2. Recombinant Proteins
  3. Cytokines and Growth Factors
  4. Neurotrophic Factors
  5. Ciliary Neurotrophic Factor Receptor (CNTFR)

Ciliary Neurotrophic Factor Receptor (CNTFR)

Recombinant Protein Expression Service

Ciliary Neurotrophic Factor Receptor (CNTFR)

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Cat. No. Product Name / Synonyms Species Source
  • HY-P76275
    CNTFR alpha Protein, Human (sf9, His)

    Ciliary neurotrophic factor receptor subunit alpha; CNTFR-alpha

    		Human Sf9 insect cells
    CNTFR alpha Protein, crucial in protein folding, binds cytosolic chaperonin (c-CPN) and facilitates transfer of target proteins. It aids nascent polypeptide chains' folding amidst diverse pathways. Structurally, PFDN1 forms a heterohexamer with two PFD-alpha and four PFD-beta subunits. Additionally, CNTFR alpha Protein serves as a receptor for the neurotropic cytokine CLCF1/CLC and CRLF1/CLF-1 heterodimer. It interacts with IL6ST/GP130 and IL27RA/WSX1 for humanin binding. Furthermore, it forms a heterotrimer with LIFR and IL6ST, interacting with SORL1 and potentially promoting internalization and lysosomal degradation. CNTFR alpha Protein, Human (sf9, His) is the recombinant human-derived CNTFR alpha protein, expressed by Sf9 insect cells, with C-His labeled tag. The total length of CNTFR alpha Protein, Human (sf9, His) is 324 a.a., with molecular weight of 45-48 KDa.
  • HY-P76276
    CNTFR alpha Protein, Rat (sf9, His)

    Ciliary neurotrophic factor receptor subunit alpha; CNTFR-alpha

    		Rat Sf9 insect cells
    CNTFR alpha protein is pivotal in binding to ciliary neurotrophic factor (CNTF), ensuring receptor specificity through its alpha subunit. It forms a heterotrimeric complex with LIFR and IL6ST, contributing to a functional receptor. CNTFR alpha also interacts with the CLCF1/CLC and CRLF1/CLF-1 heterodimer. Whether alone or with the CLCF1-CRLF1 heterodimer, CNTFR alpha engages with SORL1, potentially facilitating internalization and lysosomal degradation through this interaction. CNTFR alpha Protein, Rat (sf9, His) is the recombinant rat-derived CNTFR alpha protein, expressed by Sf9 insect cells, with C-His labeled tag. The total length of CNTFR alpha Protein, Rat (sf9, His) is 346 a.a., with molecular weight of ~48 KDa.
Cat. No. Product Name Effect Purity