1. Signaling Pathways
  2. Stem Cell/Wnt
  3. YAP

YAP

The transcriptional coactivator Yes-associated protein (YAP) is a major regulator of organ size and proliferation in vertebrates. As such, YAP can act as an oncogene in several tissue types if its activity is increased aberrantly. YAP enhances multiple processes known to be important for tumor progression and metastasis, including cellular proliferation, transformation, migration, and invasion.

YAP Related Products (5):

Cat. No. Product Name Effect Purity
  • HY-B0146
    Verteporfin Inhibitor 99.58%
    Verteporfin is a photosensitizer for photodynamic therapy to eliminate the abnormal blood vessels in the eye associated with conditions such as age-related macular degeneration. Verteporfin is a YAP inhibitor which disrupts YAP-TEAD interactions.
  • HY-111429
    YAP/TAZ inhibitor-1 Inhibitor 98.04%
    YAP/TAZ inhibitor-1 is a YAP/TAZ inhibitor extracted from patent WO2017058716A1, Compound 1, has an IC50 of <0.100 μΜ in firefly luciferase assay.
  • HY-P1728A
    Super-TDU (1-31) TFA
    Super-TDU (1-31) is a peptide of Super-TDU, which is an inhibitor of YAP-TEADs, shows potent anti-tumor activity.
  • HY-P1728
    Super-TDU 1-31
    Super-TDU (1-31) is a peptide of Super-TDU, which is an inhibitor of YAP-TEADs, shows potent anti-tumor activity.
  • HY-P1727A
    Super-TDU (TFA) Antagonist
    Super-TDU TFA is a specific YAP antagonist therapy against gastric cancer targeting YAP-TEADs interaction.
Isoform Specific Products

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Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.