Tamsulosin hydrochloride (Synonyms: (R)-(-)-YM12617; LY253351)

Cat. No.: HY-B0661A Purity: 99.81%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Tamsulosin hydrochloride ((R)-(-)-YM12617) is an inhibitor of α₁-adrenergic receptor. Tamsulosin hydrochloride is used for the research of prostatic hyperplasia. Tamsulosin hydrochloride attenuates abdominal aortic aneurysm growth in animal models.

For research use only. We do not sell to patients.

Tamsulosin hydrochloride Chemical Structure

CAS No. : 106463-17-6

Size	Price	Stock	Quantity
5 mg	USD 38	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 60	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 120	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 180	In-stock	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of Tamsulosin hydrochloride:

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α adrenergic receptor β adrenergic receptor

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Description

IC₅₀ & Target^[1]

α1-adrenergic receptor

Clinical Trial

Molecular Weight

444.97

Formula

C₂₀H₂₉ClN₂O₅S

CAS No.

106463-17-6

Appearance

Solid

Color

White to off-white

SMILES

O=S(C1=CC(C[C@H](NCCOC2=CC=CC=C2OCC)C)=CC=C1OC)(N)=O.Cl

Structure Classification

Initial Source

Endogenous metabolite

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility

In Vitro:

DMSO : 62.5 mg/mL (140.46 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.2473 mL	11.2367 mL	22.4734 mL
5 mM	0.4495 mL	2.2473 mL	4.4947 mL
10 mM	0.2247 mL	1.1237 mL	2.2473 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.81%

Select Batch:

Data Sheet (271 KB) SDS (252 KB)

COA (248 KB) HNMR (283 KB) LCMS (84 KB)

Handling Instructions (2659 KB)

References

[1]. Christopher Chapple, et al. Tamsulosin: an overview. World J Urol. 2002 Apr;19(6):397-404. [Content Brief]

[2]. William G. Montgomery, BA, et al. Tamsulosin Attenuates Abdominal Aortic Aneurysm Growth. Surgery. 2018 Nov; 164(5): 1087-1092. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.2473 mL	11.2367 mL	22.4734 mL	56.1836 mL
	5 mM	0.4495 mL	2.2473 mL	4.4947 mL	11.2367 mL
	10 mM	0.2247 mL	1.1237 mL	2.2473 mL	5.6184 mL
	15 mM	0.1498 mL	0.7491 mL	1.4982 mL	3.7456 mL
	20 mM	0.1124 mL	0.5618 mL	1.1237 mL	2.8092 mL
	25 mM	0.0899 mL	0.4495 mL	0.8989 mL	2.2473 mL
	30 mM	0.0749 mL	0.3746 mL	0.7491 mL	1.8728 mL
	40 mM	0.0562 mL	0.2809 mL	0.5618 mL	1.4046 mL
	50 mM	0.0449 mL	0.2247 mL	0.4495 mL	1.1237 mL
	60 mM	0.0375 mL	0.1873 mL	0.3746 mL	0.9364 mL
	80 mM	0.0281 mL	0.1405 mL	0.2809 mL	0.7023 mL
	100 mM	0.0225 mL	0.1124 mL	0.2247 mL	0.5618 mL

Tamsulosin hydrochloride Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tamsulosin106463-17-6(R)-(-)-YM12617 LY253351LY253351LY 253351LY-253351Adrenergic ReceptorEndogenous MetaboliteBeta ReceptorInhibitorinhibitorinhibit

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Tamsulosin hydrochloride (Synonyms: (R)-(-)-YM12617; LY253351)

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Other Forms of Tamsulosin hydrochloride:

Tamsulosin hydrochloride Related Antibodies

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References

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Complete Stock Solution Preparation Table

Tamsulosin hydrochloride Related Classifications

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