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Results for "

flavonolignan

" in MedChemExpress (MCE) Product Catalog:

9

Inhibitors & Agonists

9

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N0779A
    Silybin
    2 Publications Verification

    Silibinin

    		 Apoptosis Inflammation/Immunology Cancer
    Silybin is a flavonolignan isolated from milk thistle (Silybum marianum) seeds. Silybin induces apoptosis and exhibits hepatoprotective, antioxidant, anti-inflammatory, anti-cancer activity .
    Silybin
  • HY-N10986
    (±)-Hydnocarpin

    		Bacterial Infection Inflammation/Immunology
    (±)-Hydnocarpin is a flavonolignan. (±)-Hydnocarpin can inhibit the growth of S. aureus with a MIC50 value of 3.1 μM .
    (±)-Hydnocarpin
  • HY-129584
    Lepidiline B

    		Others Inflammation/Immunology
    Lepidiline B is a flavonolignan isolated from the roots of Brassicaceae Lepidium meyenii. Lepidiline B exhibits anti-inflammation activities in human cancer cell lines .
    Lepidiline B
  • HY-N12360A
    2,3-Dehydrosilybin B

    		Others Others
    2,3-Dehydrosilybin B is an enantiomer formed by the oxidation of the natural flavonolignans silybin A .
    2,3-Dehydrosilybin B
  • HY-N8180
    Silyamandin

    		Others Others
    Silyamandin is a flavonolignan compound. Silydianin can form Silyamandin through oxidative degradation .
    Silyamandin
  • HY-N0647
    Silychristin

    		Monocarboxylate Transporter Endocrinology
    Silychristin is an abundant flavonolignan present in the fruits of Silybum marianum, with antioxidant properties. Silychristin is a potent inhibitor of the thyroid hormone transporter MCT8, and elicits a strong inhibition of T3 uptake with an IC50 of 110 nM .
    Silychristin
  • HY-N7046
    Silybin B

    Silibinin B

    		 Amyloid-β Neurological Disease Cancer
    Silybin B, a flavonolignan separated from Silybum marianum, has anti-tumor activity. Silybin B is the most potent antifibrillogenic and anti-oligomeric component of silymarin and proposes it as a promising anti Alzheimer’s disease agent candidate .
    Silybin B
  • HY-N7045
    Isosilybin B
    1 Publications Verification

    		 Androgen Receptor Apoptosis Cancer
    Isosilybin B, a flavonolignan isolated from Silybum marianum, has anti-prostate cancer (PCA) activity via inhibiting proliferation and inducing G1 phase arrest and apoptosis. Isosilybin B causes androgen receptor (AR) degradation .
    Isosilybin B
  • HY-N7043
    Isosilybin A
    1 Publications Verification

    		 Apoptosis Cancer
    Isosilybin A, a flavonolignan isolated from silymarin, has anti-prostate cancer (PCA) activity. Isosilybin A inhibits proliferation and induces G1 phase arrest and apoptosis in cancer cells, which activates apoptotic machinery in PCA cells via targeting Akt-NF-κB-androgen receptor (AR) axis .
    Isosilybin A

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