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Results for "

ecdysteroid

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Autophagy (1) Caspase (1) Drug Metabolite (1) Endogenous Metabolite (1) Insulin Receptor (1)
By Research Areas:	Cardiovascular Disease (2) Endocrinology (1) Inflammation/Immunology (2) Metabolic Disease (2)

Inhibitors & Agonists

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N2548

Turkesterone

Others Cardiovascular Disease

Turkesterone is a potent ecdysteroid. Turkesterone acts as an ecdysteroid receptor (EcR) agonist in some insect systems .
HY-128030

Makisterone A

Others Endocrinology

Makisterone A, a 28-carbon moulting hormone, has been identified as the major free pupal ecdysteroid in the honey bee, Apis mellifera .

Turkesterone	Others	Cardiovascular Disease
Turkesterone is a potent ecdysteroid. Turkesterone acts as an ecdysteroid receptor (EcR) agonist in some insect systems .

Makisterone A	Others	Endocrinology
Makisterone A, a 28-carbon moulting hormone, has been identified as the major free pupal ecdysteroid in the honey bee, Apis mellifera .

HY-113890

Halofenozide RH-0345	Others	Others
Halofenozide (RH-0345) is an *ecdysteroid* agonist. RH-0345 belongs to a new group of insect growth regulators (IGRs) with a benzoylhydrazine structure that mimic the action of the natural insect molting hormone 20-hydroxyecdysone .

HY-N6979

Crustecdysone 2 Publications Verification 20-Hydroxyecdysone	Caspase Autophagy Endogenous Metabolite	Cardiovascular Disease
Crustecdysone (20-Hydroxyecdysone) is a naturally occurring ecdysteroid hormone isolated from Serratula coronata which controls the ecdysis (moulting) and metamorphosis of arthropods, it inhibits caspase activity and induces autophagy via the 20E nuclear receptor complex, EcR-USP . Crustecdysone exhibits regulatory or protective roles in the cardiovascular system . Crustecdysone is an active metabolite of Ecdysone (HY-N0179) .

HY-N12156

Ajugasterone C 2-acetate

Others Others

Ajugasterone C 2-acetate is an ecdysteroid that can be isolated from Cyanotis arachnoidea .
HY-N10382

20,26-Dihydroxyecdysone

Drug Metabolite Others

20,26-Dihydroxyecdysone is a predominant ecdysteroid metabolite .
HY-103273

Muristerone A

Others Others

Muristerone A is a phytoecdysteroid analog of ecdysone and a potent agonist of ecdysteroid receptor with a K_d of 1 nM .
HY-N10747

Polyporoid B

Others Inflammation/Immunology

Polyporoid B is a ergostane-type ecdysteroid that exhibits potent anti-inflammatory activity in vivo .
HY-N10746

Polyporoid C

Others Inflammation/Immunology

Polyporoid C is a ergostane-type ecdysteroid that exhibits potent anti-inflammatory activity in vivo .
HY-N3792

20-Hydroxyecdysone 2,3:20,22-diacetonide

Others Metabolic Disease

20-Hydroxyecdysone 2,3:20,22-diacetonide is a natural ecdysteroid .

Ajugasterone C 2-acetate	Others	Others
Ajugasterone C 2-acetate is an ecdysteroid that can be isolated from Cyanotis arachnoidea .

20,26-Dihydroxyecdysone	Drug Metabolite	Others
20,26-Dihydroxyecdysone is a predominant ecdysteroid metabolite .

Muristerone A	Others	Others
Muristerone A is a phytoecdysteroid analog of ecdysone and a potent agonist of ecdysteroid receptor with a K_d of 1 nM .

Polyporoid B	Others	Inflammation/Immunology
Polyporoid B is a ergostane-type ecdysteroid that exhibits potent anti-inflammatory activity in vivo .

Polyporoid C	Others	Inflammation/Immunology
Polyporoid C is a ergostane-type ecdysteroid that exhibits potent anti-inflammatory activity in vivo .

20-Hydroxyecdysone 2,3:20,22-diacetonide	Others	Metabolic Disease
20-Hydroxyecdysone 2,3:20,22-diacetonide is a natural ecdysteroid .

HY-N1534

Ponasterone A 25-Deoxyecdysterone
Ponasterone A (25-Deoxyecdysterone), an ecdysteroid, has strong affinity for the ecdysone receptor. Ponasterone A is a potent regulator of gene expression in cells and transgenic animals, enabling reporter genes to be turned on and off rapidly .

HY-118541

RH-5849	Others	Others
RH-5849 is an orally active agonist for non-steroidal ecdysteroid, which inhibits the larval growth of Plodia inferpuncteila in a dose-dependent manner. RH-5849 exhibits molting hormone activity .

HY-N2196

Ajugasterone C
Ajugasterone C is an ecdysteroid isolated from Leuzea carthamoides. Ajugasterone C shows significant inhibitory effect at 100 mg/kg dose on rat paw oedema development due to Carrageenan-induced inflammation in Sprague Dawley rats .

HY-124097

HNMPA-(AM)3	Insulin Receptor	Metabolic Disease
HNMPA-(AM)3 is a cell-permeable and selective insulin receptor tyrosine kinase inhibitor analog of HNMPA. HNMPA-(AM)3 greatly inhibits the ability of prothoracicotropic hormone (PTTH) to activate ERK phosphorylation and stimulate ecdysteroidogenesis. HNMPA-(AM)3 is also effective in inhibiting ecdysteroid production (IC₅₀=14.2 μM) and insulin receptor activity (IC₅₀ is 14.2 μM and 200 μM in mosquitoes and mammals, respectively) .

Turkesterone	Cardiovascular Disease other families Classification of Application Fields Source classification Plants Disease Research Fields Steroids	Others
Turkesterone is a potent ecdysteroid. Turkesterone acts as an ecdysteroid receptor (EcR) agonist in some insect systems .

Makisterone A	Classification of Application Fields Source classification Chenopodium quinoa Willd. Plants Disease Research Fields Endocrinology Steroids Chenopodiaceae	Others
Makisterone A, a 28-carbon moulting hormone, has been identified as the major free pupal ecdysteroid in the honey bee, Apis mellifera .

Crustecdysone 2 Publications Verification 20-Hydroxyecdysone	Cardiovascular Disease Structural Classification other families Classification of Application Fields Animals Source classification Plants Compositae Endogenous metabolite Disease Research Fields Canavalia gladiata (Jacq.) DC. Steroids	Caspase Autophagy Endogenous Metabolite
Crustecdysone (20-Hydroxyecdysone) is a naturally occurring ecdysteroid hormone isolated from Serratula coronata which controls the ecdysis (moulting) and metamorphosis of arthropods, it inhibits caspase activity and induces autophagy via the 20E nuclear receptor complex, EcR-USP . Crustecdysone exhibits regulatory or protective roles in the cardiovascular system . Crustecdysone is an active metabolite of Ecdysone (HY-N0179) .

Muristerone A	Ipomoea nil (Linnaeus) Roth Classification of Application Fields Source classification Other Diseases Plants Disease Research Fields Convolvulaceae Steroids	Others
Muristerone A is a phytoecdysteroid analog of ecdysone and a potent agonist of ecdysteroid receptor with a K_d of 1 nM .

Ajugasterone C 2-acetate	Structural Classification Natural Products Commelinaceae Source classification Cyanotis arachnoidea C. B. Clarke Plants	Others
Ajugasterone C 2-acetate is an ecdysteroid that can be isolated from Cyanotis arachnoidea .

20-Hydroxyecdysone 2,3:20,22-diacetonide	Triterpenes Structural Classification Terpenoids Source classification Amphimas pterocarpoides Harms Plants Compositae	Others
20-Hydroxyecdysone 2,3:20,22-diacetonide is a natural ecdysteroid .

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ecdysteroid

Inhibitors & Agonists

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Natural
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