsaponin B decreases the protein and mRNA levels of iNOS and COX-2. Anemarsaponin B reduces the expressions and productions of pro-inflammatory cytokines, including TNF-a and IL-6. Anemarsaponin B inhibits the nuclear translocation of the p65 subunit of NF-κB by blocking the phosphorylation of IκBα. Anemarsaponin B also inhibits the phosphorylation of MAP kinase kinases 3/6 (MKK3/6) and mixed lineage kinase 3 (MLK3). Anti-inflammatory effect .
|
-
- HY-N11477
-
|
Glucosidase
|
Metabolic Disease
|
(2α,3β,4α)-2,3,19-Trihydroxyurs-12-ene-23,28-dioic acid is a saponin that can be isolated from Rubus ellipticus var. obcordatus. (2α,3β,4α)-2,3,19-Trihydroxyurs-12-ene-23,28-dioic acid inhibits α-Glucosidase with an IC50 of 1.68 mM .
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-
- HY-N12138
-
|
Glucosidase
|
Metabolic Disease
|
Flaccidoside III is a flavonoid and triterpenoid isolated from the aerial parts of N. sativa (Ranunculaceae). Flaccidoside III inhibits α-Glucosidase (IC50: 256.7 μM) and has potential antioxidant and antidiabetic activities .
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-
- HY-N9521
-
|
Others
|
Cancer
|
3-O-β-D-Glucopyranosyl(1→2)-[a-Lrhamnopyranosyl(1→3)]-β-D-glucopyranosyl 28-O-β-D-glucuronopyranoside, a saponin, is isolated from Polaskia chichipe Backbg. 3-O-β-D-Glucopyranosyl(1→2)-[a-Lrhamnopyranosyl(1→3)]-β-D-glucopyranosyl 28-O-β-D-glucuronopyranoside shows ability to inhibit melanin biosynthesis by B16 melanoma cell with inhibitory activity 84.2% at 100μM[1].
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Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
- HY-N11983
-
-
- HY-N12272
-
-
- HY-N11068
-
-
- HY-N12190
-
-
- HY-N8096
-
-
- HY-N5135
-
-
- HY-N8098
-
-
- HY-N7614
-
-
- HY-N8610
-
-
- HY-N8763
-
-
- HY-W019829
-
-
- HY-N8609
-
-
- HY-N3323
-
-
- HY-N11433
-
-
- HY-16942
-
-
- HY-N0797
-
-
- HY-N9324
-
-
- HY-N8804
-
-
- HY-N6058
-
-
- HY-N12016
-
-
- HY-N1411
-
-
- HY-N6256
-
-
- HY-N7273
-
-
- HY-N12225
-
-
- HY-N7687
-
-
- HY-N12137
-
-
- HY-N2109
-
-
- HY-125570
-
-
- HY-N12128
-
-
- HY-N8211
-
-
- HY-N12002
-
-
- HY-N0615
-
-
- HY-N0863
-
-
- HY-N0864
-
-
- HY-107309
-
-
- HY-N0345
-
-
- HY-N8216
-
-
- HY-N12290
-
-
- HY-N4271
-
-
- HY-N7966
-
-
- HY-N8222
-
-
- HY-N9373
-
-
- HY-N4270
-
-
- HY-N0302
-
-
- HY-107284
-
-
- HY-N6265
-
-
- HY-N5087
-
-
- HY-N9989
-
-
- HY-N7235
-
-
- HY-N0206
-
-
- HY-N0266
-
-
- HY-N6982
-
-
- HY-N2606
-
-
- HY-107314
-
-
- HY-N5071
-
-
- HY-N12383
-
-
- HY-N0910
-
-
- HY-N4135
-
-
- HY-107300
-
-
- HY-N6079
-
-
- HY-N1479
-
-
- HY-N3520
-
-
- HY-N1932
-
-
- HY-N2001
-
-
- HY-N6970
-
-
- HY-N7919
-
-
- HY-N2002
-
-
- HY-N12293
-
-
- HY-N12578
-
-
- HY-N4087
-
-
- HY-N0588
-
-
- HY-133237
-
-
- HY-N12294
-
-
- HY-N12296
-
-
- HY-N12424
-
-
- HY-N3519
-
-
- HY-N6088
-
-
- HY-125702
-
-
- HY-N11452
-
-
- HY-N11458
-
-
- HY-125121
-
-
- HY-N11115
-
-
- HY-N0818
-
-
- HY-N0254
-
-
- HY-N5078
-
-
- HY-107311
-
-
- HY-N0204
-
-
- HY-N4263
-
-
- HY-N3557
-
-
- HY-N8496
-
-
- HY-N9377
-
-
- HY-N2542
-
-
- HY-N7762
-
-
- HY-N0891
-
-
- HY-N2389
-
-
- HY-N1433
-
-
- HY-N9319
-
-
- HY-N2283
-
-
- HY-N3521
-
-
- HY-N2601
-
-
- HY-N2541
-
-
- HY-N5064
-
-
- HY-N9328
-
-
- HY-N4246
-
-
- HY-N2530
-
-
- HY-N0556
-
-
- HY-N12297
-
-
- HY-N4215
-
-
- HY-N5074
-
-
- HY-N7635
-
-
- HY-N9402
-
-
- HY-N6581
-
-
- HY-N0706
-
-
- HY-N0812
-
-
- HY-N5040
-
-
- HY-N9524
-
-
- HY-N0555
-
-
- HY-N7616
-
-
- HY-N12584
-
-
- HY-N0799
-
-
- HY-N6049
-
-
- HY-B2114
-
-
- HY-N0332
-
-
- HY-N6806
-
-
- HY-N2138
-
-
- HY-N0048
-
-
- HY-N1422
-
-
- HY-N6850
-
-
- HY-N0330
-
-
- HY-N2169
-
-
- HY-N1508
-
-
- HY-N1404
-
-
- HY-N0819
-
-
- HY-N0250
-
-
- HY-N0730
-
-
- HY-N2531
-
-
- HY-N4253
-
-
- HY-N2190
-
-
- HY-N0705
-
-
- HY-N6252
-
-
- HY-N3522
-
-
- HY-N7497
-
-
- HY-N2040
-
-
- HY-N12141
-
-
- HY-N11975
-
-
- HY-N2896
-
-
- HY-N12017
-
-
- HY-N0177
-
-
- HY-N0600
-
-
- HY-N7489
-
-
- HY-N11924
-
-
- HY-N7026
-
-
- HY-N0554
-
-
- HY-N9522
-
-
- HY-N0255
-
-
- HY-N0392
-
-
- HY-N11709
-
-
- HY-N1654
-
|
Infection
Natural Products
Classification of Application Fields
Source classification
Plants
Azadirachta indica A. Juss.
Disease Research Fields
Meliaceae
|
Bacterial
|
2',3'-Dehydrosalannol is a potent antibacterial agent. 2',3'-Dehydrosalannol shows antibacterial activity against K. pneumonia ATCC 13883, P. aeruginosa ATCC 27853, S. aureus ATCC 25922, E. coli ATCC 11775, and E. faecalis ATCC 10541, with MIC values of 0.78, 1.56, 1.56, 6.25, and 25 µg/mL, respectively .
|
-
- HY-N12139
-
-
- HY-N0124
-
-
- HY-149436
-
-
- HY-N0816
-
-
- HY-N0265
-
-
- HY-122920
-
-
- HY-N2133
-
-
- HY-N2205
-
-
- HY-101092
-
-
- HY-N0632
-
-
- HY-N6924
-
-
- HY-N8198
-
-
- HY-N0256
-
-
- HY-N0811
-
-
- HY-N11477
-
|
Triterpenes
Structural Classification
Terpenoids
Source classification
Rosaceae
Plants
Rubus ellipticus Smith
|
Glucosidase
|
(2α,3β,4α)-2,3,19-Trihydroxyurs-12-ene-23,28-dioic acid is a saponin that can be isolated from Rubus ellipticus var. obcordatus. (2α,3β,4α)-2,3,19-Trihydroxyurs-12-ene-23,28-dioic acid inhibits α-Glucosidase with an IC50 of 1.68 mM .
|
-
- HY-N12138
-
-
- HY-N9521
-
-
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Inquiry Information
- Product Name:
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