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  4. Polyporaceae

Polyporaceae

 

Polyporaceae (70):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N1447
    Ganoderic acid A 81907-62-2 99.84%
    Ganoderic acid A can inhibit of the JAK-STAT3 signaling pathway, also inhibit proliferation, viability, ROS.
    Ganoderic acid A
  • HY-N0371
    Pachymic acid 29070-92-6 ≥99.0%
    Pachymic acid is a lanostrane-type triterpenoid from P. cocos. Pachymic acid inhibits Akt and ERK signaling pathways.
    Pachymic acid
  • HY-N1511
    Ganoderic acid D 108340-60-9 99.81%
    Ganoderic acid D, a highly oxygenated tetracyclic triterpenoid, is the major active component of Ganoderma lucidum. Ganoderic acid D upregulates the protein expression of SIRT3 and induces the deacetylated cyclophilin D (CypD) by SIRT3. Ganoderic acid D inhibits the energy reprogramming of colon cancer cells including glucose uptake, lactate production, pyruvate and acetyl-coenzyme production in colon cancer cells. Ganoderic acid D induces HeLa human cervical carcinoma apoptosis.
    Ganoderic acid D
  • HY-N1517
    Ganoderic acid C2 103773-62-2 99.30%
    Ganoderic acid C2 is a bioactive triterpenoid in Ganoderma lucidum. Ganoderic acid C2 possesses the potential anti-tumor bioactivity, antihistamine, anti-aging and cytotoxic effects. Ganoderic acid C2 exhibits high inhibitory activity against the rat lens aldose reductase (RLAR) with an IC50 of 3.8 µM.
    Ganoderic acid C2
  • HY-N2499
    Dehydrotumulosic acid 6754-16-1 99.67%
    Dehydrotumulosic acid is one of the effective constituents of Poria cocos. Poria cocos, a popular Chinese medicinal herb of fungal origin, has been included in many combinations with other CM herbs for its traditionally claimed activities of inducing diuresis, excreting dampness, invigorating the spleen and tranquilizing the mind and its modern pharmacological use of modulating the immune system of the body.
    Dehydrotumulosic acid
  • HY-N9366
    Tumulosic acid 508-24-7 98.31%
    Tumulosic acid, a triterpenoid, inhibits KLK5 protease activity (IC50= 14.84 μM). Tumulosic acid suppresses the proteolytic processing of LL-37 in keratinocytes at ≤10 μM.
    Tumulosic acid
  • HY-N2006
    Ganoderic acid B 81907-61-1 99.31%
    Ganoderic acid B is a triterpene isolated from a mushroom Ganoderma lucidum. Ganoderic acid B inhibits the activation of Epstein-Barr virus (EBV) antigens as telomerase inhibitor. Ganoderic acid B is a moderately active inhibitor against HIV-1 protease (IC50: 170 μM).
    Ganoderic acid B
  • HY-120140
    Ganoderic acid DM 173075-45-1 99.65%
    Ganoderic acid DM, a natural triterpenoid isolated from Ganoderma lucidum, induces DNA damage, G1 cell cycle arrest and apoptosis in human breast cancer cells. Ganoderic acid DM as a specific inhibitor of osteoclastogenesis.
    Ganoderic acid DM
  • HY-N2993
    Polyporenic acid C 465-18-9 99.80%
    Polyporenic acid C is a lanostane-type triterpenoid isolated from P. cocos. Polyporenic acid C induces cell apoptosis through the death receptor-mediated apoptotic pathway without the involvement of the mitochondria. Polyporenic acid C is promising agent for lung cancer therapy.
    Polyporenic acid C
  • HY-N2995
    Poricoic acid A 137551-38-3 ≥98.0%
    Poricoic acid A, isolated from Poria cocos, possesses anti-tumor activity. Poricoic acid A enhances melatonin inhibition of AKI-to-CKD transition by regulating Gas6/AxlNFκB/Nrf2 axis.
    Poricoic acid A
  • HY-N4124
    Poricoic acid B 137551-39-4
    Poricoic acid B, isolated from Poria cocos, possesses anti-tumor activity.
    Poricoic acid B
  • HY-N1513
    Ganoderic acid H 98665-19-1 99.68%
    Ganoderic acid H is a lanostane-type triterpene isolated from Ganoderma lucidum. Ganoderic acid H suppresses growth and invasive behavior of breast cancer cells through the inhibition of transcription factors AP-1 and NF-kappaB signaling.
    Ganoderic acid H
  • HY-N2461
    Ganoderic acid C6 105742-76-5 98.15%
    Ganoderic acid C6 has aldose reductase inhibitory activity.
    Ganoderic acid C6
  • HY-N2490
    Dehydrotrametenolic acid 6879-05-6 99.95%
    Dehydrotrametenolic acid is a sterol isolated from the sclerotium of Poria cocos. Dehydrotrametenolic acid induces apoptosis through caspase-3 pathway. Dehydrotrametenolic acid has anti-tumor activity, anti-inflammatory, anti-diabetic effects.
    Dehydrotrametenolic acid
  • HY-N2991
    Dehydropachymic acid 77012-31-8 99.94%
    Dehydropachymic acid is one of the major triterpenes isolated from Poria cocos. Dehydropachymic acid is more effective in autophagy-lysosome pathway (ALP) impaired cells rather than normal cells.
    Dehydropachymic acid
  • HY-N6036
    Ganoderic acid F 98665-15-7 99.70%
    Ganoderic acid F is a ganoderic acid. Ganoderic acid F exhibits antitumor and antimetastatic activities through inhibition of angiogenesis and alteration of proteins involving cell proliferation and/or cell death, carcinogenesis, oxidative stress, calcium signaling, and endoplasmic reticulum stress.
    Ganoderic acid F
  • HY-N2177
    3-Dehydrotrametenolic acid 29220-16-4 99.86%
    3-​Dehydrotrametenolic acid, isolated from the sclerotium of Poria cocos, is a lactate dehydrogenase (LDH) inhibitor. 3-​Dehydrotrametenolic acid promotes adipocyte differentiation in vitro and acts as an insulin sensitizer in vivo. 3-​Dehydrotrametenolic acid induces apoptosis and has anticancer activity.
    3-Dehydrotrametenolic acid
  • HY-N2221
    Ganoderal A 104700-98-3
    Ganoderal A, an oxygenated sterol from G. lucidum, is a cholesterol synthesis inhibitor.
    Ganoderal A
  • HY-W006429
    L-Uridine 26287-69-4 99.81%
    L-Uridine, isolated from the Polyporaceae fungus Poria cocos (Schw.), is an enantiomer of the normal RNA constituent D-uridine. L-uridine acts as a phosphate acceptor for nucleoside phosphotransferases.
    L-Uridine
  • HY-123100
    Ganoderic acid N 110241-19-5 99.81%
    Ganoderic acid N is a natural terpenoid isolated from the Fungus Ganoderma lucidum.
    Ganoderic acid N