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Articles (39)

  • Wnt/β-catenin and tumor EMT


    Epithelial-Mesenchymal Transition (EMT) is closely related to the plasticity of tumor cells and is a necessary process for tumor metastasis. Wnt/β-catenin is one of the main actors involved in the EMT process. Today, we’re here to popularize the tumor EMT and Wnt/β-catenin pathway~

  • Compound Screening Guide!


    How to use compound library? How to design an experiment if you buy a compound library? Want a specific experimental protocol? This article will introduce popular experimental techniques and provide new ideas for publishing high level literature.

  • What should we know about the "undruggable" target KRAS?


    KRAS, a gene we've heard so much about, has quickly risen to fame after shedding its "undruggable" label. After reading numerous articles, it's easy to feel overwhelmed and wonder: What exactly should we know about this often-discussed but previously "undruggable" target KRAS?

  • How to Cryopreserve and Thaw Cells More Effectively?


    Are frozen cells always damaged? Is the survival rate of revived cells low? When is it appropriate to freeze cells? What should be considered when reviving them? Today, we're sharing a guide to avoid pitfalls in cell freezing and revival!

  • FDA Annual Review | Record-breaking number of new drug approvals in 2023!


    FDA Annual Review | Record-breaking number of new drug approvals in 2023!

  • The Application of Tumor Organoids in Drug Screening


    A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening of diseases such as cancer, infectious diseases, and rare diseases.

  • Explanation of multiple immunohistochemistry techniques


    IHC is an indispensable technique for studying tissue morphology and in situ antigen expression, but usually only one or two antigens in tissues can be stained for analysis. It cannot judge the results more intuitively. Today, Little M will introduce you to the upgraded version mlHC.

  • FDA Approved Drug List!


    In the first half of 2023 (as of June 27), the FDA approved 26 new drugs, let's take you learn about it through the article.

  • WHO Inventory | Ten Most Potential Small Molecules


    WHO's Q2 drug list has been updated. Let's take you through the list of the most noteworthy small molecule drugs that we should pay attention to.

  • Organoid Culture: Questions & Answers


    In the last issue, we conducted a live lecture on the theme of organoid culture. Today, we have a special topic to solve your doubts in the last live class!