1. Anti-infection
  2. Bacterial
  3. Tedizolid phosphate

Tedizolid phosphate (Synonyms: TR-701FA)

Cat. No.: HY-14855B Purity: 98.20%
Handling Instructions

Tedizolid phosphate (TR-701FA) is a novel oxazolidinone with activity against Gram-positive pathogens.

For research use only. We do not sell to patients.

Tedizolid phosphate Chemical Structure

Tedizolid phosphate Chemical Structure

CAS No. : 856867-55-5

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 92 In-stock
Estimated Time of Arrival: December 31
5 mg USD 84 In-stock
Estimated Time of Arrival: December 31
10 mg USD 120 In-stock
Estimated Time of Arrival: December 31
50 mg USD 180 In-stock
Estimated Time of Arrival: December 31
100 mg USD 252 In-stock
Estimated Time of Arrival: December 31
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Customer Review

Based on 6 publication(s) in Google Scholar

Other Forms of Tedizolid phosphate:

Top Publications Citing Use of Products
  • Biological Activity

  • Protocol

  • Purity & Documentation

  • References

  • Customer Review


Tedizolid phosphate (TR-701FA) is a novel oxazolidinone with activity against Gram-positive pathogens.

In Vitro

Tedizolid phosphate (TR-701FA; 0.25 μg/mL) inhibits all 28 clinical isolates of PRSP, and is 4-fold more potent than linezolid against PRSP[1].

In Vivo

For mice infected with PSSP type III, the 100% survival rate is achieved with tedizolid phosphate (TR-701FA) at a minimum total daily dose of 10 mg/kg. Lungs of infected mice treated with tedizolid phosphate show less severe inflammation and edema, as indicated by the mean scores for inflammation and edema[1].

Clinical Trial
Molecular Weight







O=C1O[[email protected]@H](COP(O)(O)=O)CN1C2=CC=C(C3=CC=C(C4=NN(C)N=N4)N=C3)C(F)=C2


Room temperature in continental US; may vary elsewhere.

Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 36 mg/mL (79.94 mM)

H2O : 0.1 mg/mL (0.22 mM; Need ultrasonic)

*"≥" means soluble, but saturation unknown.

Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2206 mL 11.1032 mL 22.2064 mL
5 mM 0.4441 mL 2.2206 mL 4.4413 mL
10 mM 0.2221 mL 1.1103 mL 2.2206 mL
*Please refer to the solubility information to select the appropriate solvent.
Animal Administration

To induce a systemic S. pneumoniae infection, male ICR mice (weight, 18 to 20 g) are inoculated intraperitoneally with 1 of 4 PRSP isolates (DR9, DR10, DR11, or DR14) suspended in 10% mucin. The suspension contained sufficient bacteria to kill 100% of untreated control mice. At 1 h postinfection, mice receives a single dose of either tedizolid phosphate or linezolid, and survival is assessed daily for 7 days postinfection. Treatments are delivered both orally and intravenously at each of four doses (40 mg/kg of body weight, 13.33 mg/kg, 4.44 mg/kg, and 1.48 mg/kg), with 8 mice per group defined by dose, delivery method, and infecting strain. The 50% effective dose (ED50), i.e., the dose allowing survival of 50% of the infected mice, is calculated for each delivery route using probit analysis.

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

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