Vincanol (Synonyms: (-)-Isoeburnamine; (-)-epi-Eburnamine)

Cat. No.: HY-124925: FAQs
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Vincanol ((-)-Isoeburnamine) is a blocker of voltage-gated Na+ channels. Vincanol blocks Na⁺ currents with an IC₅₀ value of 40 μM. Vincanol has neuroprotective effect.

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Vincanol Chemical Structure

CAS No. : 19877-89-5

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Description	Vincanol ((-)-Isoeburnamine) is a blocker of voltage-gated Na+ channels. Vincanol blocks Na⁺ currents with an IC₅₀ value of 40 μM. Vincanol has neuroprotective effect^[1].
Molecular Weight	296.41
Formula	C₁₉H₂₄N₂O
CAS No.	19877-89-5
SMILES	O[C@H]1N2C3=C(CCN4[C@]3([C@](CC)(C1)CCC4)[H])C5=C2C=CC=C5
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (273 KB) Handling Instructions (2659 KB)
References	[1]. Erdo SA, et al. Vincamine and vincanol are potent blockers of voltage-gated Na+ channels. Eur J Pharmacol. 1996 Oct 24;314(1-2):69-73. [Content Brief]

Vincanol Related Classifications

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This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Vincanol19877-89-5(-)-Isoeburnamine (-)-epi-EburnamineSodium ChannelNa channelsNa+ channelsneuroprotectiveveratridinevoltage-gated Na+ channelInhibitorinhibitorinhibit

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Vincanol (Synonyms: (-)-Isoeburnamine; (-)-epi-Eburnamine)

Vincanol Related Antibodies

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Biological Activity

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References

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