1. Others
  2. Isotope-Labeled Compounds
  3. Trimethyllysine-d9

Trimethyllysine-d9is the deuterium labeledTrimethyllysine(HY-143711). Trimethyllysine is an important post-translationally modified amino acid, involving in carnitine biosynthesis and epigenetic processes.

For research use only. We do not sell to patients.

Trimethyllysine-d<sub>9</sub> Chemical Structure

Trimethyllysine-d9 Chemical Structure

CAS No. : 1182037-78-0

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2500 μg USD 570 In-stock

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Based on 1 publication(s) in Google Scholar

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Description

Trimethyllysine-d9is the deuterium labeledTrimethyllysine(HY-143711)[1]. Trimethyllysine is an important post-translationally modified amino acid, involving in carnitine biosynthesis and epigenetic processes[2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

197.32

Formula

C9H11D9N2O2

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

[2H]C([2H])([2H])[N+](C([2H])([2H])[2H])(C([2H])([2H])[2H])CCCC[C@H](N)C([O-])=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (506.79 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.0679 mL 25.3395 mL 50.6791 mL
5 mM 1.0136 mL 5.0679 mL 10.1358 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 5.0679 mL 25.3395 mL 50.6791 mL 126.6977 mL
5 mM 1.0136 mL 5.0679 mL 10.1358 mL 25.3395 mL
10 mM 0.5068 mL 2.5340 mL 5.0679 mL 12.6698 mL
15 mM 0.3379 mL 1.6893 mL 3.3786 mL 8.4465 mL
20 mM 0.2534 mL 1.2670 mL 2.5340 mL 6.3349 mL
25 mM 0.2027 mL 1.0136 mL 2.0272 mL 5.0679 mL
30 mM 0.1689 mL 0.8447 mL 1.6893 mL 4.2233 mL
40 mM 0.1267 mL 0.6335 mL 1.2670 mL 3.1674 mL
50 mM 0.1014 mL 0.5068 mL 1.0136 mL 2.5340 mL
60 mM 0.0845 mL 0.4223 mL 0.8447 mL 2.1116 mL
80 mM 0.0633 mL 0.3167 mL 0.6335 mL 1.5837 mL
100 mM 0.0507 mL 0.2534 mL 0.5068 mL 1.2670 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Trimethyllysine-d9 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Trimethyllysine-d9
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HY-143711S
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