Viloxazine hydrochloride (Synonyms: Viloxazin hydrochloride; Emovit hydrochloride)

Cat. No.: HY-125784 Purity: ≥98.0%: FAQs
Data Sheet SDS COA Handling Instructions

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Viloxazine hydrochloride is the hydrochloride salt form of Viloxazine (HY-W380450). Viloxazine (Viloxazin) hydrochloride is a norepinephrine reuptake inhibitor and a potent 5-HT_2C agonist agent and 5-HT_2B antagonist, EC₅₀ for 5-HT_2C b> is 32 μM, and the IC₅₀ for 5-HT_2B is 27 μM. Viloxazine hydrochloride's mechanism of action primarily involves serotonergic and noradrenergic pathways. Viloxazine hydrochloride is used in antidepressant research.

For research use only. We do not sell to patients.

Viloxazine hydrochloride Chemical Structure

CAS No. : 35604-67-2

Size	Price	Stock	Quantity
10 mg	USD 60	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 120	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 190	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 300	In-stock	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of Viloxazine hydrochloride:

(rac)-Viloxazine-d₅ hydrochloride In-stock
(R)-Viloxazine hydrochloride Get quote
Viloxazine Get quote

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Description

Molecular Weight

273.76

Formula

C₁₃H₂₀ClNO₃

CAS No.

35604-67-2

Appearance

Solid

Color

White to off-white

SMILES

CCOC1=C(OCC2OCCNC2)C=CC=C1.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 33.33 mg/mL (121.75 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.6528 mL	18.2642 mL	36.5283 mL
5 mM	0.7306 mL	3.6528 mL	7.3057 mL
10 mM	0.3653 mL	1.8264 mL	3.6528 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: ≥98.0%

Select Batch:

Data Sheet (273 KB) SDS (392 KB)

COA (250 KB) HNMR (134 KB) LCMS (90 KB)

Handling Instructions (2659 KB)

References

[1]. Yu C, et al. New Insights into the Mechanism of Action of Viloxazine: Serotonin and Norepinephrine Modulating Properties. J Exp Pharmacol. 2020 Aug 25;12:285-300. [Content Brief]

[2]. Pinder RM, et al. Viloxazine: a review of its pharmacological properties and therapeutic efficacy in depressive illness. Drugs. 1977 Jun;13(6):401-21. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.6528 mL	18.2642 mL	36.5283 mL	91.3209 mL
	5 mM	0.7306 mL	3.6528 mL	7.3057 mL	18.2642 mL
	10 mM	0.3653 mL	1.8264 mL	3.6528 mL	9.1321 mL
	15 mM	0.2435 mL	1.2176 mL	2.4352 mL	6.0881 mL
	20 mM	0.1826 mL	0.9132 mL	1.8264 mL	4.5660 mL
	25 mM	0.1461 mL	0.7306 mL	1.4611 mL	3.6528 mL
	30 mM	0.1218 mL	0.6088 mL	1.2176 mL	3.0440 mL
	40 mM	0.0913 mL	0.4566 mL	0.9132 mL	2.2830 mL
	50 mM	0.0731 mL	0.3653 mL	0.7306 mL	1.8264 mL
	60 mM	0.0609 mL	0.3044 mL	0.6088 mL	1.5220 mL
	80 mM	0.0457 mL	0.2283 mL	0.4566 mL	1.1415 mL
	100 mM	0.0365 mL	0.1826 mL	0.3653 mL	0.9132 mL

Viloxazine hydrochloride Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Viloxazine35604-67-2ViloxazinEmovitOthersSerotonergicnoradrenergic5-HTdepressionInhibitorinhibitorinhibit

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Viloxazine hydrochloride (Synonyms: Viloxazin hydrochloride; Emovit hydrochloride)

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Complete Stock Solution Preparation Table

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