2. GPCR/G Protein Neuronal Signaling
  3. mAChR
  4. Talsaclidine

Talsaclidine is a muscarinic agonist with preferential neuron-stimulating properties. Talsaclidine is a full agonist at the M1 subtype, and as a partial agonist at the M2 and M3 subtypes. Talsaclidine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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Talsaclidine Chemical Structure

Talsaclidine Chemical Structure

CAS No. : 147025-53-4

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1 mg USD 260 In-stock
5 mg USD 590 In-stock
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Talsaclidine Related Antibodies

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Description

Talsaclidine is a muscarinic agonist with preferential neuron-stimulating properties. Talsaclidine is a full agonist at the M1 subtype, and as a partial agonist at the M2 and M3 subtypes[1][2][3][4]. Talsaclidine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC50 & Target

mAChR2

 

mAChR3

 

Clinical Trial
Molecular Weight

165.23

Formula

C10H15NO
CAS No.
Appearance

Liquid

Color

Light yellow to yellow

SMILES

C#CCO[C@@H]1[C@@H]2CCN(CC2)C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 5 mg/mL (30.26 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.0522 mL 30.2609 mL 60.5217 mL
5 mM 1.2104 mL 6.0522 mL 12.1043 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥98.0%

COA (244 KB) Elemental Analysis Report (102 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 6.0522 mL 30.2608 mL 60.5217 mL 151.3042 mL
5 mM 1.2104 mL 6.0522 mL 12.1043 mL 30.2608 mL
10 mM 0.6052 mL 3.0261 mL 6.0522 mL 15.1304 mL
15 mM 0.4035 mL 2.0174 mL 4.0348 mL 10.0869 mL
20 mM 0.3026 mL 1.5130 mL 3.0261 mL 7.5652 mL
25 mM 0.2421 mL 1.2104 mL 2.4209 mL 6.0522 mL
30 mM 0.2017 mL 1.0087 mL 2.0174 mL 5.0435 mL
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Talsaclidine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Talsaclidine147025-53-4mAChRMuscarinic acetylcholine receptorInhibitorinhibitorinhibit

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