1. Screening Libraries
  2. Peptidomimetic Library

Peptidomimetic Library

Cat. No.: HY-L033
Library Contents: XLSX PDF SDF

Peptidomimetics are compounds whose essential elements (pharmacophore) mimic a natural peptide or protein in 3D space and which retain the ability to interact with the biological target and produce the same biological effect. Peptidomimetics are designed to circumvent some of the problems associated with a natural peptide: e.g. stability against proteolysis (duration of activity) and poor bioavailability. Certain other properties, such as receptor selectivity or potency, often can be substantially improved. The design and synthesis of peptidomimetics are most important because of the dominant position peptide and protein-protein interactions play in molecular recognition and signaling, especially in living systems. Hence mimics have great potential in drug discovery.

MCE Peptidomimetic Library contains 379 compounds including peptoid, α-helix mimetics, β-turn/sheets mimetics, etc. This library is an indispensable tool of structure-activity relationships in drug discovery.

MCE Peptidomimetic Library can be supplied as pre-dissolved Solutions or Solid. For pre-dissolved solutions in this library, there are 309 compounds supplied in 10 mM solution and 5 compounds supplied in 2 mM solution.

For pre-dissolved solutions, 10 mM for compounds with the solubility not lower than 10 mM, and 2 mM for compounds with solubility between 2 mM and 10 mM.

  • 96-well Plate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
Size (Pre-dissolved Solution or Solid) Price Stock
30 μL/well Solution

10 mM and 2 mM
Pre-dissolved Solution

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50 μL/well Solution

10 mM and 2 mM
Pre-dissolved Solution

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100 μL/well Solution

10 mM and 2 mM
Pre-dissolved Solution

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2 × 100 μL/well Solution

10 mM and 2 mM
Pre-dissolved Solution

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Description
& Advantages

•   A unique collection of 379 compounds that act as substitutes for peptides in their interaction with receptors for drug discovery.

•   In contrast to natural peptides, compounds have high affinity and selectivity, high absorbent and metabolic stability and no immunogenicity.

•   Peptoid, α-helixmimetics, β-turn/sheets mimetics and compounds target protein-protein interactions are included.

•   A useful tool for the discovery of peptide-like drugs.

•   More detailed compound information with structure, IC50, and other chemical & biological data.

•   NMR and HPLC validated ensure high purity.

•   All compounds are in stock and continuously updated.

Product Details
Formulation:
A collection of 379 compounds supplied as pre-dissolved Solutions or Solid
Solution: 309 compounds supplied in 10 mM solution, 5 compounds supplied in 2 mM solution.
Container:
96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
Storage:
-80°C
Shipping:
Blue ice
Documentation

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    Peptidomimetic Library
    Cat. No.:
    HY-L033
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    • 96-well Plate with Peelable Foil Seal
    • 96-well Storage Tubes with Rack