2. Apoptosis Metabolic Enzyme/Protease
  3. Apoptosis Endogenous Metabolite
  4. Taurochenodeoxycholic acid-d5 sodium

Taurochenodeoxycholic acid-d5 sodium  (Synonyms: 12-Deoxycholyltaurine-d5 (sodium))

Cat. No.: HY-N1429S1
COA Handling Instructions

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Taurochenodeoxycholic acid-d5 (sodium) is the deuterium labeled Taurochenodeoxycholic acid sodium. Taurochenodeoxycholic acid sodium salt (12-Deoxycholyltaurine sodium salt) is one of the main bioactive substances of animals' bile acid. Taurochenodeoxycholic acid induces apoptosis and shows obvious anti-inflammatory and immune regulation properties[1][2].

For research use only. We do not sell to patients.

Taurochenodeoxycholic acid-d<sub>5</sub> sodium Chemical Structure

Taurochenodeoxycholic acid-d5 sodium Chemical Structure

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Based on 1 publication(s) in Google Scholar

Other Forms of Taurochenodeoxycholic acid-d5 sodium:

Taurochenodeoxycholic acid-d5 sodium Related Antibodies

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Description

Taurochenodeoxycholic acid-d5 (sodium) is the deuterium labeled Taurochenodeoxycholic acid sodium. Taurochenodeoxycholic acid sodium salt (12-Deoxycholyltaurine sodium salt) is one of the main bioactive substances of animals' bile acid. Taurochenodeoxycholic acid induces apoptosis and shows obvious anti-inflammatory and immune regulation properties[1][2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Taurochenodeoxycholic acid-d5 sodium Related Antibodies
Molecular Weight

526.72

Formula

C26H39D5NNaO6S
Appearance

Solid

Color

White to off-white

SMILES

C[C@]12[C@]([H])([C@]3([C@@]([H])([C@]4(C)[C@]([H])(C[C@H]3O)C([2H])([C@]([2H])(O)C([2H])(C4)[2H])[2H])CC2)[H])CC[C@@]1([C@@H](CCC(NCCS(=O)(O[Na])=O)=O)C)[H]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (189.85 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8985 mL 9.4927 mL 18.9854 mL
5 mM 0.3797 mL 1.8985 mL 3.7971 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 98.12%

COA (251 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.8985 mL 9.4927 mL 18.9854 mL 47.4636 mL
5 mM 0.3797 mL 1.8985 mL 3.7971 mL 9.4927 mL
10 mM 0.1899 mL 0.9493 mL 1.8985 mL 4.7464 mL
15 mM 0.1266 mL 0.6328 mL 1.2657 mL 3.1642 mL
20 mM 0.0949 mL 0.4746 mL 0.9493 mL 2.3732 mL
25 mM 0.0759 mL 0.3797 mL 0.7594 mL 1.8985 mL
30 mM 0.0633 mL 0.3164 mL 0.6328 mL 1.5821 mL
40 mM 0.0475 mL 0.2373 mL 0.4746 mL 1.1866 mL
50 mM 0.0380 mL 0.1899 mL 0.3797 mL 0.9493 mL
60 mM 0.0316 mL 0.1582 mL 0.3164 mL 0.7911 mL
80 mM 0.0237 mL 0.1187 mL 0.2373 mL 0.5933 mL
100 mM 0.0190 mL 0.0949 mL 0.1899 mL 0.4746 mL
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Taurochenodeoxycholic acid-d5 sodium Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Taurochenodeoxycholic acid-d512-Deoxycholyltaurine-d5ApoptosisEndogenous MetaboliteInhibitorinhibitorinhibit

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