1. Recombinant Proteins
  2. Receptor Proteins
  3. Killer-Cell Immunoglobulin-like Receptors

Killer-Cell Immunoglobulin-like Receptors

Cat. No. Product Name / Synonyms Species Source
  • HY-P74793
    KIR2DL1 Protein, Human (245a.a, HEK293, His)

    Killer cell immunoglobulin-like receptor 2DL1; NKAT-1; CD158a; KIR2DL1

    Human HEK293
    KIR2DL1, found on NK cells, serves as a receptor for specific HLA-C alleles, inhibiting NK cell activity to prevent cell lysis. This regulatory function involves interactions with ARRB2 and, additionally, engages PTPN6 and PTPN11. The interaction's enhancement by ARRB2 underscores KIR2DL1's role in complex signaling networks that modulate NK cell function. KIR2DL1 Protein, Human (245a.a, HEK293, His) is the recombinant human-derived KIR2DL1 protein, expressed by HEK293 , with C-His labeled tag. The total length of KIR2DL1 Protein, Human (245a.a, HEK293, His) is 245 a.a., with molecular weight of ~45 kDa.
  • HY-P78474
    KIR2DL3 Protein, Human (HEK293, His-Avi)

    cl-6; KIR2DL3; KIRCL23; KIR-K7b; KIR-K7c; MGC129943; NKAT; NKAT2; NKAT-2; NKAT2A; NK-receptor; p58; NKAT2GL183; CD158b; CD158B2; GL183; KIR-023GB; KIR2DS5; NKAT2B

    Human HEK293
    KIR2DL3, found on NK cells, selectively recognizes HLA-C alleles like HLA-Cw1, HLA-Cw3, and HLA-Cw7. Its interaction leads to inhibitory effects, preventing NK cell activity and cell lysis. KIR2DL3's association with ARRB2 underscores its role in cellular signaling pathways, intricately modulating NK cell functions. KIR2DL3 Protein, Human (HEK293, His-Avi) is the recombinant human-derived KIR2DL3 protein, expressed by HEK293, with C-Avi, C-His labeled tag. The total length of KIR2DL3 Protein, Human (HEK293, His-Avi) is 224 a.a., with molecular weight of 45-52 kDa.
  • HY-P71823
    KIR2DS1 Protein, Human (P.pastoris, His)

    KIR2DS1; CD158 antigen-like family member H; MHC class I NK cell receptor Eb6 ActI

    Human P. pastoris
    KIR2DS1, on NK cells, acts as a receptor for specific HLA-C alleles, like w6, without inhibiting NK cell activity. Interacting with the adapter protein TYROBP/DAP12, their collaboration enhances KIR2DS1 stability at the cell surface. This dynamic interplay highlights the intricate regulatory mechanisms associated with KIR2DS1, contributing to the modulation of NK cell responses. KIR2DS1 Protein, Human (P.pastoris, His) is the recombinant human-derived KIR2DS1 protein, expressed by P. pastoris , with N-6*His labeled tag. The total length of KIR2DS1 Protein, Human (P.pastoris, His) is 224 a.a., with molecular weight of ~34 kDa.
  • HY-P77041
    KIR2DL5/CD158f Protein, Human (HEK293, Fc)

    Killer cell immunoglobulin-like receptor 2DL5A; CD158f1; KIR2DL5A; CD158F

    Human HEK293
    KIR2DL5/CD158f, present on NK cells, acts as a receptor for HLA-C alleles. Its inhibitory function finely tunes NK cell activity, preventing cell lysis by interacting with specific HLA-C molecules. This dynamic engagement contributes to the nuanced balance of inhibitory signals in the immune system, regulating NK cell responses to potential targets. KIR2DL5/CD158f Protein, Human (HEK293, Fc) is the recombinant human-derived KIR2DL5/CD158f protein, expressed by HEK293 , with C-hFc labeled tag. The total length of KIR2DL5/CD158f Protein, Human (HEK293, Fc) is 219 a.a., with molecular weight of ~50.3 KDa.
  • HY-P77729
    KIR2DL5/CD158f Protein, Human (HEK293, His-Avi)

    KIR2DL5A; CD158F; CD158F1; KIR2DL5; KIR2DL5.1; KIR2DL5.3; KIR2DL5A; KIR2DL5B

    Human HEK293
    KIR2DL5/CD158f, present on NK cells, acts as a receptor for HLA-C alleles. Its inhibitory function finely tunes NK cell activity, preventing cell lysis by interacting with specific HLA-C molecules. This dynamic engagement contributes to the nuanced balance of inhibitory signals in the immune system, regulating NK cell responses to potential targets. KIR2DL5/CD158f Protein, Human (HEK293, His-Avi) is the recombinant human-derived KIR2DL5/CD158f protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of KIR2DL5/CD158f Protein, Human (HEK293, His-Avi) is 219 a.a., with molecular weight of 45-52 kDa.
  • HY-P7794
    CD158d/KIR2DL4 Protein, Human (HEK293, His)

    rHuCD158d, His; Killer Cell Immunoglobulin-Like Receptor 2DL4; CD158 Antigen-Like Family Member D; KIR-103AS; MHC Class I NK Cell Receptor KIR103AS; CD158d; KIR2DL4; KIR103AS

    Human HEK293
    CD158d/KIR2DL4 Protein, Human (HEK293, His) is a recombinant human CD158d expressed in HEK 293 cells with a His tag at the N-terminus. CD158d/KIR2DL4 Protein is an NK cell-activating receptor with inhibitory potential.
  • HY-P77970
    KIR2DL2/CD158b1 Protein, Human (HEK293, His-Avi)

    Killer cell immunoglobulin-like receptor 2DL2; CD158 antigen-like family member B1; MHC class I NK cell receptor; NKAT-6; p58 NK receptor CL-43; CD158b1; KIR2DL2; CD158B1; NKAT6

    Human HEK293
    KIR2DL2/CD158b1, found on NK cells, functions as a receptor for HLA-Cw1, Cw3, Cw7, and Cw8 allotypes. Its key role is to inhibit NK cell activity, serving as a regulator to prevent cellular lysis. Interacting with specific HLA-C molecules, KIR2DL2/CD158b1 contributes to the delicate balance of inhibitory signals in the immune system, shaping the responsiveness of NK cells to potential targets. KIR2DL2/CD158b1 Protein, Human (HEK293, His-Avi) is the recombinant human-derived KIR2DL2/CD158b1 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of KIR2DL2/CD158b1 Protein, Human (HEK293, His-Avi) is 224 a.a., with molecular weight of 45-50 kDa.
  • HY-P78475
    KIR3DL3/CD158z Protein, Human (HEK293, His-Avi)

    CD158Z; KIR2DS2; KIR3DL7; KIR44; KIRC1; KIR3DL3

    Human HEK293
    KIR3DL3/CD158z, on natural killer cells, potentially inhibits NK cell activity, contributing to the prevention of cell lysis. This regulatory role underscores the significance of KIR3DL3 in modulating NK cell functions and maintaining immune homeostasis. KIR3DL3/CD158z Protein, Human (HEK293, His-Avi) is the recombinant human-derived KIR3DL3/CD158z protein, expressed by HEK293, with C-Avi, C-His labeled tag. The total length of KIR3DL3/CD158z Protein, Human (HEK293, His-Avi) is 297 a.a., with molecular weight of 48-52 kDa.
  • HY-P70354
    KIR2DL3 Protein, Human (HEK293, His)

    rHuKiller cell immunoglobulin-like receptor 2DL3/KIR2DL3, His; Killer Cell Immunoglobulin-Like Receptor 2DL3; CD158 Antigen-Like Family Member B2; KIR-023GB; Killer Inhibitory Receptor cl 2-3; MHC Class I NK Cell Receptor; NKAT2a; NKAT2b; Natural Killer-Associated Transcript 2; NKAT-2; p58 Natural Killer Cell Receptor Clone C

    Human HEK293
    KIR2DL3, found on NK cells, selectively recognizes HLA-C alleles like HLA-Cw1, HLA-Cw3, and HLA-Cw7. Its interaction leads to inhibitory effects, preventing NK cell activity and cell lysis. KIR2DL3's association with ARRB2 underscores its role in cellular signaling pathways, intricately modulating NK cell functions. KIR2DL3 Protein, Human (HEK293, His) is the recombinant human-derived KIR2DL3 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of KIR2DL3 Protein, Human (HEK293, His) is 224 a.a., with molecular weight of 35-50 kDa.
  • HY-P74792
    KIR2DL1 Protein, Human (HEK293, Fc)

    Killer cell immunoglobulin-like receptor 2DL1; NKAT-1; CD158a; KIR2DL1

    Human HEK293
    KIR2DL1, found on NK cells, serves as a receptor for specific HLA-C alleles, inhibiting NK cell activity to prevent cell lysis. This regulatory function involves interactions with ARRB2 and, additionally, engages PTPN6 and PTPN11. The interaction's enhancement by ARRB2 underscores KIR2DL1's role in complex signaling networks that modulate NK cell function. KIR2DL1 Protein, Human (HEK293, Fc) is the recombinant human-derived KIR2DL1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of KIR2DL1 Protein, Human (HEK293, Fc) is 245 a.a., with molecular weight of ~70 kDa.
  • HY-P75901
    KIR2DL3 Protein, Human (HEK293, Fc)

    Killer cell immunoglobulin-like receptor 2DL3; NKAT2a; NKAT-2; CD158b2; KIRCL23

    Human HEK293
    KIR2DL3, found on NK cells, selectively recognizes HLA-C alleles like HLA-Cw1, HLA-Cw3, and HLA-Cw7. Its interaction leads to inhibitory effects, preventing NK cell activity and cell lysis. KIR2DL3's association with ARRB2 underscores its role in cellular signaling pathways, intricately modulating NK cell functions. KIR2DL3 Protein, Human (HEK293, Fc) is the recombinant human-derived KIR2DL3 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of KIR2DL3 Protein, Human (HEK293, Fc) is 245 a.a., with molecular weight of ~51.6 kDa.
  • HY-P78165
    KIR2DL1 Protein, Human (Biotinylated, HEK293, His-Avi)

    CD158Ankat1; CD158A; cl-42; KIR2DL1; NKAT; NKAT-1; p58.1; KIR-K64; KIR221; KIR2DL1/KIR2DS5

    Human HEK293
    KIR2DL1, found on NK cells, serves as a receptor for specific HLA-C alleles, inhibiting NK cell activity to prevent cell lysis. This regulatory function involves interactions with ARRB2 and, additionally, engages PTPN6 and PTPN11. The interaction's enhancement by ARRB2 underscores KIR2DL1's role in complex signaling networks that modulate NK cell function. KIR2DL1 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived KIR2DL1 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of KIR2DL1 Protein, Human (Biotinylated, HEK293, His-Avi) is 221 a.a., with molecular weight of 48-60 kDa.
  • HY-P78166
    KIR2DL3 Protein, Human (Biotinylated, HEK293, His-Avi)

    cl-6; KIR2DL3; KIRCL23; KIR-K7b; KIR-K7c; MGC129943; NKAT; NKAT2; NKAT-2; NKAT2A; NK-receptor; p58; NKAT2GL183; CD158b; CD158B2; GL183; KIR-023GB; KIR2DS5; NKAT2B

    Human HEK293
    KIR2DL3, found on NK cells, selectively recognizes HLA-C alleles like HLA-Cw1, HLA-Cw3, and HLA-Cw7. Its interaction leads to inhibitory effects, preventing NK cell activity and cell lysis. KIR2DL3's association with ARRB2 underscores its role in cellular signaling pathways, intricately modulating NK cell functions. KIR2DL3 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived KIR2DL3 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of KIR2DL3 Protein, Human (Biotinylated, HEK293, His-Avi) is 224 a.a., with molecular weight of 45-52 kDa.
  • HY-P78473
    KIR2DL1 Protein, Human (HEK293, His-Avi)

    CD158Ankat1; CD158A; cl-42; KIR2DL1; NKAT; NKAT-1; p58.1; KIR-K64; KIR221; KIR2DL1/KIR2DS5

    Human HEK293
    KIR2DL1, found on NK cells, serves as a receptor for specific HLA-C alleles, inhibiting NK cell activity to prevent cell lysis. This regulatory function involves interactions with ARRB2 and, additionally, engages PTPN6 and PTPN11. The interaction's enhancement by ARRB2 underscores KIR2DL1's role in complex signaling networks that modulate NK cell function. KIR2DL1 Protein, Human (HEK293, His-Avi) is the recombinant human-derived KIR2DL1 protein, expressed by HEK293, with C-Avi, C-His labeled tag. The total length of KIR2DL1 Protein, Human (HEK293, His-Avi) is 221 a.a., with molecular weight of 40-52 kDa.
  • HY-P71815
    KIR2DS3 Protein, Human (P.pastoris, His)

    KIR2DS3; NKAT7Killer cell immunoglobulin-like receptor 2DS3; MHC class I NK cell receptor; Natural killer-associated transcript 7; NKAT-7

    Human P. pastoris
    KIR2DS3, present on NK cells, selectively recognizes HLA-C alleles. In contrast to inhibitory KIRs, KIR2DS3 lacks inhibitory effects on NK cell activity. Its role is likely in activating or modulating NK cell functions, contributing to the nuanced balance of signals regulating the immune response. KIR2DS3 Protein, Human (P.pastoris, His) is the recombinant human-derived KIR2DS3 protein, expressed by P. pastoris , with N-His labeled tag. The total length of KIR2DS3 Protein, Human (P.pastoris, His) is 224 a.a., with molecular weight of ~26.7 kDa.
  • HY-P77042
    KIR3DL3/CD158z Protein, Human (HEK293, His)

    Killer cell immunoglobulin-like receptor 3DL3; CD158Z; KIR3DL7; KIRC1

    Human HEK293
    KIR3DL3/CD158z, on natural killer cells, potentially inhibits NK cell activity, contributing to the prevention of cell lysis. This regulatory role underscores the significance of KIR3DL3 in modulating NK cell functions and maintaining immune homeostasis. KIR3DL3/CD158z Protein, Human (HEK293, His) is the recombinant human-derived KIR3DL3/CD158z protein, expressed by HEK293 , with C-His labeled tag. The total length of KIR3DL3/CD158z Protein, Human (HEK293, His) is 297 a.a., with molecular weight of ~33.7 KDa.
  • HY-P77730
    KIR2DL5/CD158f Protein, Human (Biotinylated, HEK293, His-Avi)

    KIR2DL5A; CD158F; CD158F1; KIR2DL5; KIR2DL5.1; KIR2DL5.3; KIR2DL5A; KIR2DL5B

    Human HEK293
    KIR2DL5/CD158f, present on NK cells, acts as a receptor for HLA-C alleles. Its inhibitory function finely tunes NK cell activity, preventing cell lysis by interacting with specific HLA-C molecules. This dynamic engagement contributes to the nuanced balance of inhibitory signals in the immune system, regulating NK cell responses to potential targets. KIR2DL5/CD158f Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived KIR2DL5/CD158f protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of KIR2DL5/CD158f Protein, Human (Biotinylated, HEK293, His-Avi) is 219 a.a., with molecular weight of 45-52 kDa.
  • HY-P77971
    KIR2DL2/CD158b1 Protein, Human (Biotinylated, HEK293, His-Avi)

    Killer cell immunoglobulin-like receptor 2DL2; CD158 antigen-like family member B1; MHC class I NK cell receptor; NKAT-6; p58 NK receptor CL-43; CD158b1; KIR2DL2; CD158B1; NKAT6

    Human HEK293
    KIR2DL2/CD158b1, found on NK cells, functions as a receptor for HLA-Cw1, Cw3, Cw7, and Cw8 allotypes. Its key role is to inhibit NK cell activity, serving as a regulator to prevent cellular lysis. Interacting with specific HLA-C molecules, KIR2DL2/CD158b1 contributes to the delicate balance of inhibitory signals in the immune system, shaping the responsiveness of NK cells to potential targets. KIR2DL2/CD158b1 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived KIR2DL2/CD158b1 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of KIR2DL2/CD158b1 Protein, Human (Biotinylated, HEK293, His-Avi) is 224 a.a., with molecular weight of 45-60 kDa.
  • HY-P78167
    KIR3DL3/CD158z Protein, Human (Biotinylated, HEK293, His-Avi)

    CD158Z; KIR2DS2; KIR3DL7; KIR44; KIRC1; KIR3DL3

    Human HEK293
    KIR3DL3/CD158z, on natural killer cells, potentially inhibits NK cell activity, contributing to the prevention of cell lysis. This regulatory role underscores the significance of KIR3DL3 in modulating NK cell functions and maintaining immune homeostasis. KIR3DL3/CD158z Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived KIR3DL3/CD158z protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of KIR3DL3/CD158z Protein, Human (Biotinylated, HEK293, His-Avi) is 297 a.a., with molecular weight of 48-50 kDa.
Cat. No. Product Name Effect Purity