Sodium 3-methyl-2-oxobutanoate-¹³C₅

Name: Sodium 3-methyl-2-oxobutanoate- 13 C 5
Brand: MedChemExpress
SKU: HY-W006057AS16
Rating: 4.5 (1 reviews)

Cat. No.: HY-W006057AS16 Purity: 99.00%: FAQs
Data Sheet SDS COA Handling Instructions

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Sodium 3-methyl-2-oxobutanoate-¹³C₅ is the ¹³C labeled Sodium 3-methyl-2-oxobutanoate[1]. Sodium 3-methyl-2-oxobutanoate is a precursor of pantothenic acid in Escherichia coli[2][3][4].

For research use only. We do not sell to patients.

Sodium 3-methyl-2-oxobutanoate-<sup>13</sup>C<sub>5</sub> Chemical Structure

Sodium 3-methyl-2-oxobutanoate-¹³C₅ Chemical Structure

CAS No. : 1173018-24-0

Size	Price	Stock	Quantity
5 mg	USD 180	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 250	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of Sodium 3-methyl-2-oxobutanoate-¹³C₅:

Sodium 3-methyl-2-oxobutanoate In-stock

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Sodium 3-methyl-2-oxobutanoate-¹³C₅ is the ¹³C labeled Sodium 3-methyl-2-oxobutanoate[1]. Sodium 3-methyl-2-oxobutanoate is a precursor of pantothenic acid in Escherichia coli[2][3][4].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

143.06

Formula

¹³C₅H₇NaO₃

CAS No.

1173018-24-0

Appearance

Solid

Color

White to off-white

SMILES

[13CH3][13CH]([13CH3])[13C]([13C](O[Na])=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

H₂O : ≥ 100 mg/mL (699.01 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	6.9901 mL	34.9504 mL	69.9007 mL
5 mM	1.3980 mL	6.9901 mL	13.9801 mL
10 mM	0.6990 mL	3.4950 mL	6.9901 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.00%

Select Batch:

Data Sheet (275 KB) SDS (393 KB)

COA (252 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]

[2]. MAAS WK, et al. alpha-Ketoisovaleric acid, a precursor of pantothenic acid in Escherichia coli. J Bacteriol. 1953 Apr;65(4):388-93. [Content Brief]

[3]. Schauder P, et al. Oral administration of alpha-ketoisovaleric acid or valine in humans: blood kinetics and biochemical effects. J Lab Clin Med. 1984 Apr103(4):597-605. [Content Brief]

[4]. Coitinho AS, et al. Pharmacological evidence that alpha-ketoisovaleric acid induces convulsions through GABAergic and glutamatergic mechanisms in rats. Brain Res. 2001 Mar 9894(1):68-73. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	6.9901 mL	34.9504 mL	69.9007 mL	174.7519 mL
	5 mM	1.3980 mL	6.9901 mL	13.9801 mL	34.9504 mL
	10 mM	0.6990 mL	3.4950 mL	6.9901 mL	17.4752 mL
	15 mM	0.4660 mL	2.3300 mL	4.6600 mL	11.6501 mL
	20 mM	0.3495 mL	1.7475 mL	3.4950 mL	8.7376 mL
	25 mM	0.2796 mL	1.3980 mL	2.7960 mL	6.9901 mL
	30 mM	0.2330 mL	1.1650 mL	2.3300 mL	5.8251 mL
	40 mM	0.1748 mL	0.8738 mL	1.7475 mL	4.3688 mL
	50 mM	0.1398 mL	0.6990 mL	1.3980 mL	3.4950 mL
	60 mM	0.1165 mL	0.5825 mL	1.1650 mL	2.9125 mL
	80 mM	0.0874 mL	0.4369 mL	0.8738 mL	2.1844 mL
	100 mM	0.0699 mL	0.3495 mL	0.6990 mL	1.7475 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.