Fc alpha/mu Receptor
The Fc alpha/mu receptor (Fcα/μR, CD351) is a receptor that has dual specificity for IgA and IgM. Fcα/μR binds IgM with high affinity and IgA with a 10-fold lower affinity. Fcα/μR is expressed by both hematopoietic and non-hematopoietic cells, and has been shown to play an important role in humoral immune responses, especially in pro-inflammatory functions of marginal zone B cells in sepsis. Fcα/μR is a type I transmembrane protein that belongs to the immunoglobulin (Ig) superfamily and contains one Ig-like domain in the extracellular portion and a motif in the Ig-like domain conserved in the first Ig-like domain of the human, bovine and rodent poly-IgR. Mouse Fcα/μR contains a dileucine motif at residues 519 and 520 in the cytoplasmic portion that is involved in receptor internalization. However, since the human Fcα/μR does not have a di-leucine motif in its cytoplasmic domain, it remains unclear whether and how it transduces a signal in humans.
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Fc alpha/mu Receptor Recombinant Proteins (1)
Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
