Search Result
Results for "
tobacco
" in MedChemExpress (MCE) Product Catalog:
2
Biochemical Assay Reagents
7
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-W015806
-
|
Endogenous Metabolite
|
Others
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3-Pyridineacetic acid is a higher homologue of nicotinic acid, a breakdown product of nicotine (and other tobacco alkaloids) .
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- HY-W004515
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Endogenous Metabolite
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Others
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3-Pyridineacetic acid hydrochloride is a higher homologue of nicotinic acid, a breakdown product of nicotine (and other tobacco alkaloids) .
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- HY-121999
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(Z)-Abienol
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Bacterial
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Infection
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(+)-cis-Abienol (Compound Z-abienol), a diterpenoid, can be isolated from leaves of tobacco. (+)-cis-Abienol inhibits hyphal growth of P. nicotianae .
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- HY-152259
-
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TMV
|
Infection
|
TMV-IN-4 (compound 3) is a tobacco mosaic virus (TMV) inhibitor that effectively induces resistance and enhances plant tolerance to TMV infection by interacting with TMV helicase. TMV-IN-4 enhances peroxidase and superoxide dismutase activity, thereby increasing resistance to TMV in tobacco .
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- HY-N8024
-
|
TMV
|
Infection
|
Rubinaphthin A is a naphthohydroquinone that can be found in the roots of Rubia yunnanensis. Rubinaphthin A exhibits inhibitory activity against tobacco mosaic virus (TMV) .
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-
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- HY-W001909
-
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nAChR
|
Metabolic Disease
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Myosmine, a specific tobacco alkaloid in nuts and nut products, has low affinity for a4b2 nicotinic acetylcholinergic receptors (nAChR) with a Ki of 3300 nM .
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-
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- HY-126047
-
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Others
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Others
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(S)-(-)-Anatabine is a Ti plasmid mutant.
(S)-(-)-Anatabine has the activity of inducing tobacco blastoma to transform
into nicotinic alkaloids. (S)-(-)-Anatabine can be used in the study of
biotransformation of cotyl teratoma .
|
-
-
- HY-155044
-
|
TMV
Fungal
|
Infection
|
TMV-IN-5 (compound 1a) is an anti-plant virus/fungal agent. TMV-IN-5 inhibits viral assembly by binding to tobacco mosaic virus (TMV) CP. TMV-IN-5 can be used in the development of pesticides .
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-
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- HY-W041301
-
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Others
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Others
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(±)-Dihydroactinidiolide, an important aroma compound of black tea and tobacco, has been isolated from several plants. (±)-Dihydroactinidiolide can be formation from β-Carotene by the treatment of polyphenoloxidase, the lipoxygenase, and the xanthine oxidase .
|
-
-
- HY-N12249
-
|
Amyloid-β
TMV
|
Infection
Neurological Disease
Inflammation/Immunology
|
7-Deoxy-trans-dihydronarciclasine, an alkaloid, is a tobacco mosaic virus (TMV) inhibitor (IC50: 1.80 μM). 7-Deoxy-trans-dihydronarciclasine is an anti-neuroinflammatory agent. 7-Deoxy-trans-dihydronarciclasine decreases the Aβ and APP levels in the cerebral cortex of Tg2576 mice .
|
-
-
- HY-119458
-
|
Topoisomerase
TMV
Fungal
|
Infection
|
Luotonin A is an antiviral and antiphytopathogenic fungus agent. Luotonin A has good antiviral activity against tobacco mosaic virus (TMV). Luotonin A also has certain inhibitory activity on topoisomerase I and topoisomerase II. Luotonin A shows antitumor activity .
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-
- HY-145324
-
|
TMV
|
Infection
|
Antiviral agent 14 is an antiviral agent against the tobacco mosaic virus (TMV) and cucumber mosaic virus (CMV). The EC50 values of Antiviral agent 14 against TMV and CMV with EC50 values of 135.5 μg/mL and 178.6 μg/mL, respectively .
|
-
-
- HY-148568
-
|
TMV
Bacterial
|
Infection
Inflammation/Immunology
Cancer
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TMV-IN-2, chalcone derivative, is a tobacco mosaic virus (TMV) inhibitor. TMV-IN-2 has antiviral activity against TMV with an EC50 value of 89.9 μg/mL. TMV-IN-2 can be used for the research of infection, inflammation and tumor .
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-
- HY-148569
-
|
TMV
Bacterial
|
Infection
Inflammation/Immunology
Cancer
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TMV-IN-3, chalcone derivative, is a tobacco mosaic virus (TMV) inhibitor. TMV-IN-3 has antiviral activity against TMV with an EC50 value of 120.3 μg/mL. TMV-IN-3 can be used for the research of infection, inflammation and tumor .
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-
- HY-N8521
-
|
TMV
Parasite
|
Infection
|
6-O-Methacrylate, a trilobolide, is isolated from the leaves of Wedelia trilobata. 6-O-Methacrylate displays marked antimalarial activity, with IC50 of 8.9 μg/mL against P. falciparum parasite. 6-O-Methacrylate also has anti-tobacco mosaic virus (TMV) activity .
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-
- HY-148567
-
|
TMV
Bacterial
|
Infection
Inflammation/Immunology
Cancer
|
TMV-IN-1, chalcone derivative, is a tobacco mosaic virus (TMV) inhibitor. TMV-IN-1 has good therapeutic activity and protective activity against TMV with EC50 values of 70.7 μg/mL and 60.8 μg/mL, respectively. TMV-IN-1 can be used for the research of infection, inflammation and tumor .
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-
- HY-B1178
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(-)-Cotinine; (S)-Cotinine; NIH-10498
|
Endogenous Metabolite
|
Cancer
|
Cotinine ((-)-Cotinine), an alkaloid in tobacco and a major metabolite of nicotine, is used as a biological indicator to measure the composition of tobacco smoke
|
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- HY-126047A
-
|
Others
|
Inflammation/Immunology
|
(R,S)-Anatabine is a a minor tobacco alkaloid found in the Solanaceae family of plants that can be used as a specific marker for the detection of tobacco use .
|
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- HY-156533A
-
|
5-HT Receptor
|
Neurological Disease
Inflammation/Immunology
Cancer
|
5-HT2 agonist-1 (Compound 24) free base is a 5-HT2A & 5-HT2B & 5-HT2C agonist, with IC50s of 10 nM, 8.3, and 1.6 nM respectively. 5-HT2 agonist-1 free base can be used for research of depression, alcoholism, tobacco and cocaine addiction, inflammation, cluster headache, PTSD, seizure disorders and other CNS disorders .
|
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- HY-156533
-
|
5-HT Receptor
|
Cancer
|
5-HT2 agonist-1 (Compound 24) is a 5-HT2A & 5-HT2B & 5-HT2C agonist, with IC50s of 10 nM, 8.3, and 1.6 nM respectively. 5-HT2 agonist-1 free base can be used for research of depression, alcoholism, tobacco and cocaine addiction, inflammation, cluster headache, PTSD, seizure disorders and other CNS disorders .
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- HY-Y0189S
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Wintergreen oil-d4
|
COX
|
Inflammation/Immunology
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Methyl Salicylate-d4 is the deuterium labeled Methyl Salicylate[1]. Methyl Salicylate (Wintergreen oil) is a topical analgesic and anti-inflammatory agent. Also used as a pesticide, a denaturant, a fragrance ingredient, and a flavoring agent in food and tobacco products[2]. A systemic acquired resistance (SAR) signal in tobacco[3]. A topical nonsteroidal anti-inflammatory agent (NSAID). Methyl salicylate lactoside is a COX inhibitor[5].
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- HY-156534
-
|
5-HT Receptor
|
Neurological Disease
Inflammation/Immunology
Cancer
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5-HT2A&5-HT2C agonist-1 (Example 2) is a 5-HT2A & 5-HT2C agonist, with IC50s of 196 nM and 0.9 nM respectively. 5-HT2A&5-HT2C agonist-1 can be used for research of depression, alcoholism, tobacco and cocaine addiction, inflammation, cluster headache, PTSD, seizure disorders and other CNS disorders .
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- HY-126047AR
-
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Others
|
Inflammation/Immunology
|
(R,S)-Anatabine (Standard) is the analytical standard of (R,S)-Anatabine. This product is intended for research and analytical applications. (R,S)-Anatabine is a a minor tobacco alkaloid found in the Solanaceae family of plants that can be used as a specific marker for the detection of tobacco use .
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- HY-N6085
-
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Others
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Others
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N-Caffeoylputrescine,(E)- is a caffeic acid amide found in the tobacco plants (Nicotiana tabacum L.) .
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-
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- HY-N10110
-
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TMV
|
Infection
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(±)-Phrymarolin II is a promising new class of plant virus (tobacco mosaic virus) inhibitors.
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-
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- HY-Y0189
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Salicylic acid methyl ester
|
COX
|
Inflammation/Immunology
|
Methyl Salicylate (Wintergreen oil) is a topical analgesic and anti-inflammatory agent. Also used as a pesticide, a denaturant, a fragrance ingredient, and a flavoring agent in food and tobacco products . A systemic acquired resistance (SAR) signal in tobacco . A topical nonsteroidal anti-inflammatory agent (NSAID). Methyl salicylate lactoside is a COX inhibitor .
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- HY-N7532
-
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TMV
|
Infection
|
Yadanzioside I is a potent anti-tobacco mosaic virus (TMV) quassinoid with an IC50 of 4.22 μM .
|
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- HY-N7194
-
|
TMV
|
Infection
|
Yadanzioside L is a quassinoid and shows anti-tobacco mosaic virus (TMV) activity (IC50=4.86 μM) .
|
-
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- HY-W127341
-
|
Biochemical Assay Reagents
|
Others
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Phytanic acid methyl esteris an esterified form of long-chain fatty acid methyl esters and phytanic acid, which has been found in Greek tobacco.
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-
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- HY-W040194
-
|
Others
|
Others
|
Clomazone is a broad spectrum herbicide used for control of annual grasses and broadleaf weeds in cotton, peas, pumpkins, soybeans, sweet potatoes, and tobacco .
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- HY-Y0507
-
|
|
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DL-Serine, a fundamental metabolite, is a mixture of D-Serine and L-Serine. DL-Serine has antiviral activity against the multiplication of tobacco mosaic virus (TMV) .
|
-
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- HY-N1836
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3-Hydroxy-3-acetonyloxindole
|
|
|
3-Acetonyl-3-hydroxyoxindole (AHO) is a potent systemic acquired resistance (SAR) inducer in plants. 3-Acetonyl-3-hydroxyoxindole induces resistance in tobacco plants against infection with tobacco mosaic virus (TMV) and the fungal pathogen Erysiphe cichoracearum. 3-Acetonyl-3-hydroxyoxindole increases the level of pathogenesis-related gene 1 (PR-1) expression, salicylic acid (SA) accumulation and phenylalanine ammonia-lyase activity .
|
-
-
- HY-103673
-
|
Adenosine Deaminase
|
Neurological Disease
|
AMPD2 inhibitor 1 is an adenosine monophosphate deaminase 2 (AMPD2) inhibitor, used in the research of sugar craving, salt craving, umami craving, and addictions including agent, tobacco, nicotine and alcohol addictions.
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-
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- HY-163201
-
|
TMV
|
Infection
|
TMV-IN-7 (compound G2) is a potent inhibitor of tobacco mosaic virus (TMV). TMV-IN-7 exhibits strong hydrophobic interactions to obstructing the virus’s self-assembly .
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- HY-N4210
-
|
TMV
|
Infection
Cancer
|
Yadanziolide A, isolated from the cultivated dry seeds of Brucea javanica, has strong antiviral activities with IC50 of 5.5 μM against tobacco mosaic virus. Yadanziolide A shows significant antitumor effects .
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- HY-W001909S
-
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nAChR
|
Metabolic Disease
|
Myosmine-d4 is the deuterium labeled Myosmine. Myosmine, a specific tobacco alkaloid in nuts and nut products, has low affinity for a4b2 nicotinic acetylcholinergic receptors (nAChR) with a Ki of 3300 nM[1][2].
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- HY-W004515S
-
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Endogenous Metabolite
|
Others
|
3-Pyridylacetic acid-d4 (hydrochloride) is the deuterium labeled 3-Pyridylacetic acid hydrochloride[1]. 3-Pyridineacetic acid hydrochloride is a higher homologue of nicotinic acid, a breakdown product of nicotine (and other tobacco alkaloids)[2][3].
|
-
-
- HY-W017463
-
|
TMV
|
Infection
|
trans-3-(3-Pyridyl)acrylic acid (compound 15) is a trans-3-aryl acrylic acid. trans-3-(3-Pyridyl)acrylic acid shows antiviral activity against tobacco mosaic virus (TMV) .
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- HY-W718796
-
|
Isotope-Labeled Compounds
TMV
|
Cancer
|
DL-Serine- 15N is 15N-labeled DL-Serine (HY-Y0507) DL-Serine, a fundamental metabolite, is a mixture of D-Serine and L-Serine. DL-Serine has antiviral activity against the multiplication of tobacco mosaic virus (TMV).
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-
-
- HY-Y0507S
-
|
TMV
Isotope-Labeled Compounds
|
Infection
Cancer
|
DL-Serine-2,3,3-d3 is the deuterium labeled DL-Serine. DL-Serine, a fundamental metabolite, is a mixture of D-Serine and L-Serine. DL-Serine has antiviral activity against the multiplication of tobacco mosaic virus (TMV)[1].
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-
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- HY-B1532
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(S)-Anabasine; (+)-Anabasine
|
nAChR
|
Neurological Disease
|
Anabasine ((S)-Anabasine) is an alkaloid that found as a minor component in tobacco (Nicotiana). Anabasine is a botanical pesticide nicotine, acts as a full agonist of nicotinic acetylcholine receptors (nAChRs). Anabasine induces depolarization of TE671 cells endogenously expressing human fetal muscle-type nAChRs (EC50=0.7 µM) .
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-
-
- HY-W014928
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(S)-Anabasine hydrochloride; (+)-Anabasine hydrochloride
|
nAChR
|
Neurological Disease
|
Anabasine ((S)-Anabasine) hydrochloride is an alkaloid that found as a minor component in tobacco (Nicotiana). Anabasine is a botanical pesticide nicotine, acts as a full agonist of nicotinic acetylcholine receptors (nAChRs). Anabasine induces depolarization of TE671 cells endogenously expressing human fetal muscle-type nAChRs (EC50=0.7 µM) .
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-
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- HY-162400
-
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Others
|
Infection
|
TMV-IN-8 (compound 7 d) is an anti tobacco mosaic virus (TMV) agent with an antiviral EC50of 157.6 μg/mL.TMV-IN-8blocks the assembly of TMV by binding with coat protein (Kd = 0.7 μM) and suppressed TMV coat protein gene expression and biosynthesis process .
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-
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- HY-N7434
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Diethylnitrosamine; DEN
|
DNA/RNA Synthesis
|
Cancer
|
N-Nitrosodiethylamine (Diethylnitrosamine) is a potent hepatocarcinogenic dialkylnitrosoamine. N-Nitrosodiethylamine is mainly present in tobacco smoke, water, cheddar cheese, cured, fried meals and many alcoholic beverages. N-Nitrosodiethylamine is responsible for the changes in the nuclear enzymes associated with DNA repair/replication. N-Nitrosodiethylamine results in various tumors in all animal species. The main target organs are the nasal cavity, trachea, lung, esophagus and liver.
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-
-
- HY-119698
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SD 8339; N-Benzyl-9-(tetrahydro-2h-pyran-2-yl)adenine
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Others
|
Others
|
BAP9THP is a synthetic cytokinin derivative and a growth regulator. BAP9THP promotes chlorophyll retention (and senescence delay) in plant tissues exceptionally strongly, and growth of tobacco callus almost as strongly as 6-Benzylaminopurine (BAP). BAP9THP induces adventitious shoot formation ignificantly more strongly than N6-isopentenyladenine or Kinetin .
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-
-
- HY-135560
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Nicotellin
|
Cytochrome P450
|
Neurological Disease
|
Nicotelline (Nicotellin) is a nicotine-related alkaloid, as well as a weak inhibitor of human cDNA-expressed cytochrome P-450 2A6 (CYP2A6). CYP2A6 mediates coumarin 7-hydroxylation, while Nicotelline fails to exhibit inhibition at 300 μM. Nicotelline can be used as a tracer and biomarker of particulate matter (PM) derived from tobacco smoke .
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-
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- HY-19918A
-
|
NF-κB
Amyloid-β
nAChR
|
Neurological Disease
Inflammation/Immunology
|
Anatabine dicitrate is a tobacco alkaloid that can cross the blood-brain barrier. Anatabine dicitrate is a potent α4β2 nAChR agonist. Anatabine dicitrate inhibits NF-κB activation lower amyloid-β (Aβ) production by preventing the β-cleavage of amyloid precursor protein (APP). Anatabine dicitrate has anti-inflammatory effects and has the potential for neurodegenerative disorders treatment .
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-
-
- HY-162376
-
|
Bacterial
|
Infection
|
T3SS-IN-4 (Compound Z-8) is a T3SS inhibitor that can inhibit the expression of Xanthomonas oryzae pv oryzae (Xoo) T3SS-related genes without affecting bacterial growth. T3SS-IN-4 can effectively reduce the hypersensitive response (HR) induced by Xoo in tobacco and lower the pathogenicity of Xoo in rice .
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-
-
- HY-P2717
-
|
Caspase
|
Infection
|
Ac-YVAD-AMC is an inhibitor for caspase. Ac-YVAD-AMC inhibits bacteria-induced cell death of hypersensitive response (HR) cells .
|
-
-
- HY-N7434S
-
Diethylnitrosamine-d4; DEN-d4
|
DNA/RNA Synthesis
|
Cancer
|
N-Nitrosodiethylamine-d4 is the deuterium labeled N-Nitrosodiethylamine[1]. N-Nitrosodiethylamine (Diethylnitrosamine) is a potent hepatocarcinogenic dialkylnitrosoamine. N-Nitrosodiethylamine is mainly present in tobacco smoke, water, cheddar cheese, cured, fried meals and many alcoholic beverages. N-Nitrosodiethylamine is responsible for the changes in the nuclear enzymes associated with DNA repair/replication. N-Nitrosodiethylamine results in various tumors in all animal species. The main target organs are the nasal cavity, trachea, lung, esophagus and liver.
|
-
- HY-N7434S1
-
Diethylnitrosamine-d10; DEN-d10
|
DNA/RNA Synthesis
|
Cancer
|
N-Nitrosodiethylamine-d10 is the deuterium labeled N-Nitrosodiethylamine[1]. N-Nitrosodiethylamine (Diethylnitrosamine) is a potent hepatocarcinogenic dialkylnitrosoamine. N-Nitrosodiethylamine is mainly present in tobacco smoke, water, cheddar cheese, cured, fried meals and many alcoholic beverages. N-Nitrosodiethylamine is responsible for the changes in the nuclear enzymes associated with DNA repair/replication. N-Nitrosodiethylamine results in various tumors in all animal species. The main target organs are the nasal cavity, trachea, lung, esophagus and liver.
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- HY-W017232
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p-Quinanisole
|
Biochemical Assay Reagents
|
Others
|
6-Methoxyquinoline consists of a quinoline ring system with a methoxy group attached to the sixth carbon atom. This compound occurs naturally in certain plants, such as tobacco and tea, and has been shown to have biological activities, including antioxidant, anti-inflammatory and antitumor properties. Furthermore, 6-Methoxyquinoline can be used as a building block for the synthesis of other organic compounds, especially those with potential pharmaceutical applications. Due to its ability to bind nucleic acids and proteins, it can also be used as a fluorescent probe in biochemical and biomedical research.
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-
- HY-41404
-
2H-1,3-benzodioxole-5-carboxylic acid
|
Cytochrome P450
Interleukin Related
EGFR
IGF-1R
|
Infection
Others
Cancer
|
Piperonylic acid is a natural molecule bearing a methylenedioxy function that closely mimics the structure of trans-cinnamic acid. Piperonylic Acid is a selective, mechanism-based inactivator of the trans-cinnamate 4-Hydroxylase. Piperonylic acid has anticancer, antioxidant and antibacterial activities .
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Cat. No. |
Product Name |
Type |
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- HY-W017232
-
p-Quinanisole
|
Biochemical Assay Reagents
|
6-Methoxyquinoline consists of a quinoline ring system with a methoxy group attached to the sixth carbon atom. This compound occurs naturally in certain plants, such as tobacco and tea, and has been shown to have biological activities, including antioxidant, anti-inflammatory and antitumor properties. Furthermore, 6-Methoxyquinoline can be used as a building block for the synthesis of other organic compounds, especially those with potential pharmaceutical applications. Due to its ability to bind nucleic acids and proteins, it can also be used as a fluorescent probe in biochemical and biomedical research.
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- HY-W127341
-
|
Biochemical Assay Reagents
|
Phytanic acid methyl esteris an esterified form of long-chain fatty acid methyl esters and phytanic acid, which has been found in Greek tobacco.
|
Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P3825
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CCAP
|
Peptides
|
Cardiovascular Disease
|
Crustacean cardioactive peptide (CCAP) is a insect cardioregulatory peptides that contmns 9 amino acid, first isolated from the tobacco hawkmoth, Manduca sexta. There are two cystemes at pnsttons 3 and 9 forming a disulfide bridge and the carboxyl-terminns is amldated .
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- HY-P10246
-
|
Peptides
|
Inflammation/Immunology
|
Hemoglobin 64-76 is a T cell inducing determinant, that binds to two different MHC class II molecules in distinct registers and lengths .
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- HY-P2717
-
|
Caspase
|
Infection
|
Ac-YVAD-AMC is an inhibitor for caspase. Ac-YVAD-AMC inhibits bacteria-induced cell death of hypersensitive response (HR) cells .
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Optimized version of product available:
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Cat. No. |
Product Name |
Chemical Structure |
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- HY-W001909S
-
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Myosmine-d4 is the deuterium labeled Myosmine. Myosmine, a specific tobacco alkaloid in nuts and nut products, has low affinity for a4b2 nicotinic acetylcholinergic receptors (nAChR) with a Ki of 3300 nM[1][2].
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-
-
- HY-Y0507S
-
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DL-Serine-2,3,3-d3 is the deuterium labeled DL-Serine. DL-Serine, a fundamental metabolite, is a mixture of D-Serine and L-Serine. DL-Serine has antiviral activity against the multiplication of tobacco mosaic virus (TMV)[1].
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-
-
- HY-Y0189S
-
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Methyl Salicylate-d4 is the deuterium labeled Methyl Salicylate[1]. Methyl Salicylate (Wintergreen oil) is a topical analgesic and anti-inflammatory agent. Also used as a pesticide, a denaturant, a fragrance ingredient, and a flavoring agent in food and tobacco products[2]. A systemic acquired resistance (SAR) signal in tobacco[3]. A topical nonsteroidal anti-inflammatory agent (NSAID). Methyl salicylate lactoside is a COX inhibitor[5].
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-
- HY-W004515S
-
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3-Pyridylacetic acid-d4 (hydrochloride) is the deuterium labeled 3-Pyridylacetic acid hydrochloride[1]. 3-Pyridineacetic acid hydrochloride is a higher homologue of nicotinic acid, a breakdown product of nicotine (and other tobacco alkaloids)[2][3].
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-
- HY-W718796
-
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DL-Serine- 15N is 15N-labeled DL-Serine (HY-Y0507) DL-Serine, a fundamental metabolite, is a mixture of D-Serine and L-Serine. DL-Serine has antiviral activity against the multiplication of tobacco mosaic virus (TMV).
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-
-
- HY-N7434S
-
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N-Nitrosodiethylamine-d4 is the deuterium labeled N-Nitrosodiethylamine[1]. N-Nitrosodiethylamine (Diethylnitrosamine) is a potent hepatocarcinogenic dialkylnitrosoamine. N-Nitrosodiethylamine is mainly present in tobacco smoke, water, cheddar cheese, cured, fried meals and many alcoholic beverages. N-Nitrosodiethylamine is responsible for the changes in the nuclear enzymes associated with DNA repair/replication. N-Nitrosodiethylamine results in various tumors in all animal species. The main target organs are the nasal cavity, trachea, lung, esophagus and liver.
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-
-
- HY-N7434S1
-
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N-Nitrosodiethylamine-d10 is the deuterium labeled N-Nitrosodiethylamine[1]. N-Nitrosodiethylamine (Diethylnitrosamine) is a potent hepatocarcinogenic dialkylnitrosoamine. N-Nitrosodiethylamine is mainly present in tobacco smoke, water, cheddar cheese, cured, fried meals and many alcoholic beverages. N-Nitrosodiethylamine is responsible for the changes in the nuclear enzymes associated with DNA repair/replication. N-Nitrosodiethylamine results in various tumors in all animal species. The main target organs are the nasal cavity, trachea, lung, esophagus and liver.
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