1. Recombinant Proteins
  2. Cytokines and Growth Factors

Cytokines and Growth Factors

Cytokines are a large group of low molecular weight proteins, polypeptides or glycoproteins that are secreted by various immune cells including macrophages, lymphocytes and mast cells, as well as other cell types such as endothelial cells. They play important roles in regulating cell growth, differentiation, and activation, and are involved in many aspects of both innate and adaptive immune responses. Cytokines include interleukins, chemokines, interferons and other signalling molecules[1][2][3].
Growth factors are soluble signaling molecules capable of stimulating a variety of cellular processes including cell proliferation, migration, differentiation and multicellular morphogenesis during development and tissue healing. Usually, Growth factors are secreted proteins or steroid hormones[4][5].
The term “Growth factor” and “Cytokine” are often used interchangeably. Some growth factors are small peptides called cytokines. The cytokines affecting cell growth/differentiation signaling pathways are considered growth factors, such as GM-CSF[5][6].

Cat. No. Product Name / Synonyms Species Source
  • HY-P7018
    IGF-I/IGF-1 Protein, Human (70a.a)

    rHuIGF-1; IGF-IA; Somatamedin C; MGF; IGF-I

    Human E. coli
    IGF-I/IGF-1 Protein, Human (70a.a) is a mitogenic cytokine, binds to IGF type 1 receptor, and modulates growth in many tissues, such as nervous tissue, lymphoid tissue, reproductive tissue, smooth muscle, endothelium, and bone; IGF-I/IGF-1 Protein also mediates neuroprotective mechanism.
  • HY-P7077
    IL-2 Protein, Mouse

    rMuIL-2; IL2; T-cell Growth Factor; TCGF; Aldesleukin

    Mouse E. coli
    IL-2 Protein, Mouse is an immunomodulatory cytokine with widely varying functions including promotion of apoptosis, proliferation and survival of lymphocytes.
  • HY-P7118
    TGF beta 1/TGFB1 Protein, Human (CHO)

    TGF-beta-1; TGFB1; TGFB; rHuTGF-β1

    Human CHO
    TGF beta 1/TGFB1 Protein is initially identified as a growth factor that induces the growth of rodent fibroblasts. TGF beta 1/TGFB1 Protein inhibits the cell cycle in the G1 phase. TGF beta 1/TGFB1 is an endogenous factor controlling apoptosis in normal and pathological tissues. TGF beta 1/TGFB1 Protein, Human is a recombinant protein (A279-S390) produced by CHO cells.
  • HY-P7037
    IL-2 Protein, Human

    rHuIL-2; IL2; T-cell Growth Factor; TCGF; Aldesleukin

    Human E. coli
    IL-2 Protein, Human is an adjunctive immunotherapeutic agent to treat tuberculosis (TB).
  • HY-P7080
    IL-4 Protein, Mouse (CHO)

    rMuIL-4; BSF-1; Binetrakin; Lymphocyte stimulatory factor 1; Pitrakinra

    Mouse CHO
    IL-4 Protein, Mouse (CHO) is a species-specific cytokine which promotes the proliferation, differentiation and cell-surface protein modulation of B lymphocytes.
  • HY-P7016
    GM-CSF Protein, Human (CHO)

    rHuGM-CSF; CSF-2; MGI-1GM; Pluripoietin-alpha; Molgramostin; Sargramostim

    Human CHO
    GM-CSF Protein, Human (CHO) is a hematopoietic growth factor and immune modulator.
  • HY-P7025A
    IFN-gamma Protein, Human (143a.a, CHO)

    rHuIFN-γ; IFNG; IFN-gamma; Interferon gamma

    Human CHO
    IFN-gamma Protein, Human (CHO) is a cytokine with potent immunomodulatory, antiviral and antitumor activities.
  • HY-P70543
    TGF beta 1/TGFB1 Protein, Human (112a.a, HEK293)

    Transforming Growth Factor Beta-1; TGF-Beta-1; Latency-Associated Peptide; LAP; TGFB1; TGFB; TGF-β1; TGF beta1; TGFbeta 1; TGF-beta 1; TGFbeta; TGF-beta-1

    Human HEK293
    TGF beta 1/TGFB1 Protein is initially identified as a growth factor that induces the growth of rodent fibroblasts. TGF beta 1/TGFB1 Protein inhibits the cell cycle in the G1 phase. TGF beta 1/TGFB1 is an endogenous factor controlling apoptosis in normal and pathological tissues. TGF beta 1/TGFB1 Protein, Human (112a.a, HEK293) is a recombinant protein (A279-S390) produced by HEK293 cells.
  • HY-P7085A
    M-CSF Protein, Mouse (CHO)

    rMuM-CSF; CSF-1; MGI-IM

    Mouse CHO
    M-CSF Protein, Mouse (CHO) is a pro-inflammatory cytokine, binds to its receptor CSF1R, and is involved in the development and proliferation of cells of the monocyte/macrophage lineage and participates in the induction of osteoclasts which are important in the destruction of bone and cartilage and in the periarticular osteoporotic changes.
  • HY-P70783
    LR3 IGF-I/IGF-1 Protein, Human (83a.a, E51R)

    Long R3 IGF-I; Insulin-like growth factor I; MGF; Somatomedin-C; IBP1

    Human E. coli
    The LR3 IGF-I/IGF-1 protein is similar to insulin and has potent growth-promoting activity that exceeds the efficacy of insulin. As a potential physiological regulator, it stimulates glucose transport and glycogen synthesis in osteoblasts even at significantly lower concentrations than insulin. LR3 IGF-I/IGF-1 Protein, Human (83a.a, E51R) is the recombinant human-derived LR3 IGF-I/IGF-1 protein, expressed by E. coli , with tag free. and E51R, , , , mutation. The total length of LR3 IGF-I/IGF-1 Protein, Human (83a.a, E51R) is 70 a.a., with molecular weight of ~11.0 kDa.
  • HY-P7074A
    IL-10 Protein, Mouse (CHO)

    rMuIL-10; CSIF

    Mouse CHO
    IL-10 Protein, Mouse (CHO) is a potent CHO cell derived anti-inflammatory cytokine results in increased immune-mediated demyelination in mice infected with a neurotropic coronavirus.
  • HY-P70750G
    GMP IL-4 Protein, Human (HEK293)

    Interleukin-4; IL-4; B-Cell Stimulatory Factor 1; BSF-1; Binetrakin; Lymphocyte Stimulatory Factor 1; Pitrakinra; IL4

    Human HEK293
    GMP IL-4 Protein, Human (HEK293) is a recombinant GMP-grade protein produced by HEK293 cells with C-His tag. IL-4 is an anti-inflammatory cytokine acting as a pleiotropic regulator of numerous immune and inflammatory processes.
  • HY-P70776G
    GMP IL-15 Protein, Human

    Interleukin-15; IL-15; IL15

    Human E. coli
    IL-15 protein regulates immune cells, stimulates the proliferation of NK cells, T cells, and B cells, and promotes cytokine secretion. GMP IL-15 Protein, Human is the recombinant human-derived IL-15 protein, expressed by E. coli , with tag free. The total length of GMP IL-15 Protein, Human is 114 a.a., with molecular weight of ~12.0 kDa.
  • HY-P70567G
    GMP GM-CSF Protein, Human (HEK293, His)

    Granulocyte-macrophage colony-stimulating factor; Colony-stimulating factor; CSF; Molgramostin and Sargramostim

    Human HEK293
    The GM-CSF protein functions as a key cytokine that promotes the growth and differentiation of hematopoietic precursor cells of different lineages, such as granulocytes, macrophages, eosinophils, and erythrocytes. In its monomeric form, GM-CSF acts as a signaling molecule, orchestrating complex receptor assemblies. GMP GM-CSF Protein, Human (HEK293, His) is the recombinant human-derived GM-CSF protein, expressed by HEK293 , with C-6*His labeled tag. The total length of GMP GM-CSF Protein, Human (HEK293, His) is 127 a.a., with molecular weight of 17-30 kDa.
  • HY-P70755G
    GMP IL-7 Protein, Human (HEK293, His)

    Interleukin-7; IL-7; IL7

    Human HEK293
    IL-7 protein is an important hematopoietic cytokine that is essential for the development, expansion and survival of T cells and B cells, regulating mature lymphocyte populations and maintaining lymphatic homeostasis. IL-7 interacts with IL7RA and CSF2RG subunits, activates kinases, including JAK1 or JAK3, and initiates signaling cascades, such as the PI3K/Akt/mTOR or JAK-STAT5 pathway. GMP IL-7 Protein, Human (HEK293, His) is the recombinant human-derived IL-7 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of GMP IL-7 Protein, Human (HEK293, His) is 152 a.a., with molecular weight of 19-30 kDa.
  • HY-P70787
    IGF-I/IGF-1 Protein, Human (67a.a)

    Insulin-Like Growth Factor I; IGF-I; Mechano Growth Factor; MGF; Somatomedin-C; IGF1; IBP1

    Human E. coli
    The LR3 IGF-I/IGF-1 protein is similar to insulin and has potent growth-promoting activity that exceeds the efficacy of insulin. As a potential physiological regulator, it stimulates glucose transport and glycogen synthesis in osteoblasts even at significantly lower concentrations than insulin. IGF-I/IGF-1 Protein, Human (67a.a) is the recombinant human-derived IGF-I/IGF-1 protein, expressed by E. coli , with tag free. The total length of IGF-I/IGF-1 Protein, Human (67a.a) is 67 a.a., with molecular weight of ~9.0 kDa.
  • HY-P7121
    HGF Protein, Human (CHO)

    rHuHGF; Hepatopoietin-A; SF

    Human CHO
    HGF Protein, Human (CHO) is a cytokine binding to Met tyrosine kinase receptor, and exhibits biological activities.
  • HY-P70758
    IL-2 Protein, Human (HEK293, His)

    Interleukin-2; IL-2; T-Cell Growth Factor; TCGF; Aldesleukin; IL2

    Human HEK293
    IL-2 protein is mainly produced by activated CD4-positive helper T cells and plays an important role in immune response and tolerance. Binding to IL-2R induces downstream signaling through JAK1 and JAK3 phosphorylation, thereby activating various pathways, including STAT, PI3K, and MAPK. IL-2 Protein, Human (HEK293, His) is the recombinant human-derived IL-2 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of IL-2 Protein, Human (HEK293, His) is 133 a.a., with molecular weight of 14-18 kDa.
  • HY-P7042
    IL-4 Protein, Human (CHO)

    rHuIL-4; BSF-1; Binetrakin; Lymphocyte stimulatory factor 1; Pitrakinra

    Human CHO
    IL-4 Protein, Human (CHO) is a CHO cell derived, potent lymphoid cell growth factor, which stimulates the growth and survivability of B-cells and T-cells.
  • HY-P7044
    IL-6 Protein, Human

    rHuIL-6; BSF-2; CDF; Hybridoma growth factor; IFN-beta-2

    Human E. coli
    IL-6 Protein, Human is a potent inducer of the synthesis of acute phase proteins in adult human hepatocytes.
Cat. No. Product Name Effect Purity