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Results for "

TFEB

" in MedChemExpress (MCE) Product Catalog:

7

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Natural
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1

Recombinant Proteins

1

Antibodies

Cat. No. Compare Product Name Species Source
  • HY-P701228
    TFEB protein, Human (N-His)

    ALPHATFEB; BHLHE35; TCFEB

    		 Human E. coli
    TFEB Protein, a transcription factor, masterfully regulates lysosomal functions, autophagy, lipid catabolism, energy metabolism, and immune responses. Recognizing E-box and CLEAR-box sequences, it controls gene expression in response to nutrient availability. MTOR phosphorylation inhibits TFEB, retaining it cytosolic, while starvation induces dephosphorylation, leading to nuclear localization and gene activation. TFEB promotes autophagy and plays a role in immune responses, including antibacterial defense. The drug eltrombopag inhibits TFEB by binding to its bHLH domain, disrupting DNA-binding. TFEB protein, Human (N-His) is the recombinant human-derived TFEB protein, expressed by E. coli , with N-His labeled tag. The total length of TFEB protein, Human (N-His) is 476 a.a., with molecular weight of ~57.0 kDa.

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