Network Version
Tedizolid phosphate Data Sheet
| Product Name: | Tedizolid phosphate |
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|---|---|---|
| CAS No.: | 856867-55-5 | |
| Cat. No.: | HY-14855B | |
| MWt: | 450.32 | |
| Formula: | C17H16FN6O6P | |
| Purity : | >98% | |
| Solubility: | DMSO : ≥ 36 mg/mL (79.94 mM); H2O : 0.1 mg/mL (0.22 mM; Need ultrasonic) | |
| Mechanisms: | Target: Infection | |
| Biological Activity: | ||
| Tedizolid phosphate (TR-701FA) is a novel oxazolidinone with activity against Gram-positive pathogens. In Vitro: Tedizolid phosphate (TR-701FA; 0.25 μg/mL) inhibits all 28 clinical isolates of PRSP, and is 4-fold more potent than linezolid against PRSP[1]. In Vivo: For mice infected with PSSP type III, the 100% survival rate is achieved with tedizolid phosphate (TR-701FA) at a minimum total daily dose of 10 mg/kg. Lungs of infected mice treated with tedizolid phosphate show less severe inflammation and edema, as indicated by the mean scores for inflammation and edema[1]. | ||
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