2. Recombinant Proteins
  3. Cytokines and Growth Factors Receptor Proteins Enzymes & Regulators
  4. Ephrin/Eph Family Receptor Tyrosine Kinases Protein Tyrosine Kinases
  5. Eph Receptors

Eph Receptors

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Eph proteins belong to the superfamily of transmembrane receptor tyrosine kinases. Eph receptors have been conserved in a variety of eukaryotic species from Caenorhabditis elegans to human. Eph receptors can be classified into EphA or EphB subfamil

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Cat. No. Product Name / Synonyms Species Source
  • HY-P72991
    EphA2 Protein, Human (sf9, His-GST)

    Ephrin type-A receptor 2; Epithelial cell kinase; EPHA2; ECK

    		Human Sf9 insect cells
    EphA2 protein is a receptor tyrosine kinase that participates in bidirectional signaling with various ephrin A ligands, affecting cell migration, adhesion, proliferation and differentiation. It regulates cell adhesion and differentiation by interacting with DSG1 and inhibiting the ERK1/ERK2 signaling pathway. EphA2 Protein, Human (sf9, His-GST) is the recombinant human-derived EphA2 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of EphA2 Protein, Human (sf9, His-GST) is 392 a.a., with molecular weight of ~62 kDa.
  • HY-P72992
    EphA2 Protein, Human (Biotinylated, HEK293, His-Avi)

    Ephrin type-A receptor 2; Epithelial cell kinase; EPHA2; ECK

    		Human HEK293
    The EphA2 protein is an important member of the ephrin receptor subfamily that mediates developmental events, particularly in the nervous system. It has a single kinase domain and an extracellular region that binds ephrin-A ligands. EphA2 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived EphA2 protein, expressed by HEK293 , with C-6*His, C-Avi labeled tag. The total length of EphA2 Protein, Human (Biotinylated, HEK293, His-Avi) is 511 a.a., with molecular weight of ~59.4 kDa.
  • HY-P73001
    EphB2 Protein, Human (HEK293, His-Fc)

    EPHB2; Ephrin type-B receptor 2; EK5; DRT; EPHT3; ERK; HEK5; TYRO5

    		Human HEK293
    EphB2 protein is a receptor tyrosine kinase that participates in bidirectional signaling with the transmembrane ephrin B ligand. It guides commissural axons in the developing cerebral cortex, efferent growth cones of the inner ear, and retinal ganglion cell axons. EphB2 Protein, Human (HEK293, His-Fc) is the recombinant human-derived EphB2 protein, expressed by HEK293 , with C-hFc, C-8*His labeled tag. The total length of EphB2 Protein, Human (HEK293, His-Fc) is 525 a.a., with molecular weight of approximately 95 kDa.
  • HY-P73005
    EphB4 Protein, Mouse (HEK293, His)

    Ephrin type-B receptor 4; EPHB4; HTK; MYK1; TYRO11

    		Mouse HEK293
    Ephb4 Protein, a receptor tyrosine kinase, plays a critical role in angiogenesis and development. Dysregulation of Ephb4 Protein has been associated with disorders like cancer and cardiovascular diseases. Targeting Ephb4 Protein may provide potential therapeutic interventions in these conditions by modulating angiogenesis, inhibiting tumor growth, and managing cardiovascular complications. EphB4 Protein, Mouse (HEK293, His) is the recombinant mouse-derived EphB4 protein, expressed by HEK293 , with C-His labeled tag. The total length of EphB4 Protein, Mouse (HEK293, His) is 524 a.a., with molecular weight of ~75 kDa.
  • HY-P75749
    EphB3 Protein, Mouse (537a.a, HEK293, His)

    Ephrin type-B receptor 3; mDK-5; Tyrosine-protein kinase receptor SEK-4; Sek4

    		Mouse HEK293
    The EphB3 protein is a receptor tyrosine kinase that binds to the transmembrane ephrin B ligand to initiate bidirectional signaling. The forward signal originates from the receptor, while the reverse signal originates from the ephrin ligand. EphB3 Protein, Mouse (537a.a, HEK293, His) is the recombinant mouse-derived EphB3 protein, expressed by HEK293 , with C-His labeled tag. The total length of EphB3 Protein, Mouse (537a.a, HEK293, His) is 537 a.a., with molecular weight of ~63 kDa.
  • HY-P70336
    EphA2 Protein, Human (HEK293, His)

    rHuEphrin type-A receptor 2/EphA2, His; Ephrin type-A receptor 2; Epithelial cell kinase; Tyrosine-protein kinase receptor ECK; EPHA2

    		Human HEK293
    EphA2 protein is a receptor tyrosine kinase that participates in bidirectional signaling with various ephrin A ligands, affecting cell migration, adhesion, proliferation and differentiation. It regulates cell adhesion and differentiation by interacting with DSG1 and inhibiting the ERK1/ERK2 signaling pathway. EphA2 Protein, Human (HEK293, His) is the recombinant human-derived EphA2 protein, expressed by HEK293 , with C-His labeled tag. The total length of EphA2 Protein, Human (HEK293, His) is 511 a.a., with molecular weight of 65-75 kDa.
  • HY-P72995
    EphA4 Protein, Mouse (HEK293, Fc)

    Ephrin type-A receptor 4; EPH-like kinase 8; EK8; EPHA4; HEK8; SEK; TYRO1

    		Mouse HEK293
    The EphA4 protein is a receptor tyrosine kinase that participates in contact-dependent bidirectional signaling with ephrin A and ephrin B ligands. EphA4 is activated by GPI-anchored EFNA and transmembrane EFNB and regulates cell morphology, integrin-dependent adhesion, and GTPase activity. EphA4 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived EphA4 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of EphA4 Protein, Mouse (HEK293, Fc) is 528 a.a., with molecular weight of ~110 kDa.
  • HY-P75236
    EphB2 Protein, Mouse (HEK293, Fc)

    EPHB2; Ephrin type-B receptor 2; EK5; DRT; EPHT3; ERK; HEK5; TYRO5

    		Mouse HEK293
    EphB2 protein is a member of the Eph receptor family and has a ligand-binding domain, a transmembrane region, and an intracellular kinase domain. It preferentially binds ephrin-B ligands and plays a role in nervous system and vascular development. EphB2 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived EphB2 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of EphB2 Protein, Mouse (HEK293, Fc) is 522 a.a., with molecular weight of ~96.6 kDa.
  • HY-P75238
    EphA4 Protein, Rat (HEK293, His)

    Ephrin type-A receptor 4; EPH-like kinase 8; EK8; EPHA4; HEK8; SEK; TYRO1

    		Rat HEK293
    EphA4 Protein, a receptor tyrosine kinase, engages in contact-dependent bidirectional signaling with ephrin-A and ephrin-B ligands. Activated by GPI-anchored EFNA and transmembrane EFNB, EphA4 regulates cell morphology, integrin-dependent adhesion, and GTPase activity. Crucial in nervous system development, it guides axonal projections, segregates motor and sensory axons, and influences synaptic plasticity. In injury repair and angiogenesis, EphA4 inhibits axonal regeneration and contributes to vascular formation. Its promiscuity extends to thymic epithelium development, cochlear organ of Corti formation, and phosphorylation of CAPRIN1 for membraneless compartment formation. EphA4 Protein, Rat (HEK293, His) is the recombinant rat-derived EphA4 protein, expressed by HEK293 , with C-His labeled tag. The total length of EphA4 Protein, Rat (HEK293, His) is 528 a.a., with molecular weight of ~70-80 kDa.
  • HY-P75240
    EphA2 Protein, Mouse (HEK293, His)

    Ephrin type-A receptor 2; Epithelial cell kinase; EPHA2; ECK

    		Mouse HEK293
    EphA2 protein is a receptor tyrosine kinase that promiscuously binds to ephrin A ligands to initiate bidirectional signaling. EphA2 is activated by ephrin-A1/EFNA1, regulates cell migration, adhesion, proliferation and differentiation, modulates DSG1 and inhibits ERK1/ERK2 signaling. EphA2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived EphA2 protein, expressed by HEK293 , with C-His labeled tag. The total length of EphA2 Protein, Mouse (HEK293, His) is 510 a.a., with molecular weight of ~65-95 kDa.
  • HY-P75241
    EphA1 Protein, Mouse (HEK293, His)

    Ephrin type-A receptor 1; hEpha1; EPHA1; EPH; EPHT; EPHT1

    		Mouse HEK293
    The EphA1 protein is a receptor tyrosine kinase that promiscuously binds to ephrin-A ligands on neighboring cells, initiating contact-dependent bidirectional signaling. The forward signal originates from the receptor and the reverse signal originates from the ephrin ligand. EphA1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived EphA1 protein, expressed by HEK293 , with C-His labeled tag. The total length of EphA1 Protein, Mouse (HEK293, His) is 522 a.a., with molecular weight of ~68 kDa.
  • HY-P75745
    EphA6 Protein, Mouse (HEK293, His)

    Ephrin type-A receptor 6; EPH homology kinase 2; EHK-2; Epha6

    		Mouse HEK293
    EphA6 Protein, a receptor tyrosine kinase, engages in promiscuous binding with GPI-anchored ephrin-A ligands, facilitating contact-dependent bidirectional signaling. EphA6 mediates intricate signaling exchanges between cells, playing a crucial role in diverse cellular processes through both forward and reverse signaling pathways. EphA6 Protein, Mouse (HEK293, His) is the recombinant mouse-derived EphA6 protein, expressed by HEK293 , with C-His labeled tag. The total length of EphA6 Protein, Mouse (HEK293, His) is 524 a.a., with molecular weight of ~65-70 kDa.
  • HY-P75746
    EphA7 Protein, Mouse (HEK293, His)

    Ephrin Type-A Receptor 7; mDK-1; EHK-3; EBK

    		Mouse HEK293
    The EphA7 protein is a receptor tyrosine kinase that participates in bidirectional signaling with GPI-anchored ephrin-A ligands (especially EFNA5). It affects brain development by regulating intercellular adhesion and repulsion, contributing to axonal guidance of corticothalamic and retinal axons. EphA7 Protein, Mouse (HEK293, His) is the recombinant mouse-derived EphA7 protein, expressed by HEK293 , with C-His labeled tag. The total length of EphA7 Protein, Mouse (HEK293, His) is 529 a.a., with molecular weight of 68-77 kDa.
  • HY-P75748
    EphB1 Protein, Mouse (HEK293, His)

    Ephrin type-B receptor 1; ELK; EK6; NET; EPHB1; EPHT2; HEK6

    		Mouse HEK293
    EphB1 protein is a receptor tyrosine kinase that participates in bidirectional signaling with ephrin B ligands (including EFNB1, EFNB2, and EFNB3). It plays a crucial role in retinal axon guidance, neural progenitor cell regulation, dendritic spine maturation, synapse formation, angiogenesis, targeted cell migration, and muscle stem cell maintenance. EphB1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived EphB1 protein, expressed by HEK293 , with C-His labeled tag. The total length of EphB1 Protein, Mouse (HEK293, His) is 522 a.a., with molecular weight of ~65-75 kDa.
  • HY-P70321
    EphA1 Protein, Human (522a.a, HEK293, His)

    rHuEphrin type-A receptor 1/EphA1, His; Ephrin type-A receptor 1; hEpha1; EPH tyrosine kinase; EPH tyrosine kinase 1; Erythropoietin-producing hepatoma receptor; Tyrosine-protein kinase receptor EPH; EPHA1; EPH; EPHT; EPHT1

    		Human HEK293
    The EphA1 protein is a receptor tyrosine kinase that promiscuously binds to ephrin-A ligands on neighboring cells, initiating contact-dependent bidirectional signaling. The forward signal originates from the receptor and the reverse signal originates from the ephrin ligand. EphA1 Protein, Human (522a.a, HEK293, His) is the recombinant human-derived EphA1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of EphA1 Protein, Human (522a.a, HEK293, His) is 522 a.a., with molecular weight of 70-85 kDa.
  • HY-P70381
    EphB1 Protein, Human (HEK293, Fc)

    rHuEphrin type-B receptor 1/EphB1, Fc; Ephrin Type-B Receptor 1; ELK; EPH Tyrosine Kinase 2; EPH-Like Kinase 6; EK6; hEK6; Neuronally-Expressed EPH; Related Tyrosine Kinase; NET; Tyrosine-Protein Kinase Receptor EPH-2; EPHB1; ELK; EPHT2; HEK6

    		Human HEK293
    The EphB1 protein is a receptor tyrosine kinase that promiscuously binds to the transmembrane ephrin-B ligand of adjacent cells, initiating bidirectional signaling. The forward signal originates from the receptor and the reverse signal originates from the ephrin ligand. EphB1 Protein, Human (HEK293, Fc) is the recombinant human-derived EphB1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of EphB1 Protein, Human (HEK293, Fc) is 523 a.a., with molecular weight of 85-100 kDa.
  • HY-P70382
    EphA4 Protein, Human (HEK293)

    rHuEphrin type-A receptor 4/EphA4; Ephrin type-A receptor 4; HEK8; SEK; TYRO1; EPHA4; Tyrosine-protein kinase receptor SEK; Tyrosine-protein kinase TYRO1; EK8; hEK8; EPH-like kinase 8

    		Human HEK293
    The EphA4 protein is a receptor tyrosine kinase that participates in bidirectional signaling with membrane-bound ephrin ligands including EFNA1 and EFNB3. EphA4 is activated by GPI-anchored ephrin A and transmembrane ephrin B and regulates cell morphology and integrin-dependent adhesion through regulation of Rac, Rap, and Rho GTPases. EphA4 Protein, Human (HEK293) is the recombinant human-derived EphA4 protein, expressed by HEK293 , with tag free. The total length of EphA4 Protein, Human (HEK293) is 528 a.a., with molecular weight of 60-80 kDa.
  • HY-P70842
    EphA7 Protein, Human (HEK293, His)

    Ephrin Type-A Receptor 7; EPH Homology Kinase 3; EHK-3; EPH-Like Kinase 11; EK11; hEK11; EPHA7; EHK3; HEK11

    		Human HEK293
    The EphA7 protein is a receptor tyrosine kinase that promiscuously binds to the GPI-anchored ephrin-A ligand to initiate bidirectional signaling. It participates in forward and reverse signaling pathways, uses EFNA5 as a functional ligand, regulates brain development and affects cell adhesion and repulsion. EphA7 Protein, Human (HEK293, His) is the recombinant human-derived EphA7 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of EphA7 Protein, Human (HEK293, His) is 529 a.a., with molecular weight of ~72.0 kDa.
  • HY-P75743
    EphA3 Protein, Rat (HEK293, His)

    Ephrin type-A receptor 3; EPH-like kinase 4; hEK4; EPHA3; ETK; ETK1; HEK; TYRO4

    		Rat HEK293
    The EphA3 protein is a receptor tyrosine kinase that promiscuously binds to membrane-bound ephrin ligands to initiate bidirectional signaling. Activation of EphA3 is known to preferentially bind to EFNA5 and regulates cell-cell adhesion, cytoskeletal organization, and migration. EphA3 Protein, Rat (HEK293, His) is the recombinant rat-derived EphA3 protein, expressed by HEK293 , with C-His labeled tag. The total length of EphA3 Protein, Rat (HEK293, His) is 521 a.a., with molecular weight of ~75-95 kDa.
  • HY-P75750
    EphB3 Protein, Rat (HEK293, His)

    Ephrin type-B receptor 3; mDK-5; Tyrosine-protein kinase receptor SEK-4; Sek4

    		Rat HEK293
    The EphB3 protein is a receptor tyrosine kinase that binds to the transmembrane ephrin B ligand to initiate bidirectional signaling. The forward signal originates from the receptor, while the reverse signal originates from the ephrin ligand. EphB3 Protein, Rat (HEK293, His) is the recombinant rat-derived EphB3 protein, expressed by HEK293 , with C-His labeled tag. The total length of EphB3 Protein, Rat (HEK293, His) is 508 a.a., with molecular weight of ~60-70 kDa.
Cat. No. Product Name Effect Purity