2. Recombinant Proteins
  3. Receptor Proteins
  4. Siglec
  5. Myelin Associated Glycoprotein (MAG/Siglec-4a)

Myelin Associated Glycoprotein (MAG/Siglec-4a)

Recombinant Protein Expression Service

Myelin Associated Glycoprotein (MAG/Siglec-4a)

Related Products

XLSX 3.94 KB

Subscribe Now to the List of Recombinant Proteins

Cat. No. Product Name / Synonyms Species Source
  • HY-P70318
    MAG/Siglec-4a Protein, Human (HEK293, His)

    rHuMyelin-associated glycoprotein/MAG, His; Myelin-Associated Glycoprotein; Siglec-4a; MAG; GMA

    		Human HEK293
    MAG/Siglec-4a is an adhesion molecule that binds to neuronal gangliosides, RTN4R, and RTN4RL2, promoting myelination interactions. Although not important for initial myelination, it may maintain axonal myelination and protect motor neurons, especially after injury, through interactions with RTN4R and RTN4RL2. MAG/Siglec-4a Protein, Human (HEK293, His) is the recombinant human-derived MAG/Siglec-4a protein, expressed by HEK293 , with C-6*His labeled tag. The total length of MAG/Siglec-4a Protein, Human (HEK293, His) is 497 a.a., with molecular weight of 84-108 kDa.
  • HY-P70319
    MAG/Siglec-4a Protein, Mouse (HEK293, His)

    rMuMyelin-associated glycoprotein/MAG, His; Myelin-Associated Glycoprotein; MAG; Siglec-4a

    		Mouse HEK293
    MAG/Siglec-4a protein mediates myelin cell-neuron interactions by binding to gangliosides, RTN4R, and RTN4RL2. It maintains normal axonal myelination and protects motor neurons from apoptosis following injury. MAG/Siglec-4a Protein, Mouse (HEK293, His) is the recombinant mouse-derived MAG/Siglec-4a protein, expressed by HEK293 , with C-6*His labeled tag. The total length of MAG/Siglec-4a Protein, Mouse (HEK293, His) is 497 a.a., with molecular weight of 70-120 kDa.
  • HY-P70319A
    MAG/Siglec-4a Protein, Mouse (HEK293, His, solution)

    rMuMyelin-associated glycoprotein/MAG, His; Myelin-Associated Glycoprotein; MAG; Siglec-4a

    		Mouse HEK293
    The MAG/Siglec-4a protein mediates myelinating cell-neuron interactions by binding to gangliosides, RTN4R, and RTN4RL2. It maintains normal axon myelination and protects motoneurons from apoptosis after injury. It prevents degeneration of myelinated axons in adults by binding to gangliosides. Moreover, it inhibits neurite outgrowth by interacting with RTN4R, RTN4RL2, and gangliosides. It can exist as a monomer or homodimer and interacts with BSG isoform 2. MAG/Siglec-4a Protein, Mouse (HEK293, His, solution) is the recombinant mouse-derived MAG/Siglec-4a protein, expressed by HEK293, with C-6*His labeled tag. The total length of MAG/Siglec-4a Protein, Mouse (HEK293, His, solution) is 497 a.a., with molecular weight of 70-120 kDa.
  • HY-P73833
    MAG/Siglec-4a Protein, Human (HEK293, Fc)

    Myelin-Associated Glycoprotein; Siglec-4a; MAG; GMA

    		Human HEK293
    MAG/Siglec-4a is an adhesion molecule that binds to neuronal gangliosides, RTN4R, and RTN4RL2, promoting myelination interactions. Although not important for initial myelination, it may maintain axonal myelination and protect motor neurons, especially after injury, through interactions with RTN4R and RTN4RL2. MAG/Siglec-4a Protein, Human (HEK293, Fc) is the recombinant human-derived MAG/Siglec-4a protein, expressed by HEK293 , with C-hFc labeled tag. The total length of MAG/Siglec-4a Protein, Human (HEK293, Fc) is 516 a.a., with molecular weight of ~113 kDa.
  • HY-P78207
    MAG/Siglec-4a Protein, Human (Biotinylated, HEK293, His-Avi)

    MAG; Siglec4a; Siglec-4a; S-MAG; GMA

    		Human HEK293
    MAG/Siglec-4a, an adhesion molecule, binds to neuronal gangliosides, RTN4R, and RTN4RL2, facilitating myelination interactions. Although not vital for initial myelination, it crucially maintains axon myelination and protects motoneurons, especially post-injury, likely via interactions with RTN4R and RTN4RL2. In adults, MAG/Siglec-4a prevents myelinated axon degeneration by binding to axon cell membrane gangliosides. It acts as a negative regulator of neurite outgrowth, inhibiting axon growth by preferentially binding to alpha-2,3-linked sialic acid and interacting with RTN4R, RTN4RL2, gangliosides, and BSG isoform 2, contributing to its intricate role in modulating neuronal responses and axonal dynamics. MAG/Siglec-4a Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived MAG/Siglec-4a protein, expressed by HEK293, with C-Avi, C-His labeled tag. The total length of MAG/Siglec-4a Protein, Human (Biotinylated, HEK293, His-Avi) is 497 a.a., with molecular weight of 78-85 kDa.
Cat. No. Product Name Effect Purity